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ONTOLOGY REPORT - ANNOTATIONS

Term:endocrine system development
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Accession:GO:0035270 term browser browse the term
Definition:Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.


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endocrine system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3655758|PMID:16951258) MGI
Ensembl		 PMID:16951258 GO_REF:0000107 MGI:3655758 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:3576468|PMID:9140068) BHF-UCL
BHF-UCL
Ensembl
MGI		 PMID:9140068 GO_REF:0000024 GO_REF:0000107 MGI:3576468 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G GHRH growth hormone releasing hormone involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:3607618|PMID:15985453) BHF-UCL
Ensembl
BHF-UCL
MGI		 PMID:15985453 GO_REF:0000024 GO_REF:0000107 MGI:3607618 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,086...37,261,819 		JBrowse link
G GHRHR growth hormone releasing hormone receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:51713|PMID:1504465), (MGI:54124|PMID:1270792), (MGI:63703|PMID:1329576) MGI
Ensembl		 PMID:1270792 PMID:1329576 PMID:1504465 GO_REF:0000107 MGI:51713 MGI:54124 MGI:63703 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254 		JBrowse link
G GSX1 GS homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:79250|PMID:8631293) Ensembl
Ensembl
MGI		 PMID:8631293 GO_REF:0000107 MGI:79250 NCBI chr13:27,792,483...27,794,768
Ensembl chr13:27,792,483...27,794,768 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3827091|PMID:18996108) Ensembl
Ensembl
MGI		 PMID:18996108 GO_REF:0000107 MGI:3827091 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G POU1F1 POU class 1 homeobox 1 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:16216912 GO_REF:0000107 RGD:1601440 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
G PROP1 PROP paired-like homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3827091|PMID:18996108) MGI
Ensembl		 PMID:18996108 GO_REF:0000107 MGI:3827091 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:894559|PMID:9247269) Ensembl
Ensembl
MGI		 PMID:9247269 GO_REF:0000107 MGI:894559 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3689142|PMID:16932809) Ensembl
Ensembl
MGI
RGD		 PMID:16932809 PMID:21815952 GO_REF:0000107 MGI:3689142 RGD:8661681 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOX2 dual oxidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3712355|PMID:17440044) Ensembl
Ensembl
MGI		 PMID:17440044 GO_REF:0000107 MGI:3712355 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
adrenal chromaffin cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2387977|PMID:12361965) Ensembl
Ensembl
MGI		 PMID:12361965 GO_REF:0000107 MGI:2387977 NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
adrenal cortex development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC5 armadillo repeat containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5913685|PMID:28911199) Ensembl
Ensembl
MGI		 PMID:28911199 GO_REF:0000107 MGI:5913685 NCBI chr16:31,458,304...31,467,167
Ensembl chr16:31,458,080...31,467,166 		JBrowse link
adrenal cortex formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G WT1 WT1 transcription factor involved_in ISS UniProt
UniProt		 GO_REF:0000024 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564 		JBrowse link
adrenal gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2A activin A receptor type 2A ISO RGD PMID:12844345 RGD:728125 NCBI chr 2:147,844,517...147,930,822
Ensembl chr 2:147,844,517...147,930,826 		JBrowse link
G ACVR2B activin A receptor type 2B ISO RGD PMID:12844345 RGD:728125 NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142 		JBrowse link
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2180727|PMID:8647961) Ensembl
Ensembl
MGI		 PMID:8647961 GO_REF:0000107 MGI:2180727 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G ARID5B AT-rich interaction domain 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2137956|PMID:11483573) Ensembl
Ensembl
MGI		 PMID:11483573 GO_REF:0000107 MGI:2137956 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3839493|PMID:19276117) Ensembl
MGI		 PMID:19276117 GO_REF:0000107 MGI:3839493 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2179743|PMID:11694877), (MGI:3606737|PMID:15615595) MGI
Ensembl		 PMID:11694877 PMID:15615595 GO_REF:0000107 MGI:2179743 MGI:3606737 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G CRH corticotropin releasing hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1860037|PMID:10861000) MGI
Ensembl
Ensembl		 PMID:10861000 GO_REF:0000107 MGI:1860037 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 ISO RGD PMID:7829497 RGD:1299585 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO RGD PMID:17065412 RGD:4889133 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:8097866 RGD:4145970 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 involved_in ISO
IEA		 RGD
Ensembl
Ensembl		 PMID:10098502 GO_REF:0000107 RGD:7829725 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEP (PMID:12844346) UniProt
UniProt		 PMID:12844346 NCBI chr11:11,963,036...12,009,745
Ensembl chr11:11,956,207...12,009,769 		JBrowse link
G FDX1 ferredoxin 1 ISO RGD PMID:8097866 RGD:4145970 NCBI chr11:110,429,331...110,464,884
Ensembl chr11:110,429,948...110,464,884 		JBrowse link
G FSTL3 follistatin like 3 ISO RGD PMID:14692692 RGD:1302294 NCBI chr19:676,392...683,385
