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ONTOLOGY REPORT - ANNOTATIONS


Term:mitophagy by internal vacuole formation
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Accession:GO:0035695 term browser browse the term
Definition:The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
Comment:In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
Synonyms:narrow_synonym: MIV-mediated mitophagy


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mitophagy by internal vacuole formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spata18 spermatogenesis associated 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:17,578,125...17,642,356 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17640
    cellular process 17222
      process utilizing autophagic mechanism 517
        autophagy 517
          autophagy of mitochondrion 108
            mitophagy by internal vacuole formation 1
Path 2
Term Annotations click to browse term
  biological_process 17640
    cellular process 17222
      metabolic process 11022
        catabolic process 2395
          autophagy 517
            autophagy of mitochondrion 108
              mitophagy by internal vacuole formation 1
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