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ONTOLOGY REPORT - ANNOTATIONS

Term:mitophagy by internal vacuole formation
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Accession:GO:0035695 term browser browse the term
Definition:The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
Comment:In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
Synonyms:narrow_synonym: MIV-mediated mitophagy


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mitophagy by internal vacuole formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPATA18 spermatogenesis associated 18 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:39,163,001...39,206,217
Ensembl chr 8:39,163,088...39,203,956 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17876
    cellular process 17418
      process utilizing autophagic mechanism 520
        autophagy 520
          autophagy of mitochondrion 112
            mitophagy by internal vacuole formation 1
Path 2
Term Annotations click to browse term
  biological_process 17876
    cellular process 17418
      metabolic process 10672
        catabolic process 2609
          autophagy 520
            autophagy of mitochondrion 112
              mitophagy by internal vacuole formation 1
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