Ensembl chr19:676,392...683,392 		JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:69334|PMID:7958830) MGI PMID:7958830 MGI:69334 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:1935797 RGD:4889583 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO (MGI:5493430|PMID:23300479) CACAO PMID:23300479 MGI:5493430 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G INSR insulin receptor involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414 		JBrowse link
G LINC02210-CRHR1 LINC02210-CRHR1 readthrough involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:45,620,346...45,835,828
Ensembl chr17:45,784,280...45,835,828
Ensembl chr17:45,784,280...45,835,828 		JBrowse link
G LY6E lymphocyte antigen 6 family member E acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2157257|PMID:11784869) MGI
Ensembl		 PMID:11784869 GO_REF:0000107 MGI:2157257 NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832 		JBrowse link
G MDK midkine involved_in ISS
IEA		 UniProt
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837 		JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:3689139|PMID:16906226) HGNC-UCL
Ensembl
HGNC-UCL
MGI		 PMID:16906226 GO_REF:0000024 GO_REF:0000107 MGI:3689139 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 involved_in
acts_upstream_of_or_within		 IMP
IBA
IEA
ISO		 (PMID:7990953)
(PMID:21873635)
(MGI:2159510|PMID:11796523)		 HGNC-UCL
GO_Central
HGNC-UCL
Ensembl
MGI
GO_Central		 PMID:7990953 PMID:11796523 PMID:21873635 GO_REF:0000107 MGI:2159510 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:74913|PMID:7628695) MGI
Ensembl		 PMID:7628695 GO_REF:0000107 MGI:74913 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3604914|PMID:16176945)
(MGI:2159510|PMID:11796523)
(MGI:5287526|PMID:21820362)		 Ensembl
Ensembl
MGI		 PMID:11796523 PMID:16176945 PMID:21820362 GO_REF:0000107 MGI:2159510 MGI:3604914 MGI:5287526 NCBI chr 9:124,481,236...124,507,399
Ensembl chr 9:124,481,236...124,507,420 		JBrowse link
G PBX1 PBX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2683990|PMID:14595835) Ensembl
Ensembl
MGI		 PMID:14595835 GO_REF:0000107 MGI:2683990 NCBI chr 1:164,559,184...164,886,047
Ensembl chr 1:164,555,584...164,899,296 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3820330|PMID:19056881) Ensembl
Ensembl
MGI		 PMID:19056881 GO_REF:0000107 MGI:3820330 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta acts_upstream_of_or_within ISO (MGI:3820330|PMID:19056881) MGI PMID:19056881 MGI:3820330 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:16140489 RGD:5130728 NCBI chr17:39,668,019...39,670,475
Ensembl chr17:39,667,981...39,670,475 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEP (PMID:12065233) UniProt
UniProt		 PMID:12065233 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:12844345 GO_REF:0000107 RGD:728125 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:12844345 GO_REF:0000107 RGD:728125 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SMAD4 SMAD family member 4 involved_in ISO
IEA		 RGD
Ensembl
Ensembl		 PMID:12844345 GO_REF:0000107 RGD:728125 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 involved_in IMP (PMID:17273977) DFLAT
DFLAT		 PMID:17273977 NCBI chr15:74,179,466...74,212,259
Ensembl chr15:74,179,466...74,212,267 		JBrowse link
G THRA thyroid hormone receptor alpha ISO RGD PMID:17496154 RGD:2314319 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867 		JBrowse link
G TSPO translocator protein involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:9927316 GO_REF:0000107 RGD:2317174 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
G WNT11 Wnt family member 11 involved_in IEP (PMID:9757009) UniProt
UniProt		 PMID:9757009 NCBI chr11:76,186,325...76,210,761
Ensembl chr11:76,186,325...76,210,736 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEP (PMID:12844346) UniProt
UniProt		 PMID:12844346 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
G WT1 WT1 transcription factor involved_in IGI (PMID:10101119) UniProt
UniProt		 PMID:10101119 NCBI chr11:32,387,775...32,435,539
Ensembl chr11:32,387,775...32,435,564 		JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:1202291|PMID:9463347) UniProt
UniProt
Ensembl
MGI		 PMID:9463347 GO_REF:0000024 GO_REF:0000107 MGI:1202291 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202291|PMID:9463347) MGI
Ensembl
Ensembl		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,708...122,898,236 		JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1202291|PMID:9463347) Ensembl
Ensembl
MGI		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr10:101,770,109...101,780,369
Ensembl chr10:101,770,109...101,780,371 		JBrowse link
endocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IBA
ISO		 (PMID:21873635) GO_Central
GO_Central
RGD		 PMID:7527053 PMID:21873635 RGD:2306957 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:11000281 GO_REF:0000107 RGD:2315710 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293 		JBrowse link
G CLU clusterin ISO RGD PMID:16411126 RGD:1582421 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in IMP (PMID:12086964) UniProt
UniProt		 PMID:12086964 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G FOXA2 forkhead box A2 involved_in
acts_upstream_of_or_within		 IDA
ISO		 (PMID:12124776)
(MGI:3530180|PMID:15680365)		 BHF-UCL
BHF-UCL
MGI		 PMID:12124776 PMID:15680365 MGI:3530180 NCBI chr20:22,580,998...22,585,490
Ensembl chr20:22,580,998...22,585,455 		JBrowse link
G GIP gastric inhibitory polypeptide involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4940930|PMID:21270265) Ensembl
