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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA dealkylation
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Accession:GO:0035510 term browser browse the term
Definition:The removal of an alkyl group from one or more nucleotides within an DNA molecule.


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DNA dealkylation involved in DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO (PMID:18603530) RGD PMID:18603530 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase involved_in IBA
ISO
PMID:21873635
(PMID:18432238)
RGD PMID:18432238 PMID:21873635 RGD:13792537 NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914
JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase involved_in ISS
ISO
GO_REF:0000024
(PMID:16858410), (PMID:22055184)
UniProt
RGD
PMID:16858410 PMID:22055184 GO_REF:0000024 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000
JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 involved_in ISO
ISS
IEA
(PMID:22055184)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:22055184 GO_REF:0000024 GO_REF:0000107 NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:3817348|PMID:18775698)
(PMID:18775698), (PMID:20376003)
UniProt
Ensembl
RGD
PMID:18775698 PMID:20376003 GO_REF:0000024 GO_REF:0000107 MGI:3817348 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase acts_upstream_of_or_within IDA
ISO
(MGI:50172|PMID:1554415) RGD PMID:1554415 PMID:15025514 MGI:50172, RGD:2316914 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO
IBA
(PMID:21496894)
PMID:21873635
RGD PMID:21496894 PMID:21873635 RGD:13792537 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in ISO (PMID:18603530), (PMID:30017583), (PMID:30392959) RGD PMID:18603530 PMID:30017583 PMID:30392959 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Alkbh4 alkB homolog 4, lysine demethylase involved_in ISO (MGI:6323482|PMID:30982744) RGD PMID:30982744 MGI:6323482 NCBI chr12:20,524,030...20,529,947
Ensembl chr12:20,524,030...20,529,947
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:21496894)
UniProt
RGD
PMID:21496894 GO_REF:0000024 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5285126|PMID:21496894)
GO_REF:0000024
RGD
UniProt
PMID:21496894 PMID:21873635 GO_REF:0000024 MGI:5285126, RGD:13792537 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390
JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 involved_in ISO
IBA
(PMID:21496894)
PMID:21873635
RGD PMID:21496894 PMID:21873635 RGD:13792537 NCBI chr 9:12,564,955...12,578,461
Ensembl chr 9:12,564,920...12,578,458
JBrowse link
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase involved_in ISO (PMID:18775698)
(MGI:3817348|PMID:18775698), (MGI:4430814|PMID:17991826)
RGD PMID:17991826 PMID:18775698 MGI:3817348 MGI:4430814 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Tdg thymine-DNA glycosylase involved_in ISO (MGI:5141157|PMID:21722948), (MGI:5287540|PMID:21817016), (MGI:5487523|PMID:21278727) RGD PMID:21278727 PMID:21722948 PMID:21817016 MGI:5141157 MGI:5287540 MGI:5487523 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21496894)
(MGI:4822076|PMID:20639862)
(MGI:3844762|PMID:19372391), (MGI:5285126|PMID:21496894)
PMID:21873635
RGD PMID:19372391 PMID:20639862 PMID:21496894 PMID:21873635 MGI:3844762 MGI:4822076 MGI:5285126, RGD:13792537 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4822076|PMID:20639862)
(PMID:24315485)
RGD PMID:20639862 PMID:24315485 PMID:21873635 MGI:4822076, RGD:13792537 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534
JBrowse link
G Tet3 tet methylcytosine dioxygenase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5525037|PMID:23690950)
(MGI:4822076|PMID:20639862)
(MGI:5289702|PMID:21892189), (MGI:5432962|PMID:22722204), (MGI:5465527|PMID:21407207)
RGD PMID:20639862 PMID:21407207 PMID:21892189 PMID:22722204 PMID:23690950 More... MGI:4822076 MGI:5289702 MGI:5432962 MGI:5465527 MGI:5525037, RGD:13792537 NCBI chr 4:115,867,412...115,964,433
Ensembl chr 4:115,871,265...115,964,193
JBrowse link
negative regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07015759.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07017902.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr15:27,225,434...27,225,910 JBrowse link
G AABR07026842.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07058017.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07061871.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Dppa3 developmental pluripotency-associated 3 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267), (MGI:5465527|PMID:21407207)
PMID:21873635
UniProt
RGD
PMID:17143267 PMID:21407207 PMID:22722204 PMID:21873635 GO_REF:0000024 MGI:5432962 MGI:5447615 MGI:5465527, RGD:13792537 NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
JBrowse link
G Dppa3l1 developmental pluripotency associated 3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:56,421,825...56,422,277
Ensembl chr 8:56,421,825...56,422,277
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:3046385|PMID:15087456) RGD PMID:15087456 MGI:3046385 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G LOC679766 similar to developmental pluripotency-associated 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Trim28 tripartite motif-containing 28 acts_upstream_of_or_within ISO MGI:1928907 (MGI:5319411|PMID:22495301) RGD PMID:22495301 MGI:5319411 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
oxidative DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase involved_in ISO
IBA
(PMID:18432238)
PMID:21873635
RGD PMID:18432238 PMID:21873635 RGD:13792537 NCBI chr12:42,494,187...42,500,929
Ensembl chr12:42,496,300...42,500,914
JBrowse link
G Alkbh4 alkB homolog 4, lysine demethylase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:20,524,030...20,529,947
Ensembl chr12:20,524,030...20,529,947
JBrowse link
oxidative single-stranded DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alkbh1 alkB homolog 1, histone H2A dioxygenase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759
JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase involved_in ISO
ISS
(PMID:16858410), (PMID:22055184)
GO_REF:0000024
RGD
UniProt
PMID:16858410 PMID:22055184 GO_REF:0000024 NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase involved_in IBA
IEA
ISO
ISS
PMID:21873635
GO_REF:0000107
(MGI:3817348|PMID:18775698)
(PMID:18775698), (PMID:20376003)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18775698 PMID:20376003 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3817348, RGD:13792537 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
positive regulation of DNA demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otud4 OTU deubiquitinase 4 involved_in ISO (PMID:25944111) RGD PMID:25944111 NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815
JBrowse link
G Stpg4 sperm-tail PG-rich repeat containing 4 involved_in IBA
ISO
PMID:21873635
(MGI:5762940|PMID:23560077)
RGD PMID:23560077 PMID:21873635 MGI:5762940, RGD:13792537 NCBI chr 6:7,108,827...7,158,519
Ensembl chr 6:7,108,869...7,151,390
JBrowse link
G Tox thymocyte selection-associated high mobility group box involved_in ISO (MGI:3045816|PMID:15078895) RGD PMID:15078895 MGI:3045816 NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272
JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25944111)
UniProt
Ensembl
RGD
PMID:25944111 GO_REF:0000024 GO_REF:0000107 NCBI chr10:6,880,684...6,925,033
Ensembl chr10:6,828,795...6,925,355
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:25944111) RGD PMID:25944111 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      organic substance metabolic process 11337
        macromolecule metabolic process 9793
          macromolecule modification 3814
            DNA modification 108
              DNA dealkylation 31
                DNA dealkylation involved in DNA repair 6
                DNA demethylation + 29
Path 2
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11797
      cellular metabolic process 10717
        cellular nitrogen compound metabolic process 6561
          nucleobase-containing compound metabolic process 5378
            nucleic acid metabolic process 4888
              DNA metabolic process 883
                DNA modification 108
                  DNA dealkylation 31
                    DNA dealkylation involved in DNA repair 6
                    DNA demethylation + 29
paths to the root