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ONTOLOGY REPORT - ANNOTATIONS

Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:24,361,301...24,379,807
Ensembl chr 5:24,361,301...24,379,812 		JBrowse link
G ACLY ATP citrate lyase involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:20,929,530...20,974,200
Ensembl chr 9:20,929,614...20,973,663 		JBrowse link
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11150295) Ensembl
MGI		 PMID:11150295 GO_REF:0000107 NCBI chr23:1,192,771...1,251,724
Ensembl chr23:1,184,392...1,252,255 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 acts_upstream_of_or_within ISO (PMID:11150295) MGI PMID:11150295 NCBI chr24:23,928,800...23,973,383
Ensembl chr24:23,928,838...23,972,651 		JBrowse link
G DIP2A disco interacting protein 2 homolog A involved_in ISO (PMID:30672040) UniProt PMID:30672040 NCBI chr31:39,695,620...39,778,527
Ensembl chr31:39,686,465...39,777,484 		JBrowse link
G MLYCD malonyl-CoA decarboxylase involved_in ISO
IEA		 RGD
Ensembl		 PMID:17316539 GO_REF:0000107 RGD:1600790 NCBI chr 5:68,385,058...68,399,965
Ensembl chr 5:68,384,618...68,399,965 		JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:813,435...817,732
Ensembl chr15:813,870...816,825 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr23:1,192,771...1,251,724
Ensembl chr23:1,184,392...1,252,255 		JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLAT dihydrolipoamide S-acetyltransferase involved_in ISO
IEA		 RGD
Ensembl
InterPro		 PMID:7487891 GO_REF:0000002 GO_REF:0000107 RGD:1599112 NCBI chr 5:21,062,833...21,094,235
Ensembl chr 5:21,064,026...21,094,153 		JBrowse link
G DLD dihydrolipoamide dehydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:7487891 GO_REF:0000107 RGD:1599112 NCBI chr18:12,703,340...12,734,408
Ensembl chr18:12,703,341...12,734,479 		JBrowse link
G LOC119879505 pyruvate dehydrogenase E1 component subunit beta, mitochondrial-like involved_in IEA InterPro GO_REF:0000002
G MPC1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558) MGI PMID:22628558 NCBI chr 1:54,379,195...54,395,697 JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558)
(PMID:24910426)		 MGI PMID:22628558 PMID:24910426 NCBI chr 7:30,544,986...30,574,102
Ensembl chr 7:30,545,152...30,574,080 		JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (PMID:18586888) RGD
MGI
Ensembl
InterPro
UniProt		 PMID:7487891 PMID:18586888 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 RGD:1599112 NCBI chr  X:15,338,364...15,354,011
Ensembl chr  X:15,338,202...15,387,458 		JBrowse link
G PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 ISO RGD PMID:7487891 RGD:1599112
G PDHB pyruvate dehydrogenase E1 subunit beta involved_in ISO
IEA		 RGD
InterPro		 PMID:7487891 GO_REF:0000002 RGD:1599112 NCBI chr20:32,185,420...32,191,592 JBrowse link
G PDHX pyruvate dehydrogenase complex component X involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr18:32,947,883...33,011,845
Ensembl chr18:32,917,858...33,011,819 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCDH glutaryl-CoA dehydrogenase ISO RGD PMID:6895440 RGD:1598697 NCBI chr20:49,284,341...49,290,456
Ensembl chr20:49,284,425...49,290,849 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chr16:45,735,675...45,806,235
Ensembl chr16:45,735,703...45,804,970 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:82,864,506...82,943,984
Ensembl chr  X:82,866,823...82,916,789 		JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16466685 RGD:2312800 NCBI chr28:23,437,838...23,478,763
Ensembl chr28:23,440,387...23,478,762 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chr11:20,226,877...20,284,919
Ensembl chr11:20,227,268...20,285,631 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr15:16,798,305...16,803,071
Ensembl chr15:16,798,370...16,802,899 		JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 involved_in IEA UniProt GO_REF:0000104 NCBI chr28:14,756,019...14,759,893
Ensembl chr28:14,756,653...14,759,580 		JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 involved_in IEA UniProt GO_REF:0000104 NCBI chr12:40,845,357...40,876,658
Ensembl chr12:40,846,202...40,876,758 		JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 involved_in IEA UniProt GO_REF:0000104 NCBI chr12:20,732,641...20,807,748
Ensembl chr12:20,734,282...20,807,739 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 involved_in IEA UniProt GO_REF:0000104 NCBI chr32:30,221,858...30,360,761
Ensembl chr32:30,224,252...30,360,138 		JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA UniProt GO_REF:0000104 NCBI chr 2:47,406,323...47,482,113
Ensembl chr 2:47,296,656...47,482,064 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha involved_in IEA UniProt GO_REF:0000041 NCBI chr 9:36,904,204...37,188,096
Ensembl chr 9:36,905,293...37,187,892 		JBrowse link
G ACACB acetyl-CoA carboxylase beta involved_in IEA UniProt
Ensembl		 GO_REF:0000041 GO_REF:0000107 NCBI chr26:17,763,531...17,895,319
Ensembl chr26:17,747,362...17,894,400 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) UniProt PMID:26942675 NCBI chr  X:60,374,743...60,396,244
Ensembl chr  X:60,374,754...60,423,947 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:24,361,301...24,379,807
Ensembl chr 5:24,361,301...24,379,812 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:16,918,329...16,944,532
Ensembl chr36:16,918,058...16,944,620 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,099,457...26,116,094
Ensembl chr 9:26,100,343...26,115,423 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:19,994,383...20,058,979
Ensembl chr  X:19,994,393...20,058,485 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,825,861...20,839,290
Ensembl chr14:20,827,831...20,839,256 		JBrowse link
G TPK1 thiamin pyrophosphokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:5,257,749...5,588,179
Ensembl chr16:5,257,205...5,636,153 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16636270)
(PMID:16734431)		 MGI
Ensembl		 PMID:16636270 PMID:16734431 GO_REF:0000107 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMUT methylmalonyl-CoA mutase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:17,306,074...17,339,921
Ensembl chr12:17,307,522...17,339,897 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17099
    cellular process 16593
      metabolic process 10707
        sulfur compound metabolic process 306
          thioester metabolic process 85
            thioester biosynthetic process 37
              acyl-CoA biosynthetic process + 37
paths to the root