Ensembl
MGI		 PMID:21270265 GO_REF:0000107 MGI:4940930 NCBI chr17:48,958,554...48,968,596
Ensembl chr17:48,958,554...48,968,596 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4940930|PMID:21270265) Ensembl
Ensembl
MGI		 PMID:21270265 GO_REF:0000107 MGI:4940930 NCBI chr19:45,668,221...45,683,722
Ensembl chr19:45,668,221...45,683,722 		JBrowse link
G HNF1A HNF1 homeobox A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HNF1B HNF1 homeobox B involved_in IMP (PMID:16801329) UniProt
UniProt		 PMID:16801329 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059 		JBrowse link
G IL6 interleukin 6 involved_in ISS BHF-UCL
BHF-UCL		 GO_REF:0000024 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor involved_in IMP
IC		 (PMID:18719127) BHF-UCL
BHF-UCL		 PMID:18719127 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3619850|PMID:16511571) MGI
Ensembl		 PMID:16511571 GO_REF:0000107 MGI:3619850 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:21873635)
(MGI:1344214|PMID:10471501)		 GO_Central
GO_Central
MGI		 PMID:10471501 PMID:21873635 MGI:1344214 NCBI chr 7:157,004,854...157,010,663
Ensembl chr 7:156,994,051...157,010,663 		JBrowse link
G MYT1 myelin transcription factor 1 acts_upstream_of_or_within ISO (MGI:3763794|PMID:17928203) MGI PMID:17928203 MGI:3763794 NCBI chr20:64,164,452...64,242,253
Ensembl chr20:64,102,394...64,242,253 		JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in ISS
IEA		 (PMID:9308961) BHF-UCL
Ensembl
BHF-UCL		 PMID:9308961 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827 		JBrowse link
G NEUROG3 neurogenin 3 involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr10:69,571,485...69,573,422
Ensembl chr10:69,571,698...69,573,422 		JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1270972|PMID:9584121) MGI
Ensembl		 PMID:9584121 GO_REF:0000107 MGI:1270972 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3579924|PMID:15944193) MGI
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G NKX6-2 NK6 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3579924|PMID:15944193) Ensembl
Ensembl
MGI		 PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr10:132,783,181...132,786,147
Ensembl chr10:132,783,179...132,786,147 		JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3710726|PMID:17400205) Ensembl
Ensembl
MGI		 PMID:17400205 GO_REF:0000107 MGI:3710726 NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078 		JBrowse link
G ONECUT2 one cut homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3710726|PMID:17400205) Ensembl
Ensembl
MGI		 PMID:17400205 GO_REF:0000107 MGI:3710726 NCBI chr18:57,435,374...57,491,298
Ensembl chr18:57,435,374...57,491,298 		JBrowse link
G PDE3B phosphodiesterase 3B acts_upstream_of_or_within ISO (MGI:3040550|PMID:14736883) MGI PMID:14736883 MGI:3040550 NCBI chr11:14,643,804...14,872,044
Ensembl chr11:14,643,804...14,872,044 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3771560|PMID:18155690) MGI
Ensembl		 PMID:18155690 GO_REF:0000107 MGI:3771560 NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313 		JBrowse link
G RFX3 regulatory factor X3 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:3,218,297...3,526,001
Ensembl chr 9:3,218,297...3,526,004 		JBrowse link
G RFX6 regulatory factor X6 involved_in IMP (PMID:20148032) UniProt
UniProt		 PMID:20148032 NCBI chr 6:116,877,242...116,932,161
Ensembl chr 6:116,877,212...116,932,161 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3611650|PMID:16306355) Ensembl
Ensembl
MGI		 PMID:16306355 GO_REF:0000107 MGI:3611650 NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3815251|PMID:18723011) Ensembl
Ensembl
MGI		 PMID:18723011 GO_REF:0000107 MGI:3815251 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416 		JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PROP1 PROP paired-like homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3690195|PMID:16678101) MGI
Ensembl
Ensembl		 PMID:16678101 GO_REF:0000107 MGI:3690195 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3043884|PMID:15037319) Ensembl
Ensembl
MGI		 PMID:15037319 GO_REF:0000107 MGI:3043884 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1351379|PMID:10615124) Ensembl
MGI
Ensembl		 PMID:10615124 GO_REF:0000107 MGI:1351379 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G MIR7-1 microRNA 7-1 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) MGI PMID:22764048 MGI:5437569 NCBI chr 9:83,969,748...83,969,857
Ensembl chr 9:83,969,748...83,969,857 		JBrowse link
negative regulation of thyroid gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR1-2 microRNA 1-2 ISO RGD PMID:21816899 RGD:10059418 NCBI chr18:21,829,004...21,829,088
Ensembl chr18:21,829,004...21,829,088 		JBrowse link
G MIR28 microRNA 28 ISO RGD PMID:21816899 RGD:10059418 NCBI chr 3:188,688,781...188,688,866
Ensembl chr 3:188,688,781...188,688,866 		JBrowse link
G MIR296 microRNA 296 ISO RGD PMID:21816899 RGD:10059418 NCBI chr20:58,817,615...58,817,694
Ensembl chr20:58,817,615...58,817,694 		JBrowse link
G MIR371A microRNA 371a ISO RGD PMID:21816899 RGD:10059418 NCBI chr19:53,787,675...53,787,741
Ensembl chr19:53,787,675...53,787,741 		JBrowse link
G RAP1GAP RAP1 GTPase activating protein involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:17646383 GO_REF:0000107 RGD:9835038 NCBI chr 1:21,596,221...21,669,357
Ensembl chr 1:21,596,221...21,669,357 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in TAS (PMID:19366350) UniProt
