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ONTOLOGY REPORT - ANNOTATIONS

Term:mitophagy by internal vacuole formation
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Accession:GO:0035695 term browser browse the term
Definition:The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
Comment:In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
Synonyms:narrow_synonym: MIV-mediated mitophagy


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mitophagy by internal vacuole formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPATA18 spermatogenesis associated 18 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:44,996,770...45,034,327
Ensembl chr13:44,996,517...45,033,626 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      process utilizing autophagic mechanism 534
        autophagy 534
          autophagy of mitochondrion 114
            mitophagy by internal vacuole formation 1
Path 2
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      metabolic process 15381
        catabolic process 2726
          autophagy 534
            autophagy of mitochondrion 114
              mitophagy by internal vacuole formation 1
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