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ONTOLOGY REPORT - ANNOTATIONS


Term:sequestering of extracellular ligand from receptor
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Accession:GO:0035581 term browser browse the term
Definition:The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.
Comment:Preventing a ligand from binding to its cell surface receptor be achieved by binding to the ligand directly, or by binding to members of a ligand-containing complex.
Synonyms:exact_synonym: extracellular sequestering of receptor ligand
 related_synonym: negative regulation of protein bioavailability


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sequestering of extracellular ligand from receptor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:23086448) RGD PMID:23086448 NCBI chr13:106,575,586...106,606,325 JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist involved_in IBA
ISO
PMID:21873635
(MGI:5507937|PMID:23063586)
RGD PMID:23063586 PMID:21873635 MGI:5507937, RGD:13792537 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in ISO
IEA
IBA
(PMID:23063586)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:23063586 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO
IBA
(PMID:9660951)
(MGI:1858315|PMID:10748465)
PMID:21873635
RGD PMID:9660951 PMID:10748465 PMID:21873635 MGI:1858315, RGD:13792537 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Dand5 DAN domain BMP antagonist family member 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist involved_in IEA
ISO
GO_REF:0000107
(MGI:1203284|PMID:9660951)
Ensembl
RGD
PMID:9660951 GO_REF:0000107 MGI:1203284 NCBI chr 5:151,318,752...151,329,948
Ensembl chr 5:151,318,754...151,338,719
JBrowse link
sequestering of nodal from receptor via nodal binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dand5 DAN domain BMP antagonist family member 5 involved_in ISO (MGI:3055649|PMID:15466485) RGD PMID:15466485 MGI:3055649 NCBI chr19:23,330,917...23,340,486
Ensembl chr19:23,334,164...23,339,589
JBrowse link
sequestering of TGFbeta in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) RGD PMID:20855508 MGI:4836762 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 involved_in ISO
ISS
(PMID:2022183), (PMID:8617200)
GO_REF:0000024
RGD
UniProt
PMID:2022183 PMID:8617200 GO_REF:0000024 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
ISO
GO_REF:0000024
(MGI:6192878|PMID:29909984)
UniProt
RGD
PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      signal transduction 6882
        negative regulation of signal transduction 1264
          extracellular negative regulation of signal transduction 11
            sequestering of extracellular ligand from receptor 10
              sequestering of BMP from receptor via BMP binding 3
              sequestering of BMP in extracellular matrix 4
              sequestering of TGFbeta from receptor via TGFbeta binding 0
              sequestering of TGFbeta in extracellular matrix 4
              sequestering of nodal from receptor via nodal binding 1
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12228
          signal transduction 6882
            regulation of signal transduction 2959
              extracellular regulation of signal transduction 11
                extracellular negative regulation of signal transduction 11
                  sequestering of extracellular ligand from receptor 10
                    sequestering of BMP from receptor via BMP binding 3
                    sequestering of BMP in extracellular matrix 4
                    sequestering of TGFbeta from receptor via TGFbeta binding 0
                    sequestering of TGFbeta in extracellular matrix 4
                    sequestering of nodal from receptor via nodal binding 1
paths to the root