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ONTOLOGY REPORT - ANNOTATIONS


Term:endocrine system development
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Accession:GO:0035270 term browser browse the term
Definition:Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.



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endocrine system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3655758|PMID:16951258) MGI PMID:16951258 MGI:3655758 NCBI chr24:3,008,387...3,011,186 JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3576468|PMID:9140068) MGI
Ensembl
Ensembl
PMID:9140068 GO_REF:0000107 MGI:3576468 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241
JBrowse link
G GHRH growth hormone releasing hormone acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3607618|PMID:15985453) MGI
Ensembl
Ensembl
PMID:15985453 GO_REF:0000107 MGI:3607618 NCBI chr24:25,893,224...25,902,095
Ensembl chr24:25,893,225...25,897,712
JBrowse link
G GHRHR growth hormone releasing hormone receptor acts_upstream_of_or_within ISO (MGI:51713|PMID:1504465), (MGI:54124|PMID:1270792), (MGI:63703|PMID:1329576) MGI PMID:1270792 PMID:1329576 PMID:1504465 MGI:51713 MGI:54124 MGI:63703 NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753
JBrowse link
G GSX1 GS homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:79250|PMID:8631293) Ensembl
Ensembl
MGI
PMID:8631293 GO_REF:0000107 MGI:79250 NCBI chr25:11,853,483...11,855,169
Ensembl chr25:11,853,462...11,855,445
JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:3827091|PMID:18996108) MGI PMID:18996108 MGI:3827091
G POU1F1 POU class 1 homeobox 1 ISO RGD PMID:16216912 RGD:1601440 NCBI chr31:769,454...788,761
Ensembl chr31:769,487...787,626
JBrowse link
G PROP1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO (MGI:3827091|PMID:18996108) MGI PMID:18996108 MGI:3827091 NCBI chr11:2,739,958...2,742,576
Ensembl chr11:2,739,958...2,743,533
JBrowse link
G SLC6A3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO (MGI:894559|PMID:9247269) MGI PMID:9247269 MGI:894559 NCBI chr34:11,209,118...11,245,456
Ensembl chr34:11,210,939...11,246,742
JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (MGI:3689142|PMID:16932809) RGD
MGI
PMID:16932809 PMID:21815952 MGI:3689142 RGD:8661681 NCBI chr34:14,853,000...14,855,153 JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOX2 dual oxidase 2 acts_upstream_of_or_within ISO (MGI:3712355|PMID:17440044) MGI PMID:17440044 MGI:3712355 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716
JBrowse link
adrenal chromaffin cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:2387977|PMID:12361965) MGI PMID:12361965 MGI:2387977 NCBI chr15:41,694,021...41,696,933
Ensembl chr15:41,694,269...41,695,391
JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) UniProt PMID:18094025 MGI:3772428 NCBI chr24:3,008,387...3,011,186 JBrowse link
adrenal cortex development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC5 armadillo repeat containing 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5913685|PMID:28911199) MGI
Ensembl
PMID:28911199 GO_REF:0000107 MGI:5913685 NCBI chr 6:16,782,732...16,789,490
Ensembl chr 6:16,781,860...16,788,878
JBrowse link
adrenal cortex formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in ISO (MGI:3790398|PMID:17537799) UniProt PMID:17537799 MGI:3790398 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995
JBrowse link
G WT1 WT1 transcription factor involved_in ISO (MGI:3790398|PMID:17537799) UniProt PMID:17537799 MGI:3790398 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
JBrowse link
adrenal gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2A activin A receptor type 2A ISO RGD PMID:12844345 RGD:728125 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420
JBrowse link
G ACVR2B activin A receptor type 2B ISO RGD PMID:12844345 RGD:728125 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894
JBrowse link
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2180727|PMID:8647961) Ensembl
Ensembl
MGI
PMID:8647961 GO_REF:0000107 MGI:2180727 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943
JBrowse link
G ARID5B AT-rich interaction domain 5B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2137956|PMID:11483573) Ensembl
MGI
PMID:11483573 GO_REF:0000107 MGI:2137956 NCBI chr 4:13,926,759...14,105,069
Ensembl chr 4:13,927,217...14,101,364
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C acts_upstream_of_or_within ISO (MGI:3839493|PMID:19276117) MGI PMID:19276117 MGI:3839493 NCBI chr18:46,860,636...46,861,697 JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 acts_upstream_of_or_within ISO (MGI:2179743|PMID:11694877), (MGI:3606737|PMID:15615595) MGI PMID:11694877 PMID:15615595 MGI:2179743 MGI:3606737 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995
JBrowse link
G CRH corticotropin releasing hormone acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1860037|PMID:10861000) MGI
Ensembl
Ensembl
PMID:10861000 GO_REF:0000107 MGI:1860037 NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 ISO RGD PMID:7829497 RGD:1299585 NCBI chr13:36,866,476...36,880,625 JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO RGD PMID:17065412 RGD:4889133 NCBI chr28:15,292,959...15,298,896
