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ONTOLOGY REPORT - ANNOTATIONS

Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:36,525,266...36,545,634
Ensembl chr 9:36,525,261...36,545,633 		JBrowse link
G ACLY ATP citrate lyase involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr12:20,796,678...20,841,301
Ensembl chr12:20,796,749...20,841,298 		JBrowse link
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11150295) Ensembl
MGI
GO_Central		 PMID:11150295 GO_REF:0000033 GO_REF:0000107 NCBI chr17:30,800,536...30,839,799
Ensembl chr17:30,800,427...30,839,742 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:11150295) GO_Central
MGI		 PMID:11150295 GO_REF:0000033 NCBI chr17:38,260,152...38,315,764
Ensembl chr17:38,260,147...38,315,757 		JBrowse link
G DIP2A disco interacting protein 2 homolog A involved_in ISO (PMID:30672040) UniProt PMID:30672040
G MLYCD malonyl-CoA decarboxylase involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:17316539 GO_REF:0000033 GO_REF:0000107 RGD:1600790 NCBI chr 6:4,683,386...4,698,698
Ensembl chr 6:4,681,664...4,698,661 		JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,833,945...168,876,831
Ensembl chr 6:168,870,869...168,876,779 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:30,800,536...30,839,799
Ensembl chr17:30,800,427...30,839,742 		JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLAT dihydrolipoamide S-acetyltransferase involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl
InterPro		 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1599112 NCBI chr 9:39,738,639...39,763,813
Ensembl chr 9:39,738,564...39,796,806 		JBrowse link
G DLD dihydrolipoamide dehydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:7487891 GO_REF:0000107 RGD:1599112 NCBI chr 9:107,642,129...107,668,443
Ensembl chr 9:107,642,095...107,673,583 		JBrowse link
G MPC1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558) MGI PMID:22628558 NCBI chr 1:2,541,475...2,552,864 JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910426)
(PMID:22628558)		 Ensembl
MGI		 PMID:22628558 PMID:24910426 GO_REF:0000107 NCBI chr 4:83,069,914...83,091,687
Ensembl chr 4:83,069,748...83,096,990 		JBrowse link
G OLFML3 olfactomedin like 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 4:106,566,978...106,571,086
Ensembl chr 4:106,563,450...106,569,771 		JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA
ISS		 (PMID:18586888) RGD
MGI
GO_Central
Ensembl
InterPro
UniProt		 PMID:7487891 PMID:18586888 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 RGD:1599112 NCBI chr  X:15,699,924...15,718,908
Ensembl chr  X:15,700,050...15,718,903 		JBrowse link
G PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 ISO RGD PMID:7487891 RGD:1599112 NCBI chr 8:123,926,253...123,927,419 JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta involved_in ISO
IBA
IEA		 RGD
GO_Central
InterPro
Ensembl		 PMID:7487891 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1599112 NCBI chr13:40,161,519...40,167,502
Ensembl chr13:40,160,568...40,167,476 		JBrowse link
G PDHX pyruvate dehydrogenase complex component X involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:26,014,954...26,094,895
Ensembl chr 2:26,014,970...26,103,402 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCDH glutaryl-CoA dehydrogenase involved_in ISO
IBA		 RGD
GO_Central		 PMID:6895440 GO_REF:0000033 RGD:1598697 NCBI chr 2:66,131,154...66,138,963
Ensembl chr 2:66,130,625...66,138,868 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 involved_in ISO
IBA		 RGD
GO_Central		 PMID:16466685 GO_REF:0000033 RGD:2312800 NCBI chr15:45,866,858...45,936,327
Ensembl chr15:45,866,857...45,963,729 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:89,760,863...89,838,103
Ensembl chr  X:89,760,866...89,806,274 		JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 involved_in ISO
IBA		 RGD
GO_Central		 PMID:16466685 GO_REF:0000033 RGD:2312800 NCBI chr14:122,777,135...122,828,054
Ensembl chr14:122,777,130...122,828,052 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 involved_in ISO
IBA		 RGD
GO_Central		 PMID:16466685 GO_REF:0000033 RGD:2312800 NCBI chr 2:134,210,915...134,278,860
Ensembl chr 2:134,210,917...134,278,820 		JBrowse link
G DEPDC1B DEP domain containing 1B involved_in IEA UniProt GO_REF:0000104 NCBI chr16:39,466,496...39,558,750
Ensembl chr16:39,466,497...39,557,840 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:167,881,357...167,886,125
Ensembl chr 6:167,881,352...167,886,124 		JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 involved_in IEA UniProt GO_REF:0000104 NCBI chr14:113,226,589...113,230,038
Ensembl chr14:113,226,621...113,230,208 		JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 involved_in IEA UniProt GO_REF:0000104 NCBI chr 1:86,163,845...86,196,036
Ensembl chr 1:86,163,868...86,195,987 		JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 involved_in IEA UniProt GO_REF:0000104 NCBI chr 7:46,860,768...46,932,945
Ensembl chr 7:46,860,770...46,932,926 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 involved_in IEA UniProt GO_REF:0000104 NCBI chr 8:112,038,670...112,190,079
Ensembl chr 8:112,027,054...112,191,274 		JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA UniProt GO_REF:0000104 NCBI chr16:39,588,122...39,680,273
Ensembl chr16:39,588,129...39,680,173 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha involved_in IEA UniProt GO_REF:0000041 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G ACACB acetyl-CoA carboxylase beta involved_in IEA UniProt
Ensembl		 GO_REF:0000041 GO_REF:0000107 NCBI chr14:41,621,574...41,739,916
Ensembl chr14:41,621,574...41,739,916 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) UniProt PMID:26942675 NCBI chr  X:62,187,472...62,210,321
Ensembl chr  X:62,187,434...62,210,705 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:36,525,266...36,545,634
Ensembl chr 9:36,525,261...36,545,633 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCKDK branched chain keto acid dehydrogenase kinase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:17,375,628...17,380,925
Ensembl chr 3:17,375,354...17,380,880 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:78,608,394...78,650,958
Ensembl chr15:78,608,432...78,652,962 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,274,562...26,295,787
Ensembl chr12:26,274,606...26,301,878 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:20,486,205...20,598,492
Ensembl chr  X:20,486,341...20,602,664 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:75,246,956...75,260,134
Ensembl chr 9:75,246,002...75,260,134 		JBrowse link
G TPK1 thiamin pyrophosphokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:112,931,370...113,305,178
Ensembl chr 9:112,931,795...113,305,175 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16734431)
(PMID:16636270)		 Ensembl
MGI		 PMID:16636270 PMID:16734431 GO_REF:0000107 NCBI chr 8:129,247,724...129,388,307
Ensembl chr 8:129,248,819...129,271,128 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMUT methylmalonyl-CoA mutase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,597,313...43,624,603
Ensembl chr 7:43,597,246...43,624,671 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17668
    cellular process 17206
      metabolic process 10557
        sulfur compound metabolic process 317
          thioester metabolic process 94
            thioester biosynthetic process 39
              acyl-CoA biosynthetic process + 39
paths to the root