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ONTOLOGY REPORT - ANNOTATIONS


Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) BHF-UCL PMID:17371050 NCBI chrNW_004955412:10,350,088...10,369,806
Ensembl chrNW_004955412:10,349,593...10,369,806
JBrowse link
G Acly ATP citrate lyase involved_in ISO (PMID:1371749) BHF-UCL PMID:1371749 NCBI chrNW_004955451:16,058,916...16,091,831
Ensembl chrNW_004955451:16,058,727...16,092,589
JBrowse link
G Acss1 acyl-CoA synthetase short chain family member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:16788062)
(PMID:11150295)
UniProt
MGI
PMID:11150295 PMID:16788062 NCBI chrNW_004955415:31,117,542...31,154,654
Ensembl chrNW_004955415:31,117,303...31,154,654
JBrowse link
G Acss2 acyl-CoA synthetase short chain family member 2 acts_upstream_of_or_within ISO (PMID:11150295) MGI PMID:11150295 NCBI chrNW_004955422:26,450,899...26,500,336
Ensembl chrNW_004955422:26,451,598...26,500,546
JBrowse link
G Dip2a disco interacting protein 2 homolog A involved_in ISO (PMID:30672040) UniProt PMID:30672040 NCBI chrNW_004955407:42,857,297...42,961,831
Ensembl chrNW_004955407:42,857,344...42,959,265
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO (PMID:29754768) UniProt PMID:29754768 NCBI chrNW_004955537:2,080,865...2,084,199
Ensembl chrNW_004955537:2,080,865...2,085,003
JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlat dihydrolipoamide S-acetyltransferase involved_in ISO (PMID:17314311)
(PMID:27621431)
(PMID:24534072)
RGD
MGI
ComplexPortal
PMID:7487891 PMID:17314311 PMID:24534072 PMID:27621431 RGD:1599112 NCBI chrNW_004955412:13,718,091...13,746,220
Ensembl chrNW_004955412:13,718,067...13,744,239
JBrowse link
G Dld dihydrolipoamide dehydrogenase involved_in ISO (PMID:27621431)
(PMID:17314311)
(PMID:24534072)
RGD
MGI
ComplexPortal
PMID:7487891 PMID:17314311 PMID:24534072 PMID:27621431 RGD:1599112 NCBI chrNW_004955410:12,212,981...12,238,561
Ensembl chrNW_004955410:12,212,963...12,238,561
JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 involved_in
acts_upstream_of_or_within
ISO (PMID:22628558) MGI PMID:22628558 NCBI chrNW_004955439:15,515,966...15,531,618
Ensembl chrNW_004955439:15,516,090...15,531,116
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within
involved_in
ISO (PMID:22628558)
(PMID:24910426)
MGI PMID:22628558 PMID:24910426 NCBI chrNW_004955462:9,177,484...9,193,646 JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 involved_in
acts_upstream_of_or_within
ISO (PMID:19081061), (PMID:24534072)
(PMID:18586888)
RGD
ComplexPortal
MGI
PMID:7487891 PMID:18586888 PMID:19081061 PMID:24534072 RGD:1599112 NCBI chrNW_004955586:98,492...114,927
Ensembl chrNW_004955586:97,172...114,928
JBrowse link
G Pdha2 pyruvate dehydrogenase E1 subunit alpha 2 ISO RGD PMID:7487891 RGD:1599112 NCBI chrNW_004955405:6,383,088...6,383,946 JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta involved_in ISO (PMID:19081061), (PMID:24534072) RGD
UniProt
PMID:7487891 PMID:19081061 PMID:24534072 RGD:1599112 NCBI chrNW_004955430:1,707,615...1,713,541
Ensembl chrNW_004955430:1,707,615...1,713,541
JBrowse link
G Pdhx pyruvate dehydrogenase complex component X involved_in ISO (PMID:24534072)
(PMID:17314311)
(PMID:27621431)
ComplexPortal
MGI
PMID:17314311 PMID:24534072 PMID:27621431 NCBI chrNW_004955422:11,335,766...11,405,565
Ensembl chrNW_004955422:11,335,766...11,405,565
JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcdh glutaryl-CoA dehydrogenase ISO RGD PMID:6895440 RGD:1598697 NCBI chrNW_004955415:31,952,400...31,958,067
Ensembl chrNW_004955415:31,952,580...31,961,615
JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004955403:24,190,674...24,235,354
Ensembl chrNW_004955403:24,190,674...24,236,780
JBrowse link
G Acsl4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004955490:6,143,833...6,228,395
Ensembl chrNW_004955490:6,143,833...6,228,452
JBrowse link
G Acsl5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004955431:17,477,113...17,524,539
Ensembl chrNW_004955431:17,477,086...17,524,539
JBrowse link
G Acsl6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chrNW_004955408:3,336,214...3,391,117
Ensembl chrNW_004955408:3,333,392...3,392,141
JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (PMID:18487439) UniProt PMID:18487439 NCBI chrNW_004955455:10,282,308...10,427,439
Ensembl chrNW_004955455:10,308,192...10,426,076
JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgk1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) UniProt PMID:26942675 NCBI chrNW_004955557:1,566,534...1,584,799 JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) BHF-UCL PMID:17371050 NCBI chrNW_004955412:10,350,088...10,369,806
Ensembl chrNW_004955412:10,349,593...10,369,806
JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in ISO (PMID:22195962) UniProt PMID:22195962 NCBI chrNW_004955449:2,546,790...2,582,402
Ensembl chrNW_004955449:2,549,139...2,582,243
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO (PMID:22360721) UniProt PMID:22360721 NCBI chrNW_004955451:11,547,660...11,559,266
Ensembl chrNW_004955451:11,547,660...11,559,403
JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) UniProt PMID:22865452 NCBI chrNW_004955509:4,809,422...4,888,802
Ensembl chrNW_004955509:4,809,399...4,878,976
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO (PMID:21852536)
(PMID:16606348)
UniProt PMID:16606348 PMID:21852536 NCBI chrNW_004955432:12,169,548...12,182,064
Ensembl chrNW_004955432:12,169,435...12,182,409
JBrowse link
G Tpk1 thiamin pyrophosphokinase 1 involved_in ISO (PMID:38547260) UniProt PMID:38547260 NCBI chrNW_004955491:621,941...968,570
Ensembl chrNW_004955491:623,530...968,253
JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snca synuclein alpha acts_upstream_of_or_within ISO (PMID:16636270)
(PMID:16734431)
MGI PMID:16636270 PMID:16734431 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403
JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmut methylmalonyl-CoA mutase involved_in ISO (PMID:7904153) MGI PMID:7904153 NCBI chrNW_004955411:8,363,142...8,397,839
Ensembl chrNW_004955411:8,363,142...8,399,216
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    cellular process 12010
      metabolic process 7974
        sulfur compound metabolic process 248
          thioester metabolic process 69
            thioester biosynthetic process 28
              acyl-CoA biosynthetic process + 28
paths to the root