Ensembl chr28:15,293,106...15,298,852
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:8097866 RGD:4145970 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:10098502 RGD:7829725 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554
JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:35,032,501...35,074,664
Ensembl chr21:35,033,552...35,074,664
JBrowse link
G FDX1 ferredoxin 1 ISO RGD PMID:8097866 RGD:4145970 NCBI chr 5:22,452,011...22,485,581
Ensembl chr 5:22,451,209...22,485,395
JBrowse link
G FSTL3 follistatin like 3 ISO RGD PMID:14692692 RGD:1302294 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172
JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:69334|PMID:7958830) MGI PMID:7958830 MGI:69334 NCBI chr10:8,348,101...8,491,435 JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO (MGI:5493430|PMID:23300479) CACAO PMID:23300479 MGI:5493430 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387
JBrowse link
G INSR insulin receptor involved_in ISO (MGI:5493430|PMID:23300479) CACAO PMID:23300479 MGI:5493430 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046
JBrowse link
G LOC491316 midkine involved_in ISO PMID:11136554 UniProt PMID:11136554 RGD:62414 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G LY6E lymphocyte antigen 6 family member E acts_upstream_of_or_within ISO (MGI:2157257|PMID:11784869) MGI PMID:11784869 MGI:2157257 NCBI chr13:36,926,776...36,930,265
Ensembl chr13:36,925,980...36,974,979
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:3689139|PMID:16906226) MGI PMID:16906226 MGI:3689139 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:2159510|PMID:11796523)
(PMID:21873635)
MGI
GO_Central
PMID:11796523 PMID:21873635 MGI:2159510 NCBI chr  X:25,396,527...25,401,587
Ensembl chr  X:25,396,527...25,401,715
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:74913|PMID:7628695) MGI
Ensembl
PMID:7628695 GO_REF:0000107 MGI:74913 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755
JBrowse link
G PBX1 PBX homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2683990|PMID:14595835) MGI
Ensembl
Ensembl
PMID:14595835 GO_REF:0000107 MGI:2683990 NCBI chr38:18,378,997...18,703,694
Ensembl chr38:18,418,093...18,703,497
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3820330|PMID:19056881) Ensembl
MGI
PMID:19056881 GO_REF:0000107 MGI:3820330 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278
JBrowse link
G PDGFRB platelet derived growth factor receptor beta acts_upstream_of_or_within ISO (MGI:3820330|PMID:19056881) MGI PMID:19056881 MGI:3820330 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283
JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:16140489 RGD:5130728 NCBI chr 9:22,808,505...22,810,587
Ensembl chr 9:22,808,601...22,810,551
JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:64,242,742...64,260,021
Ensembl chr 2:64,243,987...64,259,521
JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:12844345 RGD:728125 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983
JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:12844345 RGD:728125 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337
JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:12844345 RGD:728125 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405
JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 involved_in ISO (PMID:17273977) DFLAT PMID:17273977 NCBI chr30:37,331,834...37,359,449
Ensembl chr30:37,331,832...37,353,529
JBrowse link
G THRA thyroid hormone receptor alpha ISO RGD PMID:17496154 RGD:2314319 NCBI chr 9:22,469,466...22,493,445
Ensembl chr 9:22,468,594...22,493,445
JBrowse link
G TSPO translocator protein ISO RGD PMID:9927316 RGD:2317174 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297
JBrowse link
G WNT11 Wnt family member 11 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr21:22,442,496...22,463,040
Ensembl chr21:22,446,051...22,463,173
JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
G WT1 WT1 transcription factor involved_in ISO (PMID:10101119)
(MGI:1333093|PMID:10101119)
UniProt PMID:10101119 MGI:1333093 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151
JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468
JBrowse link
endocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:7527053 PMID:21873635 RGD:2306957 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011
JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO RGD PMID:11000281 RGD:2315710 NCBI chr12:2,950,359...2,957,604
Ensembl chr12:2,948,364...2,957,018
JBrowse link
G CLU clusterin ISO RGD PMID:16411126 RGD:1582421 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within
involved_in
ISO (MGI:3530180|PMID:15680365)
(PMID:12124776)
MGI
BHF-UCL
PMID:12124776 PMID:15680365 MGI:3530180 NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072
JBrowse link
G GIP gastric inhibitory polypeptide acts_upstream_of_or_within ISO (MGI:4940930|PMID:21270265) MGI PMID:21270265 MGI:4940930 NCBI chr 9:25,167,938...25,174,402
Ensembl chr 9:25,167,926...25,174,575
JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4940930|PMID:21270265) Ensembl
Ensembl
MGI
PMID:21270265 GO_REF:0000107 MGI:4940930 NCBI chr 1:109,898,617...109,909,331