UniProt		 PMID:19366350 NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in TAS (PMID:19366350) UniProt
UniProt		 PMID:19366350 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTP orthopedia homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1347696|PMID:10557207) Ensembl
Ensembl
MGI		 PMID:10557207 GO_REF:0000107 MGI:1347696 NCBI chr 5:77,628,712...77,638,713
Ensembl chr 5:77,628,712...77,638,713 		JBrowse link
G POU3F2 POU class 3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:77941|PMID:8543156) Ensembl
Ensembl
MGI		 PMID:8543156 GO_REF:0000107 MGI:77941 NCBI chr 6:98,834,574...98,839,458
Ensembl chr 6:98,834,574...98,839,458 		JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in IMP
IEA		 (PMID:20592023) BHF-UCL
BHF-UCL
Ensembl		 PMID:20592023 GO_REF:0000107 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3701716|PMID:16887115) Ensembl
Ensembl
MGI		 PMID:16887115 GO_REF:0000107 MGI:3701716 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:1351379|PMID:10615124) MGI
Ensembl		 PMID:10615124 GO_REF:0000107 MGI:1351379 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (MGI:3619850|PMID:16511571) UniProt
MGI
UniProt
Ensembl		 PMID:16511571 GO_REF:0000024 GO_REF:0000107 MGI:3619850 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3579924|PMID:15944193) MGI
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G NKX6-2 NK6 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3579924|PMID:15944193) MGI
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr10:132,783,181...132,786,147
Ensembl chr10:132,783,179...132,786,147 		JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859126|PMID:10825208) MGI
Ensembl		 PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:20592023 RGD:8552352 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G RFX6 regulatory factor X6 involved_in ISS
IEA		 UniProt
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:116,877,242...116,932,161
Ensembl chr 6:116,877,212...116,932,161 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO (MGI:5618205|PMID:25186293) MGI PMID:25186293 MGI:5618205 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,667 		JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3768695|PMID:17988662) Ensembl
Ensembl
MGI		 PMID:17988662 GO_REF:0000107 MGI:3768695 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3768695|PMID:17988662)
(MGI:3703458|PMID:17202186)		 Ensembl
Ensembl
MGI		 PMID:17202186 PMID:17988662 GO_REF:0000107 MGI:3703458 MGI:3768695 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859126|PMID:10825208) MGI
Ensembl		 PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078 		JBrowse link
G RFX6 regulatory factor X6 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:116,877,242...116,932,161
Ensembl chr 6:116,877,212...116,932,161 		JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RFX6 regulatory factor X6 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:116,877,242...116,932,161
Ensembl chr 6:116,877,212...116,932,161 		JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3768695|PMID:17988662) Ensembl
Ensembl
MGI		 PMID:17988662 GO_REF:0000107 MGI:3768695 NCBI chr 2:181,668,295...181,680,517
Ensembl chr 2:181,668,295...181,680,827 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3768695|PMID:17988662) Ensembl
Ensembl
MGI		 PMID:17988662 GO_REF:0000107 MGI:3768695 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
parathyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3614586|PMID:16399080) Ensembl
Ensembl
MGI		 PMID:16399080 GO_REF:0000107 MGI:3614586 NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4460059|PMID:20484821) Ensembl
Ensembl
MGI		 PMID:20484821 GO_REF:0000107 MGI:4460059 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G GCM2 glial cells missing transcription factor 2 involved_in
acts_upstream_of_or_within		 IMP
ISO		 (PMID:15728199), (PMID:27745835)
(MGI:5780847|PMID:19968565)		 UniProt
UniProt
MGI		 PMID:15728199 PMID:19968565 PMID:27745835 MGI:5780847 NCBI chr 6:10,873,223...10,882,041
Ensembl chr 6:10,873,223...10,882,041 		JBrowse link
G HOXA3 homeobox A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2149273|PMID:11476574) Ensembl
Ensembl
MGI		 PMID:11476574 GO_REF:0000107 MGI:2149273 NCBI chr 7:27,107,010...27,152,583
Ensembl chr 7:27,106,184...27,152,583 		JBrowse link
G PAX1 paired box 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2149273|PMID:11476574) Ensembl
Ensembl
MGI		 PMID:11476574 GO_REF:0000107 MGI:2149273 NCBI chr20:21,705,664...21,718,481
Ensembl chr20:21,705,659...21,718,481 		JBrowse link
G TBX1 T-box transcription factor 1 involved_in IMP (PMID:14585638) UniProt
UniProt		 PMID:14585638 NCBI chr22:19,756,703...19,783,593
Ensembl chr22:19,756,703...19,783,593 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (MGI:3703113|PMID:17078885) BHF-UCL
MGI
Ensembl
BHF-UCL		 PMID:17078885 GO_REF:0000024 GO_REF:0000107 MGI:3703113 NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:18160680 RGD:2325274 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:17180597 GO_REF:0000107 RGD:2306413 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866 		JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 ISO RGD PMID:17180597 RGD:2306413 NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,877,714...100,916,626 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1306869|PMID:9806931) Ensembl
Ensembl
MGI		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3709795|PMID:17359964) Ensembl
Ensembl
MGI		 PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr10:86,755,763...86,927,969
