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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.



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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid acts_upstream_of_or_within ISO (MGI:7345668|PMID:36161949) MGI PMID:36161949 MGI:7345668
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:23,159,321...23,178,192
Ensembl chr  X:30,716,617...30,717,522
JBrowse link
G TMEM165 transmembrane protein 165 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,484,896...68,541,808
Ensembl chr 4:75,075,427...75,104,629
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:119,831,693...119,868,132
Ensembl chr12:123,201,663...123,236,019
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,026,525...33,052,252
Ensembl chr  X:40,730,677...40,756,209
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr2B:28,624,800...28,629,543 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:11722572) UniProt PMID:11722572
G CLN5 CLN5 intracellular trafficking protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:58,207,542...58,220,697
Ensembl chr13:77,253,203...77,263,759
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,156,583...47,215,805
Ensembl chr15:65,425,472...65,985,242
JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 acts_upstream_of_or_within ISO (MGI:6854654|PMID:33966596) MGI PMID:33966596 MGI:6854654 NCBI chr 1:142,974,260...142,987,071
Ensembl chr 1:146,758,325...146,770,978
JBrowse link
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609
JBrowse link
G SNAPIN SNAP associated protein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4879078|PMID:20920792) MGI
Ensembl
PMID:20920792 GO_REF:0000107 MGI:4879078 NCBI chr 1:129,014,668...129,018,428
Ensembl chr 1:132,644,320...132,647,095
JBrowse link
G TMEM106B transmembrane protein 106B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6101836|PMID:28728022) MGI
Ensembl
PMID:28728022 GO_REF:0000107 MGI:6101836 NCBI chr 7:12,905,192...12,931,170
Ensembl chr 7:12,250,010...12,270,693
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,412,229...28,416,840
Ensembl chr17:28,914,604...28,919,194
JBrowse link
G TMEM9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:176,734,640...176,771,476
Ensembl chr 1:181,037,050...181,056,841
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) UniProt PMID:10924275
G OCA2 OCA2 melanosomal transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,811,728...2,192,018
Ensembl chr15:25,181,386...25,523,774
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,357,549...76,398,571
Ensembl chr 5:81,743,254...81,784,565
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,049,647...1,074,903
Ensembl chr 4:967,494...993,030
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15351
    biological regulation 10732
      regulation of biological quality 2777
        regulation of lysosomal lumen pH 20
          lysosomal lumen acidification 12
          lysosomal lumen pH elevation 4
Path 2
Term Annotations click to browse term
  biological_process 15351
    cellular process 14224
      cellular homeostasis 810
        cellular chemical homeostasis 721
          cellular ion homeostasis 491
            cellular cation homeostasis 471
              cellular monovalent inorganic cation homeostasis 96
                regulation of cellular pH 70
                  regulation of intracellular pH 63
                    regulation of lysosomal lumen pH 20
                      lysosomal lumen acidification 12
                      lysosomal lumen pH elevation 4
paths to the root