Ensembl chr 1:109,899,874...109,909,410
JBrowse link
G HNF1A HNF1 homeobox A involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,805,690...16,826,065
Ensembl chr26:16,805,690...16,824,790
JBrowse link
G HNF1B HNF1 homeobox B involved_in ISO (PMID:16801329) UniProt PMID:16801329 NCBI chr 9:37,437,992...37,493,200
Ensembl chr 9:37,438,583...37,492,993
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:3807360|PMID:18719127) BHF-UCL PMID:18719127 MGI:3807360 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090
JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3619850|PMID:16511571) MGI PMID:16511571 MGI:3619850 NCBI chr24:3,008,387...3,011,186 JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1344214|PMID:10471501)
(PMID:21873635)
MGI
GO_Central
PMID:10471501 PMID:21873635 MGI:1344214 NCBI chr16:19,509,038...19,514,378
Ensembl chr16:19,499,582...19,512,836
JBrowse link
G MYT1 myelin transcription factor 1 acts_upstream_of_or_within ISO (MGI:3763794|PMID:17928203) MGI PMID:17928203 MGI:3763794 NCBI chr24:47,574,201...47,639,962
Ensembl chr24:47,574,255...47,638,315
JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in ISO (MGI:1096974|PMID:9308961), (MGI:1352314|PMID:10639171) BHF-UCL PMID:9308961 PMID:10639171 MGI:1096974 MGI:1352314 NCBI chr36:24,853,591...24,857,886 JBrowse link
G NEUROG3 neurogenin 3 involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr 4:20,654,824...20,657,816
Ensembl chr 4:20,656,791...20,657,438
JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:1270972|PMID:9584121) MGI PMID:9584121 MGI:1270972 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874
JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3579924|PMID:15944193) MGI
Ensembl
PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr32:8,256,513...8,263,238
Ensembl chr32:8,256,254...8,262,004
JBrowse link
G NKX6-2 NK6 homeobox 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3579924|PMID:15944193) MGI
Ensembl
Ensembl
PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr28:40,568,948...40,570,240
Ensembl chr28:40,569,093...40,570,793
JBrowse link
G ONECUT1 one cut homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3710726|PMID:17400205) Ensembl
Ensembl
MGI
PMID:17400205 GO_REF:0000107 MGI:3710726 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497
JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (MGI:3710726|PMID:17400205) MGI PMID:17400205 MGI:3710726 NCBI chr 1:18,428,112...18,486,047
Ensembl chr 1:18,440,172...18,486,048
JBrowse link
G PDE3B phosphodiesterase 3B acts_upstream_of_or_within ISO (MGI:3040550|PMID:14736883) MGI PMID:14736883 MGI:3040550 NCBI chr21:37,364,940...37,532,152
Ensembl chr21:37,364,623...37,530,597
JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3771560|PMID:18155690) MGI
Ensembl
PMID:18155690 GO_REF:0000107 MGI:3771560 NCBI chr25:11,741,863...11,746,885
Ensembl chr25:11,741,863...11,746,885
JBrowse link
G RFX3 regulatory factor X3 involved_in ISO (MGI:3713191|PMID:17229940) UniProt PMID:17229940 MGI:3713191 NCBI chr 1:91,773,492...92,060,895
Ensembl chr 1:91,778,481...92,059,792
JBrowse link
G RFX6 regulatory factor X6 involved_in ISO (PMID:20148032) UniProt PMID:20148032 NCBI chr 1:57,242,563...57,297,300
Ensembl chr 1:57,241,927...57,296,546
JBrowse link
G SOX4 SRY-box transcription factor 4 acts_upstream_of_or_within ISO (MGI:3611650|PMID:16306355) MGI PMID:16306355 MGI:3611650 NCBI chr35:20,098,783...20,101,357
Ensembl chr35:20,099,773...20,101,154
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3815251|PMID:18723011) MGI PMID:18723011 MGI:3815251 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PROP1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO (MGI:3690195|PMID:16678101) MGI PMID:16678101 MGI:3690195 NCBI chr11:2,739,958...2,742,576
Ensembl chr11:2,739,958...2,743,533
JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3043884|PMID:15037319) MGI
Ensembl
Ensembl
PMID:15037319 GO_REF:0000107 MGI:3043884 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:1351379|PMID:10615124) MGI PMID:10615124 MGI:1351379
G MIR7-1 microRNA mir-7-1 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) MGI PMID:22764048 MGI:5437569 NCBI chr 1:75,509,765...75,509,828
Ensembl chr 1:75,509,743...75,509,851
JBrowse link
negative regulation of thyroid gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC487387 RAP1 GTPase activating protein ISO RGD PMID:17646383 RGD:9835038 NCBI chr 2:77,509,592...77,554,620
Ensembl chr 2:77,527,914...77,544,205
JBrowse link
G MIR1-2 microRNA mir-1-2 ISO RGD PMID:21816899 RGD:10059418 NCBI chr 7:66,214,380...66,214,438
Ensembl chr 7:66,214,366...66,214,450
JBrowse link
G MIR28 microRNA mir-28 ISO RGD PMID:21816899 RGD:10059418 NCBI chr34:20,971,517...20,971,578
Ensembl chr34:20,971,504...20,971,589
JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTP orthopedia homeobox acts_upstream_of_or_within ISO (MGI:1347696|PMID:10557207) MGI PMID:10557207 MGI:1347696 NCBI chr 3:29,063,359...29,071,533
Ensembl chr 3:29,064,681...29,071,509
JBrowse link
G POU3F2 POU class 3 homeobox 2 acts_upstream_of_or_within ISO (MGI:77941|PMID:8543156) MGI PMID:8543156 MGI:77941 NCBI chr12:57,103,712...57,108,522 JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in ISO PMID:20592023