Ensembl chr10:86,756,601...86,932,825 		JBrowse link
G CDH1 cadherin 1 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:17373711 GO_REF:0000107 RGD:2289637 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3611103|PMID:16141355) Ensembl
MGI
Ensembl		 PMID:16141355 GO_REF:0000107 MGI:3611103 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO RGD PMID:8946059 RGD:2313681 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3688470|PMID:11062007) Ensembl
Ensembl
MGI		 PMID:11062007 GO_REF:0000107 MGI:3688470 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3625416|PMID:16543408) Ensembl
MGI
Ensembl		 PMID:16543408 GO_REF:0000107 MGI:3625416 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G GLI1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1354188|PMID:10725236) InterPro
Ensembl
InterPro
MGI
Ensembl		 PMID:10725236 GO_REF:0000002 GO_REF:0000107 MGI:1354188 NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268 		JBrowse link
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:1354188|PMID:10725236) UniProt
UniProt
Ensembl
Ensembl
MGI		 PMID:10725236 GO_REF:0000024 GO_REF:0000107 MGI:1354188 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653 		JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3712393|PMID:17426285)
(MGI:3664138|PMID:17015435), (MGI:3712393|PMID:17426285)		 MGI
Ensembl		 PMID:17015435 PMID:17426285 GO_REF:0000107 MGI:3664138 MGI:3712393 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IMP
IEA		 (PMID:21873635)
(MGI:3821905|PMID:19093031)
(PMID:26781211)
(MGI:4440397|PMID:20181723)
(MGI:1206234|PMID:9620767), (MGI:2154557|PMID:11731482)
(MGI:3821506|PMID:18775421)		 GO_Central
MGI
UniProt
GO_Central
Ensembl
UniProt		 PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 More... GO_REF:0000107 MGI:1206234 MGI:2154557 MGI:3821506 MGI:3821905 MGI:4440397 NCBI chr 3:57,197,838...57,227,615
Ensembl chr 3:57,197,838...57,227,606 		JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:54708|PMID:504232) MGI PMID:504232 MGI:54708 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G INHBB inhibin subunit beta B involved_in ISO
IEA		 RGD
Ensembl
Ensembl		 PMID:18160680 GO_REF:0000107 RGD:2325274 NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1306869|PMID:9806931) Ensembl
Ensembl
MGI		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730 		JBrowse link
G KDM1A lysine demethylase 1A acts_upstream_of_or_within ISO (MGI:3710033|PMID:17392792) MGI PMID:17392792 MGI:3710033 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689 		JBrowse link
G LHX3 LIM homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3771226|PMID:18037398) Ensembl
Ensembl
MGI		 PMID:18037398 GO_REF:0000107 MGI:3771226 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G MSX1 msh homeobox 1 ISO RGD PMID:16451220 RGD:5132608 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936 		JBrowse link
G NKX2-1 NK2 homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1306869|PMID:9806931) MGI
Ensembl		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3709795|PMID:17359964) Ensembl
Ensembl
MGI		 PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 involved_in NAS (PMID:15464421) UniProt
UniProt		 PMID:15464421 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1350715|PMID:10588713) Ensembl
Ensembl
MGI		 PMID:10588713 GO_REF:0000107 MGI:1350715 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 involved_in ISO
IEA		 RGD
Ensembl
Ensembl		 PMID:15208361 GO_REF:0000107 RGD:2308902 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
G PITX1 paired like homeodomain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1332284|PMID:10049363) Ensembl
Ensembl
MGI		 PMID:10049363 GO_REF:0000107 MGI:1332284 NCBI chr 5:135,027,734...135,034,789
Ensembl chr 5:135,027,734...135,034,813 		JBrowse link
G PITX2 paired like homeodomain 2 acts_upstream_of_or_within ISO (MGI:1344731|PMID:10498698)
(MGI:1345532|PMID:10499586)		 MGI PMID:10498698 PMID:10499586 MGI:1344731 MGI:1345532 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:3625414|PMID:16556738) MGI PMID:16556738 MGI:3625414 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2154557|PMID:11731482) InterPro
Ensembl
InterPro
MGI		 PMID:11731482 GO_REF:0000002 GO_REF:0000107 MGI:2154557 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3664138|PMID:17015435) Ensembl
Ensembl
MGI		 PMID:17015435 GO_REF:0000107 MGI:3664138 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEP (PMID:12065233) UniProt
UniProt		 PMID:12065233 NCBI chr16:51,135,982...51,152,334
Ensembl chr16:51,135,982...51,152,334 		JBrowse link
G SIX3 SIX homeobox 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (MGI:3821506|PMID:18775421) UniProt
UniProt
MGI		 PMID:18775421 GO_REF:0000024 MGI:3821506 NCBI chr 2:44,941,702...44,946,071
Ensembl chr 2:44,941,702...44,946,071 		JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in IEP (PMID:18285410) UniProt
UniProt		 PMID:18285410 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G SOX3 SRY-box transcription factor 3 involved_in ISS UniProt
UniProt		 GO_REF:0000024 NCBI chr  X:140,502,985...140,505,069
Ensembl chr  X:140,502,985...140,505,069 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:8770891 GO_REF:0000107 RGD:4892048 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,427...6,674,386 		JBrowse link
G TBX19 T-box transcription factor 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2137424|PMID:11447259) Ensembl
Ensembl
MGI		 PMID:11447259 GO_REF:0000107 MGI:2137424 NCBI chr 1:168,280,877...168,314,426
