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ONTOLOGY REPORT - ANNOTATIONS

Term:mitophagy by internal vacuole formation
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Accession:GO:0035695 term browser browse the term
Definition:The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
Comment:In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.
Synonyms:narrow_synonym: MIV-mediated mitophagy


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mitophagy by internal vacuole formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spata18 spermatogenesis associated 18 involved_in ISO
IEA
ISS
IBA		 (PMID:21264228)
GO_REF:0000107
GO_REF:0000024
GO_REF:0000033		 RGD
Ensembl
UniProt
GO_Central		 PMID:21264228 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      process utilizing autophagic mechanism 560
        autophagy 560
          autophagy of mitochondrion 113
            mitophagy by internal vacuole formation 1
Path 2
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        catabolic process 2871
          autophagy 560
            autophagy of mitochondrion 113
              mitophagy by internal vacuole formation 1
paths to the root