(MGI:4943812|PMID:20592023)
(PMID:20592023)
BHF-UCL PMID:20592023 MGI:4943812 RGD:8552352
pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (MGI:3701716|PMID:16887115) MGI PMID:16887115 MGI:3701716 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of ISO (MGI:1351379|PMID:10615124) MGI PMID:10615124 MGI:1351379
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within
ISO (MGI:3619850|PMID:16511571) UniProt
MGI
PMID:16511571 MGI:3619850 NCBI chr24:3,008,387...3,011,186 JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3579924|PMID:15944193) MGI
Ensembl
PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr32:8,256,513...8,263,238
Ensembl chr32:8,256,254...8,262,004
JBrowse link
G NKX6-2 NK6 homeobox 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3579924|PMID:15944193) MGI
Ensembl
PMID:15944193 GO_REF:0000107 MGI:3579924 NCBI chr28:40,568,948...40,570,240
Ensembl chr28:40,569,093...40,570,793
JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1859126|PMID:10825208) MGI
Ensembl
PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497
JBrowse link
G PAX6 paired box 6 ISO RGD PMID:20592023 RGD:8552352
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,242,563...57,297,300
Ensembl chr 1:57,241,927...57,296,546
JBrowse link
G VHL von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO (MGI:5618205|PMID:25186293) MGI PMID:25186293 MGI:5618205 NCBI chr20:8,206,616...8,211,347
Ensembl chr20:8,206,616...8,211,323
JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 acts_upstream_of_or_within ISO (MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:3768695 NCBI chr36:24,853,591...24,857,886 JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:3768695|PMID:17988662)
(MGI:3703458|PMID:17202186)
MGI PMID:17202186 PMID:17988662 MGI:3703458 MGI:3768695 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874
JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1859126|PMID:10825208) MGI
Ensembl
PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497
JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,242,563...57,297,300
Ensembl chr 1:57,241,927...57,296,546
JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,242,563...57,297,300
Ensembl chr 1:57,241,927...57,296,546
JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 acts_upstream_of_or_within ISO (MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:3768695 NCBI chr36:24,853,591...24,857,886 JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:3768695 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874
JBrowse link
parathyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3614586|PMID:16399080) Ensembl
Ensembl
MGI
PMID:16399080 GO_REF:0000107 MGI:3614586 NCBI chr26:30,542,276...30,582,479
Ensembl chr26:30,545,311...30,581,964
JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:4460059|PMID:20484821) MGI PMID:20484821 MGI:4460059 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760
JBrowse link
G GCM2 glial cells missing transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5780847|PMID:19968565) Ensembl
Ensembl
MGI
PMID:19968565 GO_REF:0000107 MGI:5780847 NCBI chr35:10,561,245...10,568,351
Ensembl chr35:10,561,514...10,568,106
JBrowse link
G HOXA3 homeobox A3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2149273|PMID:11476574) Ensembl
Ensembl
MGI
PMID:11476574 GO_REF:0000107 MGI:2149273 NCBI chr14:40,280,866...40,326,559
Ensembl chr14:40,280,861...40,296,147
JBrowse link
G PAX1 paired box 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2149273|PMID:11476574) MGI
Ensembl
Ensembl
PMID:11476574 GO_REF:0000107 MGI:2149273 NCBI chr24:1,742,570...1,752,593
Ensembl chr24:1,743,940...1,753,185
JBrowse link
G TBX1 T-box transcription factor 1 involved_in ISO (PMID:14585638) UniProt PMID:14585638 NCBI chr26:29,529,071...29,533,240
Ensembl chr26:29,528,878...29,532,784
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3703113|PMID:17078885) Ensembl
MGI
PMID:17078885 GO_REF:0000107 MGI:3703113 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594
JBrowse link
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:18160680 RGD:2325274 NCBI chr 7:67,682,421...67,691,035 JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 ISO RGD PMID:17180597 RGD:2306413 NCBI chr30:23,074,432...23,170,374
Ensembl chr30:23,074,432...23,340,030
JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 ISO RGD PMID:17180597 RGD:2306413 NCBI chr 3:40,130,904...40,168,686
Ensembl chr 3:40,132,726...40,168,664
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1306869|PMID:9806931) Ensembl
Ensembl
MGI
PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3709795|PMID:17359964) Ensembl
Ensembl
MGI
PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923
JBrowse link
G CDH1 cadherin 1 ISO RGD PMID:17373711 RGD:2289637 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878
JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3611103|PMID:16141355) Ensembl
MGI
Ensembl
PMID:16141355 GO_REF:0000107 MGI:3611103 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556
JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO RGD PMID:8946059 RGD:2313681 NCBI chr 5:6,059,023...6,189,516