Ensembl chr 1:168,280,877...168,314,426 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:3763872|PMID:17919533) MGI PMID:17919533 MGI:3763872 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in ISS
IEA		 UniProt
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in ISS BHF-UCL
BHF-UCL		 GO_REF:0000024 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G RFX3 regulatory factor X3 involved_in ISS
IEA		 (PMID:20413507) BHF-UCL
BHF-UCL
Ensembl		 PMID:20413507 GO_REF:0000107 NCBI chr 9:3,218,297...3,526,001
Ensembl chr 9:3,218,297...3,526,004 		JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:80537|PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G PITX2 paired like homeodomain 2 involved_in TAS (PMID:10372733) BHF-UCL
BHF-UCL		 PMID:10372733 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-211163 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in ISS UniProt
UniProt		 GO_REF:0000024 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266 		JBrowse link
G CLOCK clock circadian regulator involved_in ISS
IEA		 UniProt
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:55,427,903...55,546,909
Ensembl chr 4:55,427,903...55,546,909 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in IMP (PMID:19258434) CACAO
CACAO		 PMID:19258434 NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120 		JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:55682|PMID:6194978), (MGI:63474|PMID:6116352) Ensembl
Ensembl
MGI		 PMID:6116352 PMID:6194978 GO_REF:0000107 MGI:55682 MGI:63474 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:3664138|PMID:17015435) MGI PMID:17015435 MGI:3664138 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:80537|PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G PITX2 paired like homeodomain 2 involved_in TAS (PMID:10372733) BHF-UCL
BHF-UCL		 PMID:10372733 NCBI chr 4:110,617,423...110,642,123
Ensembl chr 4:110,617,423...110,642,123 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:55682|PMID:6194978), (MGI:80583|PMID:1334535) MGI PMID:1334535 PMID:6194978 MGI:55682 MGI:80583 NCBI chr 3:87,259,404...87,276,584
Ensembl chr 3:87,259,404...87,276,584 		JBrowse link
G PROP1 PROP paired-like homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:55682|PMID:6194978) MGI
Ensembl
Ensembl		 PMID:6194978 GO_REF:0000107 MGI:55682 NCBI chr 5:177,992,235...177,996,242
Ensembl chr 5:177,992,235...177,996,242 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3777488|PMID:18351662) Ensembl
Ensembl
MGI		 PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
thyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1316794|PMID:12114718) MGI
Ensembl
Ensembl		 PMID:12114718 GO_REF:0000107 MGI:1316794 NCBI chr 6:87,085,498...87,095,106
Ensembl chr 6:87,085,498...87,095,106 		JBrowse link
G DUOX2 dual oxidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3712355|PMID:17440044) Ensembl
Ensembl
MGI		 PMID:17440044 GO_REF:0000107 MGI:3712355 NCBI chr15:45,092,650...45,114,172
Ensembl chr15:45,092,650...45,114,172 		JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3688470|PMID:11062007) Ensembl
Ensembl
MGI		 PMID:11062007 GO_REF:0000107 MGI:3688470 NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706 		JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3848569|PMID:19389367) Ensembl
Ensembl
MGI		 PMID:19389367 GO_REF:0000107 MGI:3848569 NCBI chr10:101,770,109...101,780,369
Ensembl chr10:101,770,109...101,780,371 		JBrowse link
G FOXE1 forkhead box E1 involved_in
acts_upstream_of_or_within		 IEP
IEA
IMP
ISO		 (PMID:15494458)
(PMID:9697705)
(MGI:1276273|PMID:9697704)		 UniProt
UniProt
Ensembl
MGI		 PMID:9697704 PMID:9697705 PMID:15494458 GO_REF:0000107 MGI:1276273 NCBI chr 9:97,853,226...97,856,717
Ensembl chr 9:97,853,226...97,856,717 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3821506|PMID:18775421) Ensembl
Ensembl
MGI		 PMID:18775421 GO_REF:0000107 MGI:3821506 NCBI chr 3:57,197,838...57,227,615
Ensembl chr 3:57,197,838...57,227,606 		JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1855906|PMID:10804184), (MGI:3522522|PMID:15581879) MGI PMID:10804184 PMID:15581879 MGI:1855906 MGI:3522522 NCBI chr10:92,689,955...92,695,647
Ensembl chr10:92,689,955...92,695,647 		JBrowse link
G HOXA3 homeobox A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1197395|PMID:9524238)
(MGI:1201272|PMID:9520319), (MGI:74186|PMID:7635047)		 Ensembl
MGI
Ensembl		 PMID:7635047 PMID:9520319 PMID:9524238 GO_REF:0000107 MGI:1197395 MGI:1201272 MGI:74186 NCBI chr 7:27,107,010...27,152,583
Ensembl chr 7:27,106,184...27,152,583 		JBrowse link
G HOXA5 homeobox A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2667733|PMID:12815622) Ensembl
Ensembl
MGI		 PMID:12815622 GO_REF:0000107 MGI:2667733 NCBI chr 7:27,141,052...27,143,681
Ensembl chr 7:27,141,052...27,143,681 		JBrowse link
G HOXB3 homeobox B3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1201272|PMID:9520319) Ensembl
Ensembl
MGI		 PMID:9520319 GO_REF:0000107 MGI:1201272 NCBI chr17:48,548,870...48,590,241
Ensembl chr17:48,548,870...48,604,912 		JBrowse link
G HOXD3 homeobox D3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:1201272|PMID:9520319) UniProt
Ensembl
UniProt
MGI		 PMID:9520319 GO_REF:0000024 GO_REF:0000107 MGI:1201272 NCBI chr 2:176,152,529...176,173,098
Ensembl chr 2:176,136,612...176,173,102 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3832113|PMID:18952847) MGI
Ensembl		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEP
IEA
ISO
