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ONTOLOGY REPORT - ANNOTATIONS

Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-Coenzyme A acetyltransferase 1 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
G Acly ATP citrate lyase involved_in IBA
ISS
ISO		 GO_Central
BHF-UCL		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826 		JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 acts_upstream_of_or_within
involved_in		 IDA
IBA
ISO
ISS		 (PMID:11150295) MGI
GO_Central
UniProt		 PMID:11150295 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 2:150,460,031...150,510,160
Ensembl chr 2:150,460,025...150,510,420 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:11150295) MGI
GO_Central		 PMID:11150295 GO_REF:0000033 NCBI chr 2:155,359,963...155,404,663
Ensembl chr 2:155,359,868...155,427,644 		JBrowse link
G Dip2a disco interacting protein 2 homolog A involved_in IDA (PMID:30672040) UniProt PMID:30672040 NCBI chr10:76,098,581...76,181,194
Ensembl chr10:76,095,263...76,181,125 		JBrowse link
G Mlycd malonyl-CoA decarboxylase involved_in ISO
IBA
ISS
IEA		 RGD
GO_Central
UniProt		 PMID:17316539 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000096 GO_REF:0000119 RGD:1600790 NCBI chr 8:120,121,591...120,148,577
Ensembl chr 8:120,121,617...120,137,841 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:119,275,724...119,279,673
Ensembl chr 4:119,275,727...119,279,617 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss1 acyl-CoA synthetase short-chain family member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:150,460,031...150,510,160
Ensembl chr 2:150,460,025...150,510,420 		JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase involved_in
acts_upstream_of_or_within		 ISO
IBA
IMP
IC		 (PMID:27621431)
(PMID:17314311)
(PMID:12108679)		 RGD
GO_Central
MGI		 PMID:7487891 PMID:12108679 PMID:17314311 PMID:27621431 GO_REF:0000008 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:1599112 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080 		JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in
acts_upstream_of_or_within		 ISO
IMP
IC		 (PMID:17314311)
(PMID:27621431)
(PMID:9405644)		 RGD
GO_Central
MGI		 PMID:7487891 PMID:9405644 PMID:17314311 PMID:27621431 GO_REF:0000008 GO_REF:0000096 GO_REF:0000119 RGD:1599112 NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 IMP
IC		 (PMID:22628558)
(PMID:22628554)		 MGI PMID:22628554 PMID:22628558 NCBI chr17:8,502,590...8,516,499
Ensembl chr17:8,501,736...8,516,493 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within
involved_in		 IMP (PMID:24910426)
(PMID:22628558)		 MGI PMID:22628558 PMID:24910426 NCBI chr 1:165,288,829...165,308,787
Ensembl chr 1:165,288,206...165,308,783 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 alpha 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS
IMP		 (PMID:18586888) RGD
GO_Central
UniProt
ComplexPortal
MGI		 PMID:7487891 PMID:18586888 GO_REF:0000024 GO_REF:0000033 GO_REF:0000114 GO_REF:0000119 RGD:1599112 NCBI chr  X:158,905,215...158,921,426
Ensembl chr  X:158,905,205...158,921,409 		JBrowse link
G Pdha2 pyruvate dehydrogenase E1 alpha 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 RGD
GO_Central
MGI		 PMID:7487891 GO_REF:0000008 GO_REF:0000033 GO_REF:0000096 RGD:1599112 NCBI chr 3:140,915,765...140,918,116
Ensembl chr 3:140,915,765...140,918,116 		JBrowse link
G Pdhb pyruvate dehydrogenase (lipoamide) beta involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS		 RGD
GO_Central
ComplexPortal
UniProt
MGI		 PMID:7487891 GO_REF:0000008 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000114 GO_REF:0000119 RGD:1599112 NCBI chr14:14,296,470...14,303,782
Ensembl chr14:14,296,748...14,303,777 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X acts_upstream_of_or_within
involved_in		 ISO
IMP		 (PMID:17314311)
(PMID:27621431)		 MGI
GO_Central		 PMID:17314311 PMID:27621431 GO_REF:0000008 GO_REF:0000119 NCBI chr 2:102,851,400...102,903,858
Ensembl chr 2:102,851,420...102,903,858 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:8726225) MGI PMID:8726225 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcdh glutaryl-Coenzyme A dehydrogenase involved_in ISO
IBA		 RGD
