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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:purinergic nucleotide receptor signaling pathway
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Accession:GO:0035590 term browser browse the term
Definition:The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: purinergic nucleotide receptor signalling pathway
 related_synonym: P2 receptor signaling pathway;   purinergic receptor signaling pathway;   purinergic receptor signalling pathway;   purinoceptor signaling pathway
 alt_id: GO:0035587


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purinergic nucleotide receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 involved_in IMP (PMID:25651887) UniProt PMID:25651887 NCBI chr12:45,216,095...45,440,404
Ensembl chr12:45,215,987...45,482,280 		JBrowse link
G CTSG cathepsin G involved_in TAS Reactome Reactome:R-HSA-9660826 NCBI chr14:24,573,518...24,576,250
Ensembl chr14:24,573,518...24,576,250 		JBrowse link
G P2RX1 purinergic receptor P2X 1 involved_in IEA GOC GO_REF:0000108 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G P2RX2 purinergic receptor P2X 2 involved_in IEA GOC GO_REF:0000108 NCBI chr12:132,618,776...132,622,388
Ensembl chr12:132,618,776...132,622,388 		JBrowse link
G P2RX3 purinergic receptor P2X 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:57,335,950...57,372,396
Ensembl chr11:57,338,352...57,372,396 		JBrowse link
G P2RX4 purinergic receptor P2X 4 involved_in IMP
IEA		 (PMID:11606481) BHF-UCL
GOC		 PMID:11606481 GO_REF:0000108 NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106 		JBrowse link
G P2RX5 purinergic receptor P2X 5 involved_in IEA GOC GO_REF:0000108 NCBI chr17:3,673,227...3,696,155
Ensembl chr17:3,672,199...3,696,240 		JBrowse link
G P2RX6 purinergic receptor P2X 6 involved_in IEA GOC GO_REF:0000108 NCBI chr22:21,009,799...21,028,008
Ensembl chr22:21,009,808...21,028,013 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in IEA
TAS
IMP		 (PMID:12151016)
(PMID:25651887)		 GOC
ARUK-UCL
UniProt		 PMID:12151016 PMID:25651887 GO_REF:0000108 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G protein-coupled adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY5 adenylate cyclase 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12223546) Ensembl
MGI		 PMID:12223546 GO_REF:0000107 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADORA1 adenosine A1 receptor involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G ADORA2A adenosine A2a receptor involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (MGI:80600|PMID:8738226), (PMID:12223546)
(PMID:10845921)
(PMID:12223546)		 RGD
TreeGrafter
MGI
GO_Central
InterPro
Ensembl		 PMID:8738226 PMID:10845921 PMID:12223546 PMID:12590138 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:80600 RGD:1625697 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ADORA2B adenosine A2b receptor involved_in IEA InterPro GO_REF:0000002 NCBI chr17:15,850,362...15,975,746
Ensembl chr17:15,945,130...15,975,746 		JBrowse link
G ADORA3 adenosine A3 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:12817016) InterPro
TreeGrafter
MGI
GO_Central		 PMID:12817016 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633 		JBrowse link
G GNAI2 G protein subunit alpha i2 involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:11923410 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:625670 NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362 		JBrowse link
G P2RY1 purinergic receptor P2Y1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439 		JBrowse link
G P2RY12 purinergic receptor P2Y12 involved_in ISO
IEA		 RGD
GOC		 PMID:12814667 GO_REF:0000108 RGD:6482299 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G protein-coupled purinergic nucleotide receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR171 G protein-coupled receptor 171 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:151,197,754...151,203,216
Ensembl chr 3:151,197,832...151,203,216 		JBrowse link
G GPR34 G protein-coupled receptor 34 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:41,688,973...41,697,275
Ensembl chr  X:41,688,973...41,697,275 		JBrowse link
G GPR87 G protein-coupled receptor 87 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:151,294,086...151,316,820
Ensembl chr 3:151,294,086...151,316,820 		JBrowse link
G P2RY1 purinergic receptor P2Y1 involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439 		JBrowse link
G P2RY11 purinergic receptor P2Y11 involved_in IEA GOC GO_REF:0000108 NCBI chr19:10,111,693...10,115,372
Ensembl chr19:10,111,693...10,115,372 		JBrowse link
G P2RY12 purinergic receptor P2Y12 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:151,336,843...151,384,753
Ensembl chr 3:151,336,843...151,384,753 		JBrowse link
G P2RY13 purinergic receptor P2Y13 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:151,326,312...151,329,549
Ensembl chr 3:151,326,312...151,329,549 		JBrowse link
G P2RY14 purinergic receptor P2Y14 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:151,212,117...151,278,542
Ensembl chr 3:151,212,117...151,278,542 		JBrowse link
G P2RY2 purinergic receptor P2Y2 involved_in IEA GOC GO_REF:0000108 NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427 		JBrowse link
G P2RY4 pyrimidinergic receptor P2Y4 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:70,258,166...70,260,204
Ensembl chr  X:70,258,166...70,260,204 		JBrowse link
G P2RY6 pyrimidinergic receptor P2Y6 involved_in IEA GOC GO_REF:0000108 NCBI chr11:73,264,506...73,298,625
Ensembl chr11:73,264,498...73,305,103 		JBrowse link
G P2RY8 P2Y receptor family member 8 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:1,462,581...1,537,185
NCBI chr  Y:1,462,581...1,537,185
Ensembl chr  Y:1,462,581...1,537,185
Ensembl chr  X:1,462,581...1,537,185 		JBrowse link
G PPAN-P2RY11 PPAN-P2RY11 readthrough involved_in IEA GOC GO_REF:0000108 NCBI chr19:10,106,362...10,115,372
Ensembl chr19:10,106,223...10,114,780 		JBrowse link
G PTAFR platelet activating factor receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936 		JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in IDA
IEA
IBA		 (PMID:16670267) UniProt
TreeGrafter
GO_Central		 PMID:16670267 GO_REF:0000033 GO_REF:0000118 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 involved_in IMP (PMID:18940592), (PMID:22389722) UniProt PMID:18940592 PMID:22389722 NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,302 		JBrowse link
G NECAB2 N-terminal EF-hand calcium binding protein 2 involved_in IDA (PMID:17689978) UniProt PMID:17689978 NCBI chr16:83,965,177...84,002,776
Ensembl chr16:83,968,244...84,002,776 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    cellular process 18300
      signal transduction 6573
        cell surface receptor signaling pathway 3201
          purinergic nucleotide receptor signaling pathway 32
            G protein-coupled purinergic nucleotide receptor signaling pathway 14
            G protein-coupled purinergic receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 19669
    biological regulation 13397
      regulation of biological process 13016
        signaling 7176
          signal transduction 6573
            cell surface receptor signaling pathway 3201
              purinergic nucleotide receptor signaling pathway 32
                G protein-coupled purinergic nucleotide receptor signaling pathway 14
                G protein-coupled purinergic receptor signaling pathway + 11
paths to the root