IMP		 (PMID:15494458)
(MGI:3652637|PMID:16601074)
(PMID:11854319)
(MGI:3769976|PMID:16150900)
(MGI:3522522|PMID:15581879)		 UniProt
Ensembl
MGI
UniProt		 PMID:11854319 PMID:15494458 PMID:15581879 PMID:16150900 PMID:16601074 GO_REF:0000107 MGI:3522522 MGI:3652637 MGI:3769976 NCBI chr14:36,516,397...36,520,232
Ensembl chr14:36,516,392...36,521,149 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IMP
IEA		 (PMID:16418214) BHF-UCL
BHF-UCL
Ensembl		 PMID:16418214 GO_REF:0000107 NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311 		JBrowse link
G PAX8 paired box 8 involved_in
acts_upstream_of_or_within		 IMP
IEP
IEA
ISO		 (PMID:9590296)
(PMID:1337742), (PMID:15494458)
(PMID:1723950)
(MGI:2156109|PMID:11773436)
(MGI:1203285|PMID:9590297)		 UniProt
UniProt
Ensembl
UniProt
MGI		 PMID:1337742 PMID:1723950 PMID:9590296 PMID:9590297 PMID:11773436 More... GO_REF:0000107 MGI:1203285 MGI:2156109 NCBI chr 2:113,215,997...113,278,921
Ensembl chr 2:113,215,997...113,278,921 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3702792|PMID:16968815) Ensembl
Ensembl
MGI		 PMID:16968815 GO_REF:0000107 MGI:3702792 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SIX1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:3624596|PMID:16530750) UniProt
UniProt
Ensembl
MGI		 PMID:16530750 GO_REF:0000024 GO_REF:0000107 MGI:3624596 NCBI chr14:60,643,421...60,649,477
Ensembl chr14:60,643,421...60,658,259 		JBrowse link
G SIX3 SIX homeobox 3 acts_upstream_of_or_within ISO (MGI:3821506|PMID:18775421) MGI PMID:18775421 MGI:3821506 NCBI chr 2:44,941,702...44,946,071
Ensembl chr 2:44,941,702...44,946,071 		JBrowse link
G SMAD3 SMAD family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3618021|PMID:15183723) Ensembl
Ensembl
MGI		 PMID:15183723 GO_REF:0000107 MGI:3618021 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SRF serum response factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506 		JBrowse link
G TBX1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (MGI:3848569|PMID:19389367)
(MGI:3050165|PMID:15190012), (MGI:3697808|PMID:17164259)		 UniProt
UniProt
MGI		 PMID:15190012 PMID:17164259 PMID:19389367 GO_REF:0000024 MGI:3050165 MGI:3697808 MGI:3848569 NCBI chr22:19,756,703...19,783,593
Ensembl chr22:19,756,703...19,783,593 		JBrowse link
G TG thyroglobulin involved_in IEP (PMID:15494458) UniProt
UniProt		 PMID:15494458 NCBI chr 8:132,866,958...133,134,899
Ensembl chr 8:132,866,958...133,134,903 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:18554691 RGD:2302084 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G THRA thyroid hormone receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2156109|PMID:11773436) Ensembl
Ensembl
MGI		 PMID:11773436 GO_REF:0000107 MGI:2156109 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867 		JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (MGI:1202291|PMID:9463347) UniProt
Ensembl
UniProt
MGI		 PMID:9463347 GO_REF:0000024 GO_REF:0000107 MGI:1202291 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202291|PMID:9463347) MGI
Ensembl
Ensembl		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,708...122,898,236 		JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1202291|PMID:9463347) Ensembl
Ensembl
MGI		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr10:101,770,109...101,780,369
Ensembl chr10:101,770,109...101,780,371 		JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3625416|PMID:16543408) MGI
Ensembl		 PMID:16543408 GO_REF:0000107 MGI:3625416 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:80537|PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3777488|PMID:18351662) Ensembl
Ensembl
MGI		 PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IDA (PMID:11865031) BHF-UCL
BHF-UCL		 PMID:11865031 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IDA (PMID:11865031) BHF-UCL
BHF-UCL		 PMID:11865031 NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IDA (PMID:11865031) BHF-UCL
BHF-UCL		 PMID:11865031 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G CDH2 cadherin 2 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in IDA (PMID:20668294) UniProt
UniProt		 PMID:20668294 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:170,282,206...170,291,078
Ensembl chr 6:170,282,206...170,306,565 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr20:44,355,699...44,434,596
Ensembl chr20:44,355,700...44,432,845 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3655758|PMID:16951258) Ensembl
Ensembl
MGI		 PMID:16951258 GO_REF:0000107 MGI:3655758 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
G MIR214 microRNA 214 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:3775688 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MIR375 microRNA 375 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:3775688 NCBI chr 2:219,001,645...219,001,708
Ensembl chr 2:219,001,645...219,001,708 		JBrowse link
G MIR503 microRNA 503 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:3775688 NCBI chr  X:134,546,328...134,546,398
Ensembl chr  X:134,546,328...134,546,398 		JBrowse link
G MIR541 microRNA 541 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3775688|PMID:17804764) MGI
RNAcentral		 PMID:17804764 GO_REF:0000115 MGI:3775688 NCBI chr14:101,064,495...101,064,578
Ensembl chr14:101,064,495...101,064,578 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3703458|PMID:17202186)
(MGI:3761395|PMID:17456846)		 Ensembl
Ensembl
