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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.



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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870
JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (MGI:7345668|PMID:36161949) MGI PMID:36161949 MGI:7345668 NCBI chr 6:18,450,019...18,458,456
Ensembl chr 6:18,412,219...18,459,438
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:31001245) UniProt PMID:31001245 NCBI chr  X:25,664,361...25,679,044 JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,658,408...47,683,519
Ensembl chr13:47,658,330...47,682,866
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,090,669...7,119,913 JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in ISO (PMID:32276428) UniProt PMID:32276428 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:19,027,014...19,031,467
Ensembl chr25:19,027,342...19,030,887
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA
IBA
(PMID:21873635) UniProt
Ensembl
UniProt
GO_Central
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr22:30,568,572...30,575,890
Ensembl chr22:30,568,572...30,575,890
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr30:32,246,394...32,264,251
Ensembl chr30:32,246,411...32,264,240
JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (MGI:6854654|PMID:33966596) MGI PMID:33966596 MGI:6854654 NCBI chr 7:30,873,556...30,884,257
Ensembl chr 7:30,873,556...30,883,370
JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:2,815,428...2,886,474
Ensembl chr15:2,859,979...2,894,425
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4879078|PMID:20920792) Ensembl
MGI
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 7:43,410,554...43,411,929
Ensembl chr 7:43,410,998...43,412,323
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within ISO (MGI:6101836|PMID:28728022) MGI PMID:28728022 MGI:6101836 NCBI chr14:27,140,692...27,166,652
Ensembl chr14:27,140,687...27,161,333
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 9:42,607,688...42,614,776
Ensembl chr 9:42,607,733...42,611,445
JBrowse link
G TMEM9 transmembrane protein 9 involved_in ISO (PMID:30374053) UniProt PMID:30374053 NCBI chr 7:2,069,017...2,087,961 JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMACR alpha-methylacyl-CoA racemase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,815,438...73,836,016
Ensembl chr 4:73,815,291...73,867,437
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISS
IEA
UniProt
Ensembl
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:18,252,543...18,266,033
Ensembl chr 6:18,254,139...18,266,033
JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:32,361,825...32,713,631
Ensembl chr 3:32,361,517...32,713,572
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,838,684...73,868,222
Ensembl chr 4:73,815,291...73,867,437
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:91,554,001...91,576,845
Ensembl chr 3:91,553,778...91,670,930
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17440
    biological regulation 12357
      regulation of biological quality 3123
        regulation of lysosomal lumen pH 21
          lysosomal lumen acidification 12
          lysosomal lumen pH elevation 5
Path 2
Term Annotations click to browse term
  biological_process 17440
    cellular process 16435
      cellular component organization or biogenesis 6522
        cellular component organization 6322
          organelle organization 3558
            vacuole organization 209
              lytic vacuole organization 85
                lysosome organization 85
                  regulation of lysosomal lumen pH 21
                    lysosomal lumen acidification 12
                    lysosomal lumen pH elevation 5
paths to the root