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ONTOLOGY REPORT - ANNOTATIONS

Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis

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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:99,552,760...99,580,079
Ensembl chr 1:99,552,838...99,579,914 		JBrowse link
G ACLY ATP citrate lyase involved_in ISO (PMID:1371749) BHF-UCL PMID:1371749 NCBI chr16:64,343,175...64,392,011 JBrowse link
G ACLY ATP citrate lyase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 Ensembl chr16:64,333,207...64,373,230 JBrowse link
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in ISO (PMID:16788062) UniProt PMID:16788062
G ACSS2 acyl-CoA synthetase short chain family member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11150295) MGI
TreeGrafter		 PMID:11150295 GO_REF:0000118 NCBI chr 2:39,181,446...39,230,164
Ensembl chr 2:39,181,468...39,229,444 		JBrowse link
G DIP2A disco interacting protein 2 homolog A involved_in ISO (PMID:30672040) UniProt PMID:30672040 NCBI chr 2:90,058,331...90,167,278
Ensembl chr 2:90,059,346...90,167,019 		JBrowse link
G LOC103247057 acyl-CoA synthetase short chain family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11150295) MGI
Ensembl
TreeGrafter		 PMID:11150295 GO_REF:0000107 GO_REF:0000118
G MLYCD malonyl-CoA decarboxylase involved_in ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:17316539 GO_REF:0000107 GO_REF:0000118 RGD:1600790 NCBI chr 5:69,312,978...69,329,346
Ensembl chr 5:69,313,062...69,329,102 		JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr20:90,467,656...90,473,704 JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLAT dihydrolipoamide S-acetyltransferase involved_in ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:7487891 GO_REF:0000002 GO_REF:0000118 RGD:1599112 NCBI chr 1:103,379,165...103,419,585
Ensembl chr 1:103,380,426...103,420,386 		JBrowse link
G DLD dihydrolipoamide dehydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:7487891 GO_REF:0000107 RGD:1599112 NCBI chr21:76,795,573...76,825,504
Ensembl chr21:76,795,592...76,824,923 		JBrowse link
G LOC103222041 dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial-like involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 4:56,991,325...56,993,626 JBrowse link
G MPC1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558) MGI PMID:22628558 NCBI chr13:94,080,417...94,100,149 JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:22628558)
(PMID:24910426)		 MGI PMID:22628558 PMID:24910426 NCBI chr25:61,109,742...61,128,675 JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:18586888)
(PMID:19081061), (PMID:24534072)		 RGD
MGI
ComplexPortal		 PMID:7487891 PMID:18586888 PMID:19081061 PMID:24534072 RGD:1599112 NCBI chr  X:17,804,123...17,820,087 JBrowse link
G PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 involved_in ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:7487891 GO_REF:0000002 GO_REF:0000118 RGD:1599112 NCBI chr 7:44,056,991...44,058,705
Ensembl chr 7:44,057,352...44,058,518 		JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta involved_in ISO
IEA		 RGD
TreeGrafter
InterPro
Ensembl		 PMID:7487891 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1599112 NCBI chr22:19,718,610...19,725,037
Ensembl chr22:19,718,353...19,725,036 		JBrowse link
G PDHX pyruvate dehydrogenase complex component X involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:30,270,567...30,344,929
Ensembl chr 1:30,269,957...30,344,494 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCDH glutaryl-CoA dehydrogenase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:6895440 GO_REF:0000118 RGD:1598697 NCBI chr 6:11,572,512...11,588,108
Ensembl chr 6:11,572,540...11,588,224 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 7:130,712,633...130,783,360
Ensembl chr 7:130,712,308...130,763,756 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:97,488,414...97,575,251 JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:16466685 GO_REF:0000118 RGD:2312800 NCBI chr 9:105,259,546...105,311,500
Ensembl chr 9:105,257,429...105,311,690 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chr23:34,787,097...34,846,387
Ensembl chr23:34,787,432...34,829,042 		JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 involved_in IEA UniProt GO_REF:0000104 NCBI chr 9:95,260,674...95,265,682
Ensembl chr 9:95,262,342...95,265,350 		JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 involved_in IEA UniProt GO_REF:0000104 NCBI chr13:4,652,674...4,687,308
Ensembl chr13:4,652,677...4,687,294 		JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 involved_in IEA UniProt GO_REF:0000104 NCBI chr17:19,227,209...19,305,789
Ensembl chr17:19,277,593...19,307,625 		JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:56,934,631...57,026,749
Ensembl chr 4:56,934,645...56,965,285 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha involved_in IEA UniProt GO_REF:0000041 NCBI chr16:30,374,166...30,704,635
Ensembl chr16:30,452,343...30,705,004 		JBrowse link
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl
UniProt		 GO_REF:0000041 GO_REF:0000107 NCBI chr11:104,325,250...104,488,567
Ensembl chr11:104,349,573...104,488,003 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) UniProt PMID:26942675 NCBI chr  X:67,072,029...67,093,881 JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:99,552,760...99,580,079
Ensembl chr 1:99,552,838...99,579,914 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:58,055,508...58,168,505
Ensembl chr10:58,055,511...58,096,774 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:43,227,843...43,243,596
Ensembl chr16:43,229,093...43,243,627 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:22,948,162...23,030,542
Ensembl chr  X:22,948,203...23,029,868 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:53,445,607...53,458,729
Ensembl chr21:53,445,457...53,460,776 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16734431)
(PMID:16636270)		 Ensembl
MGI		 PMID:16636270 PMID:16734431 GO_REF:0000107 NCBI chr 7:38,083,154...38,194,068
Ensembl chr 7:38,081,509...38,191,479 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMUT methylmalonyl-CoA mutase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:22,922,262...22,957,742
Ensembl chr17:22,922,307...22,957,879 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17043
    cellular process 16562
      metabolic process 10934
        sulfur compound metabolic process 326
          thioester metabolic process 87
            thioester biosynthetic process 36
              acyl-CoA biosynthetic process + 36
paths to the root