MGI		 PMID:17202186 PMID:17456846 GO_REF:0000107 MGI:3703458 MGI:3761395 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:9603781 GO_REF:0000107 RGD:2326025 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188 		JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5529865|PMID:23776622) Ensembl
Ensembl
MGI		 PMID:23776622 GO_REF:0000107 MGI:5529865 NCBI chr11:117,178,743...117,197,442
Ensembl chr11:117,178,736...117,197,445 		JBrowse link
G SMO smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4833770|PMID:20185815) Ensembl
Ensembl
MGI		 PMID:20185815 GO_REF:0000107 MGI:4833770 NCBI chr 7:129,188,633...129,213,545
Ensembl chr 7:129,188,633...129,213,545 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3663526|PMID:16246260) Ensembl
Ensembl
MGI		 PMID:16246260 GO_REF:0000107 MGI:3663526 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3701716|PMID:16887115) Ensembl
Ensembl
MGI		 PMID:16887115 GO_REF:0000107 MGI:3701716 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (MGI:3619850|PMID:16511571) UniProt
MGI
Ensembl
UniProt		 PMID:16511571 GO_REF:0000024 GO_REF:0000107 MGI:3619850 NCBI chr20:20,368,104...20,370,949
Ensembl chr20:20,368,104...20,370,949 		JBrowse link
G MEN1 menin 1 involved_in IEA
ISO		 Ensembl
Ensembl
RGD		 PMID:24157940 GO_REF:0000107 RGD:9589069 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G MIR7-1 microRNA 7-1 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) MGI PMID:22764048 MGI:5437569 NCBI chr 9:83,969,748...83,969,857
Ensembl chr 9:83,969,748...83,969,857 		JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:2686854|PMID:14729487) MGI
Ensembl		 PMID:14729487 GO_REF:0000107 MGI:2686854 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3579924|PMID:15944193) InterPro
Ensembl
MGI
InterPro		 PMID:15944193 GO_REF:0000002 GO_REF:0000107 MGI:3579924 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859126|PMID:10825208) MGI
Ensembl		 PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078 		JBrowse link
G PAX4 paired box 4 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:2686854|PMID:14729487) MGI
Ensembl		 PMID:14729487 GO_REF:0000107 MGI:2686854 NCBI chr 7:127,610,292...127,618,142
Ensembl chr 7:127,610,292...127,618,142 		JBrowse link
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5437569|PMID:22764048) Ensembl
Ensembl
MGI
RGD		 PMID:22403172 PMID:22764048 GO_REF:0000107 MGI:5437569 RGD:8552355 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within		 IDA
IEA
ISO
IBA
ISS		 (PMID:12124776), (PMID:24567802)
(MGI:3612374|PMID:16418487)
(PMID:21873635)		 CACAO
Ensembl
MGI
GO_Central
BHF-UCL
CACAO
BHF-UCL
GO_Central		 PMID:12124776 PMID:16418487 PMID:21873635 PMID:24567802 GO_REF:0000024 GO_REF:0000107 MGI:3612374 NCBI chr13:27,920,000...27,926,313
Ensembl chr13:27,920,000...27,926,313 		JBrowse link
G REG1A regenerating family member 1 alpha involved_in ISO (MGI:3615755|PMID:16405968) MGI PMID:16405968 MGI:3615755 NCBI chr 2:79,120,488...79,123,409
Ensembl chr 2:79,120,362...79,123,409 		JBrowse link
G RFX6 regulatory factor X6 involved_in ISS
IEA		 UniProt
UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:116,877,242...116,932,161
Ensembl chr 6:116,877,212...116,932,161 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO (MGI:5618205|PMID:25186293) MGI PMID:25186293 MGI:5618205 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,667 		JBrowse link
G ZBED6 zinc finger BED-type containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:203,795,623...203,854,124
Ensembl chr 1:203,795,714...203,854,999 		JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3703458|PMID:17202186), (MGI:3768695|PMID:17988662) Ensembl
Ensembl
MGI		 PMID:17202186 PMID:17988662 GO_REF:0000107 MGI:3703458 MGI:3768695 NCBI chr20:21,511,017...21,522,689
Ensembl chr20:21,511,017...21,514,064 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3611530|PMID:16423820) MGI
Ensembl		 PMID:16423820 GO_REF:0000107 MGI:3611530 NCBI chr 7:98,211,439...98,215,457
Ensembl chr 7:98,211,439...98,215,457 		JBrowse link
G GDF11 growth differentiation factor 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3512831|PMID:15548585) MGI
Ensembl		 PMID:15548585 GO_REF:0000107 MGI:3512831 NCBI chr12:55,743,122...55,757,264
Ensembl chr12:55,743,122...55,757,264 		JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in ISS BHF-UCL
BHF-UCL		 GO_REF:0000024 NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 9:3,218,297...3,526,001
Ensembl chr 9:3,218,297...3,526,004 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19656
    multicellular organismal process 8652
      multicellular organism development 5796
        system development 5325
          endocrine system development 178
            adrenal gland development + 43
            endocrine pancreas development + 61
            parathyroid gland development + 7
            pineal gland development 0
            pituitary gland development + 50
            ring gland development 0
            thyroid gland development + 36
Path 2
Term Annotations click to browse term
  biological_process 19656
    developmental process 7517
      anatomical structure development 6877
        multicellular organism development 5796
          system development 5325
            endocrine system development 178
              adrenal gland development + 43
              endocrine pancreas development + 61
              parathyroid gland development + 7
              pineal gland development 0
              pituitary gland development + 50
              ring gland development 0
              thyroid gland development + 36
paths to the root