Ensembl chr 5:6,058,935...6,186,232
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3688470|PMID:11062007) Ensembl
Ensembl
MGI
PMID:11062007 GO_REF:0000107 MGI:3688470 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192
JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within ISO (MGI:3625416|PMID:16543408) MGI PMID:16543408 MGI:3625416 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991
JBrowse link
G GLI1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1354188|PMID:10725236) Ensembl
Ensembl
InterPro
InterPro
MGI
PMID:10725236 GO_REF:0000002 GO_REF:0000107 MGI:1354188 NCBI chr10:1,565,306...1,575,971
Ensembl chr10:1,565,244...1,575,982
JBrowse link
G GLI2 GLI family zinc finger 2 acts_upstream_of_or_within ISO (MGI:1354188|PMID:10725236) MGI PMID:10725236 MGI:1354188 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658
JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO (MGI:3712393|PMID:17426285)
(MGI:3664138|PMID:17015435), (MGI:3712393|PMID:17426285)
MGI PMID:17015435 PMID:17426285 MGI:3664138 MGI:3712393
G HESX1 HESX homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1206234|PMID:9620767), (MGI:2154557|PMID:11731482)
(MGI:3821905|PMID:19093031)
(PMID:21873635)
(MGI:4440397|PMID:20181723)
(MGI:3821506|PMID:18775421)
MGI
GO_Central
PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 More... MGI:1206234 MGI:2154557 MGI:3821506 MGI:3821905 MGI:4440397 NCBI chr20:33,193,813...33,197,226
Ensembl chr20:33,195,123...33,196,601
JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:54708|PMID:504232) MGI PMID:504232 MGI:54708 NCBI chr10:8,348,101...8,491,435 JBrowse link
G INHBB inhibin subunit beta B ISO RGD PMID:18160680 RGD:2325274 NCBI chr19:29,765,697...29,768,485
Ensembl chr19:29,767,682...29,768,077
JBrowse link
G ISL1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO (MGI:1306869|PMID:9806931) MGI PMID:9806931 MGI:1306869 NCBI chr 4:63,638,009...63,648,492
Ensembl chr 4:63,637,443...63,648,183
JBrowse link
G KDM1A lysine demethylase 1A acts_upstream_of_or_within ISO (MGI:3710033|PMID:17392792) MGI PMID:17392792 MGI:3710033 NCBI chr 2:76,313,742...76,375,716
Ensembl chr 2:76,156,434...76,375,632
JBrowse link
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3771226|PMID:18037398) MGI
Ensembl
PMID:18037398 GO_REF:0000107 MGI:3771226 NCBI chr 9:49,248,555...49,254,128
Ensembl chr 9:49,248,621...49,254,118
JBrowse link
G MSX1 msh homeobox 1 ISO RGD PMID:16451220 RGD:5132608 NCBI chr 3:70,232,790...70,236,295
Ensembl chr 3:70,232,052...70,236,447
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1306869|PMID:9806931) Ensembl
Ensembl
MGI
PMID:9806931 GO_REF:0000107 MGI:1306869
G NOG noggin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3709795|PMID:17359964) MGI
Ensembl
PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NOG noggin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:31,455,389...31,456,057 JBrowse link
G PAX6 paired box 6 acts_upstream_of_or_within ISO (MGI:1350715|PMID:10588713) MGI PMID:10588713 MGI:1350715
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:15208361 RGD:2308902 NCBI chr 3:13,233,342...13,276,921
Ensembl chr 3:13,233,594...13,274,094
JBrowse link
G PITX1 paired like homeodomain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1332284|PMID:10049363) Ensembl
MGI
PMID:10049363 GO_REF:0000107 MGI:1332284 NCBI chr11:23,069,731...23,075,085
Ensembl chr11:23,069,716...23,080,941
JBrowse link
G PITX2 paired like homeodomain 2 acts_upstream_of_or_within ISO (MGI:1345532|PMID:10499586)
(MGI:1344731|PMID:10498698)
MGI PMID:10498698 PMID:10499586 MGI:1344731 MGI:1345532 NCBI chr32:30,710,161...30,730,162
Ensembl chr32:30,710,685...30,730,273
JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3625414|PMID:16556738) MGI
Ensembl
PMID:16556738 GO_REF:0000107 MGI:3625414 NCBI chr31:769,454...788,761
Ensembl chr31:769,487...787,626
JBrowse link
G PROP1 PROP paired-like homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2154557|PMID:11731482) InterPro
InterPro
MGI
PMID:11731482 GO_REF:0000002 MGI:2154557 NCBI chr11:2,739,958...2,742,576
Ensembl chr11:2,739,958...2,743,533
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (MGI:3664138|PMID:17015435) MGI PMID:17015435 MGI:3664138 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360
JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 2:64,242,742...64,260,021
Ensembl chr 2:64,243,987...64,259,521
JBrowse link
G SIX3 SIX homeobox 3 involved_in
acts_upstream_of_or_within
ISO (MGI:3821506|PMID:18775421) UniProt
MGI
PMID:18775421 MGI:3821506 NCBI chr10:47,332,875...47,369,359
Ensembl chr10:47,332,888...47,343,635
JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in ISO (PMID:18285410) UniProt PMID:18285410 NCBI chr34:14,853,000...14,855,153 JBrowse link
G SOX3 SRY-box transcription factor 3 involved_in ISO (MGI:3033563|PMID:14981518) UniProt PMID:14981518 MGI:3033563 NCBI chr  X:110,361,354...110,363,458
Ensembl chr  X:110,362,124...110,363,458
JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO RGD PMID:8770891 RGD:4892048 NCBI chr34:7,118,814...7,144,828
Ensembl chr34:7,118,814...7,144,828
JBrowse link
