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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity
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Accession:GO:0035597 term browser browse the term
Definition:Catalysis of the reaction: N(6)-dimethylallyladenosine(37) in tRNA + [sulfur carrier]-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + [sulfur carrier]-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H+.
Synonyms:exact_synonym: N6-isopentenyladenosine methylthiotransferase activity;   i6A methylthiotransferase activity;   tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase activity
 xref: EC:2.8.4.3;   RHEA:37067


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tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 enables ISO
IBA 		MGI:5750452 (PMID:25738458)
(PMID:22422838)
GO_REF:0000033 		RGD
GO_Central		 PMID:22422838 PMID:25738458 GO_REF:0000033 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21054
    catalytic activity 6213
      catalytic activity, acting on a nucleic acid 677
        catalytic activity, acting on RNA 413
          catalytic activity, acting on a tRNA 140
            tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 21054
    catalytic activity 6213
      transferase activity 2477
        transferase activity, transferring sulphur-containing groups 82
          alkylthioltransferase activity 4
            methylthiotransferase activity 4
              tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity 1
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