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ONTOLOGY REPORT - ANNOTATIONS

Term:thioester biosynthetic process
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Accession:GO:0035384 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
Synonyms:exact_synonym: thioester anabolism;   thioester biosynthesis;   thioester formation;   thioester synthesis


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acetyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787 		JBrowse link
G ACLY ATP citrate lyase involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:15,385,335...15,447,269
Ensembl chr17:15,615,994...15,664,800 		JBrowse link
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11150295) Ensembl
TreeGrafter
MGI		 PMID:11150295 GO_REF:0000107 GO_REF:0000118 NCBI chr20:24,946,629...25,001,311
Ensembl chr20:25,293,511...25,349,017 		JBrowse link
G ACSS2 acyl-CoA synthetase short chain family member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11150295) MGI
TreeGrafter		 PMID:11150295 GO_REF:0000118 NCBI chr20:31,205,104...31,256,263
Ensembl chr20:32,329,721...32,380,526 		JBrowse link
G DIP2A disco interacting protein 2 homolog A involved_in ISO (PMID:30672040) UniProt PMID:30672040 NCBI chr21:32,921,019...33,034,988
Ensembl chr21:46,060,713...46,168,885 		JBrowse link
G MLYCD malonyl-CoA decarboxylase involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:17316539 GO_REF:0000107 GO_REF:0000118 RGD:1600790 NCBI chr16:64,520,860...64,537,955
Ensembl chr16:83,912,793...83,929,162 		JBrowse link
G PPCS phosphopantothenoylcysteine synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:41,756,403...41,773,430
Ensembl chr 1:43,136,720...43,140,620 		JBrowse link
acetyl-CoA biosynthetic process from acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSS1 acyl-CoA synthetase short chain family member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr20:24,946,629...25,001,311
Ensembl chr20:25,293,511...25,349,017 		JBrowse link
acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLAT dihydrolipoamide S-acetyltransferase involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:7487891 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1599112 NCBI chr11:106,910,857...106,950,851
Ensembl chr11:110,756,001...110,792,795 		JBrowse link
G DLD dihydrolipoamide dehydrogenase involved_in ISO
IEA		 RGD
Ensembl		 PMID:7487891 GO_REF:0000107 RGD:1599112 NCBI chr 7:99,872,020...99,901,884
Ensembl chr 7:112,593,934...112,623,629 		JBrowse link
G MPC1 mitochondrial pyruvate carrier 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:22628558) MGI PMID:22628558 NCBI chr 6:164,331,604...164,349,747 JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910426)
(PMID:22628558)		 Ensembl
MGI		 PMID:22628558 PMID:24910426 GO_REF:0000107 NCBI chr 1:143,406,611...143,424,508
Ensembl chr 1:147,132,213...147,151,648 		JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18586888) RGD
TreeGrafter
MGI
Ensembl
InterPro		 PMID:7487891 PMID:18586888 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1599112 NCBI chr  X:11,967,944...11,985,837
Ensembl chr  X:19,330,508...19,348,443 		JBrowse link
G PDHA2 pyruvate dehydrogenase E1 subunit alpha 2 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:7487891 GO_REF:0000118 RGD:1599112 NCBI chr 4:88,213,492...88,216,451
Ensembl chr 4:98,883,109...98,884,853 		JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:7487891 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1599112 NCBI chr 3:58,359,753...58,366,094
Ensembl chr 3:59,776,618...59,782,411 		JBrowse link
G PDHX pyruvate dehydrogenase complex component X involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr11:34,889,242...34,968,886
Ensembl chr11:34,764,450...34,844,166 		JBrowse link
fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCDH glutaryl-CoA dehydrogenase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:6895440 GO_REF:0000118 RGD:1598697 NCBI chr19:12,452,779...12,461,757
Ensembl chr19:13,195,241...13,204,223 		JBrowse link
long-chain fatty-acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 4:176,920,811...176,991,495
Ensembl chr 4:189,145,403...189,198,646 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:98,731,109...98,841,067
Ensembl chr  X:109,206,964...109,310,914 		JBrowse link
G ACSL5 acyl-CoA synthetase long chain family member 5 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:16466685 GO_REF:0000118 RGD:2312800 NCBI chr10:108,965,559...109,019,240
Ensembl chr10:112,407,161...112,457,892 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 5:127,373,306...127,434,954
Ensembl chr 5:133,537,292...133,586,711 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 1:42,664,818...42,686,475
Ensembl chr 1:44,044,693...44,048,769 		JBrowse link
G ELOVL3 ELOVL fatty acid elongase 3 involved_in IEA UniProt GO_REF:0000104 NCBI chr10:98,788,505...98,833,146
Ensembl chr10:102,297,291...102,300,594 		JBrowse link
G ELOVL4 ELOVL fatty acid elongase 4 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:77,798,058...77,830,840
Ensembl chr 6:81,068,882...81,102,050 		JBrowse link
G ELOVL5 ELOVL fatty acid elongase 5 involved_in IEA UniProt GO_REF:0000104 NCBI chr 6:52,822,038...52,902,122
Ensembl chr 6:54,451,887...54,485,878 		JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 involved_in IEA UniProt GO_REF:0000104 NCBI chr 4:102,545,815...102,695,536
Ensembl chr 4:113,110,466...113,260,444 		JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA UniProt GO_REF:0000104 NCBI chr 5:53,156,518...53,248,839
Ensembl chr 5:54,853,330...54,888,930 		JBrowse link
malonyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha involved_in IEA UniProt GO_REF:0000041 NCBI chr17:19,670,114...19,998,903
Ensembl chr17:19,969,205...20,297,651 		JBrowse link
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl
UniProt		 GO_REF:0000041 GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847 		JBrowse link
negative regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:26942675) UniProt PMID:26942675 NCBI chr  X:67,280,269...67,302,307
Ensembl chr  X:77,391,805...77,414,459 		JBrowse link
propionyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT1 acetyl-CoA acetyltransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,008,564...103,034,697
Ensembl chr11:106,483,563...106,509,787 		JBrowse link
regulation of acetyl-CoA biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDK1 pyruvate dehydrogenase kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:59,841,840...59,958,504
Ensembl chr2B:177,297,840...177,341,113 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,185,463...44,202,221
Ensembl chr17:49,060,030...49,076,115 		JBrowse link
G PDK3 pyruvate dehydrogenase kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:17,062,278...17,147,489
Ensembl chr  X:24,430,028...24,504,730 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:87,540,600...87,553,673
Ensembl chr 7:101,128,060...101,141,157 		JBrowse link
G TPK1 thiamin pyrophosphokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:136,165,941...136,549,606
Ensembl chr 7:148,654,445...149,036,342 		JBrowse link
regulation of acyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNCA synuclein alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16734431)
(PMID:16636270)		 MGI
Ensembl		 PMID:16636270 PMID:16734431 GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
succinyl-CoA biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMUT methylmalonyl-CoA mutase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,007,500...49,040,470
Ensembl chr 6:50,269,644...50,302,593 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16643
    cellular process 16206
      metabolic process 10770
        sulfur compound metabolic process 326
          thioester metabolic process 88
            thioester biosynthetic process 36
              acyl-CoA biosynthetic process + 36
paths to the root