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ONTOLOGY REPORT - ANNOTATIONS

Term:CD86 biosynthetic process
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Accession:GO:0035781 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.
Synonyms:exact_synonym: CD86 anabolism;   CD86 biosynthesis;   CD86 formation;   CD86 synthesis

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CD86 biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem106a transmembrane protein 106A involved_in ISS
ISO		 GO_REF:0000024
(MGI:6216178|PMID:26215746)		 UniProt
RGD		 PMID:26215746 GO_REF:0000024 MGI:6216178 NCBI chr10:89,484,269...89,493,288
Ensembl chr10:89,484,468...89,493,283 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:5554502|PMID:24218451) RGD PMID:24218451 MGI:5554502 NCBI chr 8:117,796,127...117,797,427
Ensembl chr 8:117,796,128...117,797,427 		JBrowse link
positive regulation of CD86 production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:6414704|PMID:26936882)		 Ensembl
RGD		 PMID:26936882 GO_REF:0000107 MGI:6414704 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11882
      primary metabolic process 10639
        protein metabolic process 5987
          glycoprotein metabolic process 362
            glycoprotein biosynthetic process 295
              CD86 biosynthetic process 3
                negative regulation of CD86 production 0
                positive regulation of CD86 production 1
                regulation of CD86 production + 1
Path 2
Term Annotations click to browse term
  biological_process 19612
    metabolic process 11882
      organic substance metabolic process 11417
        macromolecule metabolic process 9873
          cellular macromolecule metabolic process 8318
            cellular macromolecule biosynthetic process 5053
              glycoprotein biosynthetic process 295
                CD86 biosynthetic process 3
                  negative regulation of CD86 production 0
                  positive regulation of CD86 production 1
                  regulation of CD86 production + 1
paths to the root