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ONTOLOGY REPORT - ANNOTATIONS

Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acly ATP citrate lyase involved_in NAS
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:1371749)
GO_REF:0000002		 GO_Central
Ensembl
RGD
InterPro		 PMID:1371749 PMID:2295639 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:631761 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:16788062)
(PMID:11150295)
GO_REF:0000033		 RGD
GO_Central		 PMID:11150295 PMID:16788062 GO_REF:0000033 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:11150295)		 GO_Central
RGD		 PMID:11150295 GO_REF:0000033 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A involved_in ISO (PMID:30672040) RGD PMID:30672040 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Mlycd malonyl-CoA decarboxylase involved_in IDA
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000041
(PMID:10417274), (PMID:10455107), (PMID:9869665)		 GO_Central
UniProt
RGD		 PMID:9869665 PMID:10417274 PMID:10455107 PMID:17316539 GO_REF:0000033 GO_REF:0000041, RGD:1600790 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO (PMID:29754768) RGD PMID:29754768 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325 		JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase involved_in IDA
ISO
IBA
IEA		 MGI:2386703 (PMID:17314311), (PMID:27621431)
GO_REF:0000033
GO_REF:0000002
(PMID:24534072)		 RGD
GO_Central
InterPro		 PMID:17314311 PMID:24534072 PMID:27621431 PMID:7487891 GO_REF:0000002 GO_REF:0000033, RGD:1599112 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
Ensembl chr 1:50,978,051...51,004,479 		JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in IDA
ISO		 MGI:2386703 (PMID:17314311), (PMID:27621431)
(PMID:24534072)		 RGD PMID:17314311 PMID:24534072 PMID:27621431 PMID:7487891 RGD:1599112 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558) RGD PMID:22628558 NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:22628558)
MGI:5635078 (PMID:22628558), (PMID:24910426)		 RGD PMID:22628558 PMID:24910426 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IEA		 MGI:2182095|MGI:2386703 (PMID:18586888)
GO_REF:0000033
GO_REF:0000114
(PMID:19081061), (PMID:24534072)
GO_REF:0000002		 RGD
GO_Central
ComplexPortal
InterPro		 PMID:18586888 PMID:19081061 PMID:24534072 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000114, RGD:1599112 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311 		JBrowse link
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:82,511,483...82,514,378
Ensembl chr16:82,511,511...82,514,372 		JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:7487891 GO_REF:0000033, RGD:1599112 NCBI chr 2:229,872,300...229,873,848 JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta involved_in IDA
IBA
ISO
IEA		 GO_REF:0000033
GO_REF:0000114
GO_REF:0000002
(PMID:19081061), (PMID:24534072)
GO_REF:0000107		 GO_Central
ComplexPortal
InterPro
RGD
Ensembl		 PMID:19081061 PMID:24534072 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114, RGD:1599112 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X involved_in ISO (PMID:24534072)
MGI:2386703 (PMID:17314311), (PMID:27621431)		 RGD PMID:17314311 PMID:24534072 PMID:27621431 NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 TAS RGD PMID:12435272 RGD:729541 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcdh glutaryl-CoA dehydrogenase involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:6895440 GO_REF:0000033, RGD:1598697 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in IGI
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16466685 GO_REF:0000033, RGD:2312800 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 IGI RGD PMID:16466685 RGD:2312800 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in IGI
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16466685 GO_REF:0000033, RGD:2312800 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 involved_in IGI
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:16466685 GO_REF:0000033, RGD:2312800 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta involved_in IEA
ISO		 GO_REF:0000041
(PMID:18487439)		 UniProt
RGD		 PMID:18487439 GO_REF:0000041 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgk1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) RGD PMID:26942675 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdk branched chain ketoacid dehydrogenase kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:22195962)		 Ensembl
GO_Central
RGD		 PMID:22195962 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:22360721)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:22360721 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO
IBA		 (PMID:22865452)
GO_REF:0000033		 RGD
GO_Central		 PMID:22865452 GO_REF:0000033 NCBI chr  X:58,486,699...58,553,533
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO
IBA
IEA
ISS		 (PMID:21852536)
GO_REF:0000033
(PMID:16606348)
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:16606348 PMID:21852536 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 involved_in ISO (PMID:38547260) RGD PMID:38547260 NCBI chr 4:72,170,134...72,557,707
Ensembl chr 4:72,170,134...72,557,694 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO MGI:2389489 (PMID:16636270), (PMID:16734431) RGD PMID:16636270 PMID:16734431 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmut methylmalonyl-CoA mutase involved_in ISO (PMID:7904153) RGD PMID:7904153 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        sulfur compound metabolic process 342
          thioester metabolic process 97
            thioester biosynthetic process 38
              acyl-CoA biosynthetic process + 38
paths to the root