Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:sequestering of extracellular ligand from receptor
go back to main search page
Accession:GO:0035581 term browser browse the term
Definition:The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.
Comment:Preventing a ligand from binding to its cell surface receptor be achieved by binding to the ligand directly, or by binding to members of a ligand-containing complex.
Synonyms:exact_synonym: extracellular sequestering of receptor ligand
 related_synonym: negative regulation of protein bioavailability


show annotations for term's descendants           Sort by:
 
sequestering of extracellular ligand from receptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 antigen, complement regulatory protein involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:195,038,971...195,098,784
Ensembl chr 1:195,036,826...195,092,249
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:113,748,675...113,758,648
Ensembl chr 2:113,746,164...113,758,646
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5507937|PMID:23063586)
GO_Central
UniProt
PMID:21873635 PMID:23063586 MGI:5507937 MGI:6201960 NCBI chr 1:174,833,785...174,921,911
Ensembl chr 1:174,833,785...174,921,819
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:139,082,291...139,093,126
Ensembl chr 4:139,082,284...139,092,993
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in IDA
ISO
IBA
(MGI:1858315|PMID:10748465)
(MGI:6201960|PMID:21873635)
BHF-UCL
MGI
GO_Central
PMID:10748465 PMID:21873635 GO_REF:0000096 MGI:1858315 MGI:4834177 MGI:6201960 NCBI chr 4:82,881,751...82,885,151
Ensembl chr 4:82,881,751...82,885,148
JBrowse link
G Dand5 DAN domain family member 5, BMP antagonist involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:84,815,405...84,832,265
Ensembl chr 8:84,815,404...84,832,409
JBrowse link
G Fbn1 fibrillin 1 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr 2:125,300,594...125,506,485
Ensembl chr 2:125,300,594...125,507,993
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IDA (MGI:1203284|PMID:9660951) BHF-UCL PMID:9660951 MGI:1203284 NCBI chr 4:139,082,291...139,093,126
Ensembl chr 4:139,082,284...139,092,993
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain family member 5, BMP antagonist involved_in IDA (MGI:3055649|PMID:15466485) BHF-UCL PMID:15466485 MGI:3055649 NCBI chr 8:84,815,405...84,832,265
Ensembl chr 8:84,815,404...84,832,409
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr 2:125,300,594...125,506,485
Ensembl chr 2:125,300,594...125,507,993
JBrowse link
G Fbn2 fibrillin 2 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr18:58,008,623...58,210,572
Ensembl chr18:58,008,623...58,210,487
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:75,005,480...75,392,512
Ensembl chr17:75,005,568...75,392,512
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in IDA (MGI:6192878|PMID:29909984) UniProt PMID:29909984 MGI:6192878 NCBI chr16:32,142,785...32,165,594
Ensembl chr16:32,142,785...32,165,594
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28616
    cellular process 17619
      signal transduction 6515
        negative regulation of signal transduction 1288
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor 10
              sequestering of BMP from receptor via BMP binding 3
              sequestering of BMP in extracellular matrix 4
              sequestering of TGFbeta from receptor via TGFbeta binding 0
              sequestering of TGFbeta in extracellular matrix 4
              sequestering of nodal from receptor via nodal binding 1
Path 2
Term Annotations click to browse term
  biological_process 28616
    biological regulation 13270
      regulation of biological process 12618
        regulation of cellular process 12052
          signal transduction 6515
            regulation of signal transduction 2996
              extracellular regulation of signal transduction 11
                extracellular negative regulation of signal transduction 11
                  sequestering of extracellular ligand from receptor 10
                    sequestering of BMP from receptor via BMP binding 3
                    sequestering of BMP in extracellular matrix 4
                    sequestering of TGFbeta from receptor via TGFbeta binding 0
                    sequestering of TGFbeta in extracellular matrix 4
                    sequestering of nodal from receptor via nodal binding 1
paths to the root