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ONTOLOGY REPORT - ANNOTATIONS


Term:CD80 biosynthetic process
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Accession:GO:0035780 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.
Synonyms:exact_synonym: CD80 anabolism;   CD80 biosynthesis;   CD80 formation;   CD80 synthesis


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CD80 biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem106a transmembrane protein 106A ISS
ISO
GO_REF:0000024
(MGI:MGI:6216178|PMID:26215746)
UniProt
RGD
PMID:26215746 GO_REF:0000024, MGI:MGI:6216178 NCBI chr10:89,484,269...89,493,288
Ensembl chr10:89,484,468...89,493,283
JBrowse link
positive regulation of CD80 production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il33 interleukin 33 ISO
IEA
(MGI:MGI:6414704|PMID:26936882)
GO_REF:0000107
RGD
Ensembl
PMID:26936882 GO_REF:0000107, MGI:MGI:6414704 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      primary metabolic process 10901
        protein metabolic process 6214
          glycoprotein metabolic process 362
            glycoprotein biosynthetic process 296
              CD80 biosynthetic process 2
                negative regulation of CD80 production 0
                positive regulation of CD80 production 1
                regulation of CD80 production + 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          cellular macromolecule metabolic process 8535
            cellular macromolecule biosynthetic process 5074
              glycoprotein biosynthetic process 296
                CD80 biosynthetic process 2
                  negative regulation of CD80 production 0
                  positive regulation of CD80 production 1
                  regulation of CD80 production + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.