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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lysosomal lumen pH
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Accession:GO:0035751 term browser browse the term
Definition:Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.



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regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC681325 hypothetical protein LOC681325 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:74,312,698...74,316,311
Ensembl chr  X:74,312,661...74,316,635
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:22012985) RGD PMID:22012985 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Spns1 sphingolipid transporter 1 acts_upstream_of_or_within ISO (MGI:7345668|PMID:36161949) RGD PMID:36161949 MGI:7345668 NCBI chr 1:180,942,088...180,949,415
Ensembl chr 1:180,942,088...180,949,370
JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IBA
ISO
PMID:21873635
(PMID:31001245)
RGD PMID:31001245 PMID:21873635 RGD:13792537 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269
JBrowse link
G Tmem165 transmembrane protein 165 involved_in ISO
ISS
(PMID:23569283)
GO_REF:0000024
RGD
UniProt
PMID:23569283 GO_REF:0000024 NCBI chr14:31,993,489...32,018,717
Ensembl chr14:31,993,493...32,018,717
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(MGI:5693670|PMID:26317472)
UniProt
RGD
PMID:26317472 GO_REF:0000024 MGI:5693670 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes involved_in ISO
ISS
IEA
(PMID:28013294)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:28013294 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,024,596...33,051,399
Ensembl chr12:33,024,650...33,051,393
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO
ISS
(PMID:32276428)
GO_REF:0000024
RGD
UniProt
PMID:32276428 GO_REF:0000024 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Ccdc115 coiled-coil domain containing 115 involved_in ISO (PMID:28296633) RGD PMID:28296633 NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO
IBA
(PMID:11722572)
PMID:21873635
RGD PMID:11722572 PMID:21873635 RGD:13792537 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cln5 CLN5, intracellular trafficking protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
JBrowse link
G Cln6 CLN6, transmembrane ER protein involved_in ISO (PMID:11722572) RGD PMID:11722572 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 acts_upstream_of_or_within ISO (MGI:6854654|PMID:33966596) RGD PMID:33966596 MGI:6854654 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Grn granulin precursor involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28073925)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:28073925 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO
ISS
(PMID:11722572)
PMID:8895569
RGD PMID:11722572 PMID:8895569 RGD:8553248 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Snapin SNAP-associated protein acts_upstream_of_or_within ISO MGI:3608768 (MGI:4879078|PMID:20920792) RGD PMID:20920792 MGI:4879078 NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231
JBrowse link
G Tmem106b transmembrane protein 106B acts_upstream_of_or_within ISO MGI:5319917 (MGI:6101836|PMID:28728022) RGD PMID:28728022 MGI:6101836 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Tmem199 transmembrane protein 199 involved_in ISO
ISS
(PMID:28296633)
GO_REF:0000024
RGD
UniProt
PMID:28296633 GO_REF:0000024 NCBI chr10:63,402,493...63,407,065
Ensembl chr10:63,402,494...63,407,108
JBrowse link
G Tmem9 transmembrane protein 9 involved_in ISO (PMID:30374053) RGD PMID:30374053 NCBI chr13:47,458,486...47,475,832
Ensembl chr13:47,458,498...47,475,832
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (PMID:10924275) RGD PMID:10924275 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein involved_in ISO (PMID:25513726), (PMID:32966160) RGD PMID:25513726 PMID:32966160 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074
JBrowse link
G Slc45a2 solute carrier family 45, member 2 involved_in ISO (PMID:32966160)
(MGI:7338895|PMID:35469906)
RGD PMID:32966160 PMID:35469906 MGI:7338895 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317
JBrowse link
G Tmem175 transmembrane protein 175 involved_in ISS
ISO
GO_REF:0000024
(PMID:35333573), (PMID:35750034)
UniProt
RGD
PMID:35333573 PMID:35750034 GO_REF:0000024 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19874
    biological regulation 13526
      regulation of biological quality 3234
        regulation of lysosomal lumen pH 21
          lysosomal lumen acidification 12
          lysosomal lumen pH elevation 4
Path 2
Term Annotations click to browse term
  biological_process 19874
    cellular process 18551
      cellular component organization or biogenesis 6759
        cellular component organization 6512
          organelle organization 3649
            vacuole organization 203
              lytic vacuole organization 85
                lysosome organization 85
                  regulation of lysosomal lumen pH 21
                    lysosomal lumen acidification 12
                    lysosomal lumen pH elevation 4
paths to the root