GO_Central		 PMID:6895440 GO_REF:0000033 GO_REF:0000096 RGD:1598697 NCBI chr 8:85,613,016...85,629,378
Ensembl chr 8:85,613,022...85,620,550 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:16466685 GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 RGD:2312800 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 involved_in ISO RGD
GO_Central		 PMID:16466685 GO_REF:0000096 RGD:2312800 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in ISO
IBA		 RGD
GO_Central		 PMID:16466685 GO_REF:0000033 GO_REF:0000096 RGD:2312800 NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152 		JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 involved_in ISO
IBA		 RGD
GO_Central		 PMID:16466685 GO_REF:0000033 GO_REF:0000096 RGD:2312800 NCBI chr11:54,194,580...54,255,582
Ensembl chr11:54,194,624...54,255,582 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:118,285,321...118,290,150
Ensembl chr 4:118,285,290...118,290,150 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 involved_in IEA UniProt GO_REF:0000104 NCBI chr19:46,120,336...46,124,133
Ensembl chr19:46,120,336...46,124,133 		JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 involved_in IEA UniProt GO_REF:0000104 NCBI chr 9:83,660,745...83,688,358
Ensembl chr 9:83,660,745...83,688,330 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 involved_in IEA UniProt GO_REF:0000104 NCBI chr 9:77,824,647...77,891,801
Ensembl chr 9:77,824,646...77,891,801 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 involved_in IEA UniProt GO_REF:0000104 NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 involved_in IEA UniProt GO_REF:0000104 NCBI chr13:108,350,860...108,423,643
Ensembl chr13:108,350,938...108,422,217 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-Coenzyme A carboxylase alpha involved_in IEA UniProt GO_REF:0000041 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477 		JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta involved_in IMP
IEA		 (PMID:18487439) UniProt PMID:18487439 GO_REF:0000041 NCBI chr 5:114,284,748...114,388,822
Ensembl chr 5:114,284,596...114,388,822 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgk1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) UniProt PMID:26942675 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-Coenzyme A acetyltransferase 1 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bckdk branched chain ketoacid dehydrogenase kinase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:127,503,245...127,508,836
Ensembl chr 7:127,503,254...127,509,393 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 involved_in IMP
IBA		 (PMID:22195962) UniProt
GO_Central		 PMID:22195962 GO_REF:0000033 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase, isoenzyme 2 involved_in IMP
IBA		 (PMID:22360721) UniProt
GO_Central		 PMID:22360721 GO_REF:0000033 NCBI chr11:94,917,084...94,932,197
Ensembl chr11:94,917,084...94,932,180 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase, isoenzyme 3 involved_in ISS
IBA
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr  X:92,798,923...92,875,756
Ensembl chr  X:92,808,213...92,875,807 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 acts_upstream_of_or_within
involved_in		 TAS
IBA
ISO
IMP		 (PMID:10548532)
(PMID:16606348)		 MGI
GO_Central
UniProt		 PMID:10548532 PMID:16606348 GO_REF:0000033 GO_REF:0000119 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309 		JBrowse link
G Tpk1 thiamine pyrophosphokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,316,510...43,644,726
Ensembl chr 6:43,321,935...43,643,212 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein, alpha acts_upstream_of_or_within IMP
IDA		 (PMID:16636270)
(PMID:16734431)		 MGI PMID:16636270 PMID:16734431 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmut methylmalonyl-Coenzyme A mutase involved_in IDA (PMID:7904153) MGI PMID:7904153 NCBI chr17:41,245,576...41,272,880
Ensembl chr17:41,245,576...41,272,879 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      metabolic process 11662
        sulfur compound metabolic process 361
          thioester metabolic process 101
            thioester biosynthetic process 38
              acyl-CoA biosynthetic process + 38
paths to the root