G TBX19 T-box transcription factor 19 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2137424|PMID:11447259) Ensembl
Ensembl
MGI
PMID:11447259 GO_REF:0000107 MGI:2137424 NCBI chr 7:30,198,912...30,248,410
Ensembl chr 7:30,185,850...30,365,512
JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:3763872|PMID:17919533) MGI PMID:17919533 MGI:3763872 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737
JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405
JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:91,773,492...92,060,895
Ensembl chr 1:91,778,481...92,059,792
JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:80537|PMID:8638120) MGI
Ensembl
PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:49,248,555...49,254,128
Ensembl chr 9:49,248,621...49,254,118
JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:36,254,235...36,323,915
Ensembl chr21:36,290,070...36,323,622
JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr13:47,684,409...47,825,733
Ensembl chr13:47,691,709...47,758,784
JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr16:15,439,910...15,483,489
Ensembl chr16:15,434,111...15,483,419
JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor acts_upstream_of_or_within ISO (MGI:55682|PMID:6194978), (MGI:63474|PMID:6116352) MGI PMID:6116352 PMID:6194978 MGI:55682 MGI:63474 NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753
JBrowse link
G POU1F1 POU class 1 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3664138|PMID:17015435) Ensembl
Ensembl
MGI
PMID:17015435 GO_REF:0000107 MGI:3664138 NCBI chr31:769,454...788,761
Ensembl chr31:769,487...787,626
JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:80537|PMID:8638120) MGI
Ensembl
PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:49,248,555...49,254,128
Ensembl chr 9:49,248,621...49,254,118
JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:55682|PMID:6194978), (MGI:80583|PMID:1334535) MGI
Ensembl
PMID:1334535 PMID:6194978 GO_REF:0000107 MGI:55682 MGI:80583 NCBI chr31:769,454...788,761
Ensembl chr31:769,487...787,626
JBrowse link
G PROP1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO (MGI:55682|PMID:6194978) MGI PMID:6194978 MGI:55682 NCBI chr11:2,739,958...2,742,576
Ensembl chr11:2,739,958...2,743,533
JBrowse link
G WNT4 Wnt family member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3777488|PMID:18351662) MGI
Ensembl
PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
thyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:3832113|PMID:18952847) MGI PMID:18952847 MGI:3832113 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906
JBrowse link
G CGA glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO (MGI:1316794|PMID:12114718) MGI PMID:12114718 MGI:1316794 NCBI chr12:46,610,801...46,629,322
Ensembl chr12:46,610,973...46,636,640
JBrowse link
G DUOX2 dual oxidase 2 acts_upstream_of_or_within ISO (MGI:3712355|PMID:17440044) MGI PMID:17440044 MGI:3712355 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716
JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383
JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr15:45,823,472...45,878,527
Ensembl chr15:45,823,560...45,876,463
JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3688470|PMID:11062007) Ensembl
Ensembl
MGI
PMID:11062007 GO_REF:0000107 MGI:3688470 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192
JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:3848569|PMID:19389367) MGI PMID:19389367 MGI:3848569 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468
JBrowse link
G FOXE1 forkhead box E1 involved_in
acts_upstream_of_or_within
ISO (PMID:15494458)
(MGI:1276273|PMID:9697704)
(PMID:9697705)
UniProt
MGI
PMID:9697704 PMID:9697705 PMID:15494458 MGI:1276273 NCBI chr11:55,143,389...55,145,954 JBrowse link
G HESX1 HESX homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3821506|PMID:18775421) MGI
Ensembl
PMID:18775421 GO_REF:0000107 MGI:3821506 NCBI chr20:33,193,813...33,197,226
Ensembl chr20:33,195,123...33,196,601
JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1855906|PMID:10804184), (MGI:3522522|PMID:15581879) MGI PMID:10804184 PMID:15581879 MGI:1855906 MGI:3522522 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330
JBrowse link
G HOXA3 homeobox A3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1197395|PMID:9524238)
(MGI:1201272|PMID:9520319), (MGI:74186|PMID:7635047)
Ensembl
MGI
Ensembl
PMID:7635047 PMID:9520319 PMID:9524238 GO_REF:0000107 MGI:1197395 MGI:1201272 MGI:74186 NCBI chr14:40,280,866...40,326,559
Ensembl chr14:40,280,861...40,296,147
JBrowse link
G HOXA5 homeobox A5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2667733|PMID:12815622) MGI
Ensembl
Ensembl
PMID:12815622 GO_REF:0000107 MGI:2667733 NCBI chr14:40,315,409...40,319,001
Ensembl chr14:40,315,639...40,317,768
JBrowse link
G HOXB3 homeobox B3 acts_upstream_of_or_within ISO (MGI:1201272|PMID:9520319) MGI PMID:9520319 MGI:1201272 NCBI chr 9:24,810,299...24,837,434
Ensembl chr 9:24,809,739...24,836,058
JBrowse link
G HOXD3 homeobox D3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1201272|PMID:9520319) Ensembl
Ensembl
MGI
PMID:9520319 GO_REF:0000107 MGI:1201272 NCBI chr36:19,961,393...19,981,672
Ensembl chr36:19,960,761...19,980,525
JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3832113|PMID:18952847) MGI
Ensembl
PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 acts_upstream_of_or_within ISO (MGI:3832113|PMID:18952847) MGI PMID:18952847 MGI:3832113 NCBI chr20:55,465,460...55,487,629
Ensembl chr20:55,465,212...55,487,641
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI
PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 acts_upstream_of_or_within ISO (MGI:3832113|PMID:18952847) MGI PMID:18952847 MGI:3832113 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3652637|PMID:16601074)
(MGI:3522522|PMID:15581879)
(MGI:3769976|PMID:16150900)
Ensembl
MGI
Ensembl
PMID:15581879 PMID:16150900 PMID:16601074 GO_REF:0000107 MGI:3522522 MGI:3652637 MGI:3769976
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:39,240,755...39,254,585
Ensembl chr 4:39,244,286...39,247,592
JBrowse link
G PAX8 paired box 8 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:1203285|PMID:9590297)
(PMID:1723950)
(MGI:2156109|PMID:11773436)
UniProt
Ensembl
UniProt
MGI
UniProt
PMID:1723950 PMID:9590297 PMID:11773436 GO_REF:0000024 GO_REF:0000107 MGI:1203285 MGI:2156109 NCBI chr17:37,307,130...37,331,729
Ensembl chr17:37,306,033...37,363,178
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI
PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3702792|PMID:16968815) Ensembl
MGI
PMID:16968815 GO_REF:0000107 MGI:3702792 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SIX1 SIX homeobox 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:3624596|PMID:16530750) UniProt
UniProt
Ensembl
MGI
PMID:16530750 GO_REF:0000024 GO_REF:0000107 MGI:3624596 NCBI chr 8:35,676,705...35,679,534
Ensembl chr 8:35,676,479...35,679,534
JBrowse link
G SIX3 SIX homeobox 3 acts_upstream_of_or_within ISO (MGI:3821506|PMID:18775421) MGI PMID:18775421 MGI:3821506 NCBI chr10:47,332,875...47,369,359
Ensembl chr10:47,332,888...47,343,635
JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3618021|PMID:15183723) MGI
Ensembl
PMID:15183723 GO_REF:0000107 MGI:3618021 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337
JBrowse link
G SRF serum response factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3832113|PMID:18952847) Ensembl
Ensembl
MGI
PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr12:11,664,441...11,673,846
Ensembl chr12:11,664,527...11,671,533
JBrowse link
G TBX1 T-box transcription factor 1 acts_upstream_of_or_within
involved_in
ISO
ISS
(MGI:3848569|PMID:19389367)
(MGI:3050165|PMID:15190012), (MGI:3697808|PMID:17164259)
MGI
UniProt
PMID:15190012 PMID:17164259 PMID:19389367 GO_REF:0000024 MGI:3050165 MGI:3697808 MGI:3848569 NCBI chr26:29,529,071...29,533,240
Ensembl chr26:29,528,878...29,532,784
JBrowse link
G TG thyroglobulin involved_in ISO (PMID:15494458) UniProt PMID:15494458 NCBI chr13:29,350,726...29,597,908
Ensembl chr13:29,350,688...29,598,040
JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:18554691 RGD:2302084 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242
JBrowse link
G THRA thyroid hormone receptor alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2156109|PMID:11773436) MGI
Ensembl
PMID:11773436 GO_REF:0000107 MGI:2156109 NCBI chr 9:22,469,466...22,493,445
Ensembl chr 9:22,468,594...22,493,445
JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151
JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr28:14,362,407...14,367,109
Ensembl chr28:14,362,109...14,367,468
JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within ISO (MGI:3625416|PMID:16543408) MGI PMID:16543408 MGI:3625416 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991
JBrowse link
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:80537|PMID:8638120) MGI
Ensembl
PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:49,248,555...49,254,128
Ensembl chr 9:49,248,621...49,254,118
JBrowse link
G WNT4 Wnt family member 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3777488|PMID:18351662) MGI
Ensembl
PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in ISO (PMID:11865031) BHF-UCL PMID:11865031 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845
JBrowse link
G CDH2 cadherin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,736,760...60,950,477
Ensembl chr 7:60,736,760...60,951,034
JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in ISO (PMID:20668294) UniProt PMID:20668294 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869
JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in ISO (MGI:5426345|PMID:22529374) UniProt PMID:22529374 MGI:5426345 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA InterPro
InterPro
GO_REF:0000002 NCBI chr24:31,847,864...31,908,337
Ensembl chr24:31,847,961...31,905,916
JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3655758|PMID:16951258) MGI PMID:16951258 MGI:3655758 NCBI chr24:3,008,387...3,011,186 JBrowse link
G MIR214 microRNA mir-214 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:3775688 NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670
JBrowse link
G MIR375 microRNA mir-375 acts_upstream_of_or_within ISO (MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:3775688 NCBI chr37:25,568,052...25,568,121
Ensembl chr37:25,568,052...25,568,127
JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:3703458|PMID:17202186)
(MGI:3761395|PMID:17456846)
MGI PMID:17202186 PMID:17456846 MGI:3703458 MGI:3761395 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874
JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr32:8,256,513...8,263,238
Ensembl chr32:8,256,254...8,262,004
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295
JBrowse link
G SIDT2 SID1 transmembrane family member 2 acts_upstream_of_or_within ISO (MGI:5529865|PMID:23776622) MGI PMID:23776622 MGI:5529865 NCBI chr 5:16,397,532...16,410,827
Ensembl chr 5:16,398,815...16,411,268
JBrowse link
G SMO smoothened, frizzled class receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4833770|PMID:20185815) MGI
Ensembl
PMID:20185815 GO_REF:0000107 MGI:4833770 NCBI chr14:7,518,871...7,527,703
Ensembl chr14:7,518,856...7,528,033
JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3663526|PMID:16246260) MGI
Ensembl
Ensembl
PMID:16246260 GO_REF:0000107 MGI:3663526 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673
JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 acts_upstream_of_or_within ISO (MGI:3701716|PMID:16887115) MGI PMID:16887115 MGI:3701716 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within
ISO (MGI:3619850|PMID:16511571) UniProt
MGI
PMID:16511571 MGI:3619850 NCBI chr24:3,008,387...3,011,186 JBrowse link
G MEN1 menin 1 ISO RGD PMID:24157940 RGD:9589069 NCBI chr18:52,346,747...52,352,884
Ensembl chr18:52,346,933...52,353,340
JBrowse link
G MIR7-1 microRNA mir-7-1 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) MGI PMID:22764048 MGI:5437569 NCBI chr 1:75,509,765...75,509,828
Ensembl chr 1:75,509,743...75,509,851
JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of ISO (MGI:2686854|PMID:14729487) MGI PMID:14729487 MGI:2686854 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874
JBrowse link
G NKX6-1 NK6 homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3579924|PMID:15944193) InterPro
Ensembl
MGI
InterPro
PMID:15944193 GO_REF:0000002 GO_REF:0000107 MGI:3579924 NCBI chr32:8,256,513...8,263,238
Ensembl chr32:8,256,254...8,262,004
JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1859126|PMID:10825208) MGI
Ensembl
PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497
JBrowse link
G PAX4 paired box 4 acts_upstream_of ISO (MGI:2686854|PMID:14729487) MGI PMID:14729487 MGI:2686854 NCBI chr14:8,714,251...8,719,387
Ensembl chr14:8,714,949...8,719,371
JBrowse link
G PAX6 paired box 6 acts_upstream_of_or_within ISO (MGI:5437569|PMID:22764048) RGD
MGI
PMID:22403172 PMID:22764048 MGI:5437569 RGD:8552355
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:3612374|PMID:16418487)
GO_Central
Ensembl
MGI
GO_Central
PMID:16418487 PMID:21873635 GO_REF:0000107 MGI:3612374 NCBI chr25:11,741,863...11,746,885
Ensembl chr25:11,741,863...11,746,885
JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:57,242,563...57,297,300
Ensembl chr 1:57,241,927...57,296,546
JBrowse link
G VHL von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO (MGI:5618205|PMID:25186293) MGI PMID:25186293 MGI:5618205 NCBI chr20:8,206,616...8,211,347
Ensembl chr20:8,206,616...8,211,323
JBrowse link
G ZBED6 zinc finger BED-type containing 6 involved_in ISO (MGI:5511070|PMID:24043816) UniProt PMID:24043816 MGI:5511070 NCBI chr38:461,394...467,894 JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:3703458|PMID:17202186), (MGI:3768695|PMID:17988662) MGI PMID:17202186 PMID:17988662 MGI:3703458 MGI:3768695 NCBI chr24:1,933,176...1,935,875
Ensembl chr24:1,925,013...1,935,874
JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 acts_upstream_of_or_within ISO (MGI:3611530|PMID:16423820) MGI PMID:16423820 MGI:3611530 NCBI chr 6:11,112,233...11,115,776
Ensembl chr 6:11,114,694...11,115,257
JBrowse link
G GDF11 growth differentiation factor 11 acts_upstream_of_or_within ISO (MGI:3512831|PMID:15548585) MGI PMID:15548585 MGI:3512831 NCBI chr10:142,039...152,537
Ensembl chr10:145,036...148,373
JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:91,773,492...92,060,895
Ensembl chr 1:91,778,481...92,059,792
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16442
    multicellular organismal process 7792
      multicellular organism development 5252
        system development 4797
          endocrine system development 168
            adrenal gland development + 40
            endocrine pancreas development + 55
            parathyroid gland development + 7
            pineal gland development 0
            pituitary gland development + 50
            ring gland development 0
            thyroid gland development + 34
Path 2
Term Annotations click to browse term
  biological_process 16442
    developmental process 6558
      anatomical structure development 6130
        multicellular organism development 5252
          system development 4797
            endocrine system development 168
              adrenal gland development + 40
              endocrine pancreas development + 55
              parathyroid gland development + 7
              pineal gland development 0
              pituitary gland development + 50
              ring gland development 0
              thyroid gland development + 34
paths to the root