Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:endocrine system development
go back to main search page
Accession:GO:0035270 term browser browse the term
Definition:Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.


show annotations for term's descendants           Sort by:
 
endocrine system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3655758|PMID:16951258) MGI PMID:16951258 MGI:3655758 NCBI chr20:20,317,060...20,320,051 JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3576468|PMID:9140068) MGI
Ensembl		 PMID:9140068 GO_REF:0000107 MGI:3576468 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G GHRH growth hormone releasing hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607618|PMID:15985453) MGI
Ensembl		 PMID:15985453 GO_REF:0000107 MGI:3607618 NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240 		JBrowse link
G GHRHR growth hormone releasing hormone receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:51713|PMID:1504465), (MGI:54124|PMID:1270792), (MGI:63703|PMID:1329576) MGI
Ensembl		 PMID:1270792 PMID:1329576 PMID:1504465 GO_REF:0000107 MGI:51713 MGI:54124 MGI:63703 NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200 		JBrowse link
G GSX1 GS homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:79250|PMID:8631293) MGI
Ensembl		 PMID:8631293 GO_REF:0000107 MGI:79250 NCBI chr13:9,082,674...9,085,014
Ensembl chr13:27,427,569...27,428,876 		JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3827091|PMID:18996108) MGI
Ensembl		 PMID:18996108 GO_REF:0000107 MGI:3827091 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G POU1F1 POU class 1 homeobox 1 ISO RGD PMID:16216912 RGD:1601440 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:894559|PMID:9247269) MGI
Ensembl		 PMID:9247269 GO_REF:0000107 MGI:894559 NCBI chr 5:1,687,079...1,739,729
Ensembl chr 5:1,437,567...1,488,829 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (MGI:3689142|PMID:16932809) RGD
MGI		 PMID:16932809 PMID:21815952 MGI:3689142 RGD:8661681 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUOX2 dual oxidase 2 acts_upstream_of_or_within ISO (MGI:3712355|PMID:17440044) MGI PMID:17440044 MGI:3712355 NCBI chr15:24,040,513...24,061,758
Ensembl chr15:42,395,135...42,414,281 		JBrowse link
adrenal chromaffin cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2387977|PMID:12361965) MGI
Ensembl		 PMID:12361965 GO_REF:0000107 MGI:2387977 NCBI chr12:100,536,895...100,539,737
Ensembl chr12:103,932,302...103,932,999 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in ISO (MGI:3772428|PMID:18094025) UniProt PMID:18094025 MGI:3772428 NCBI chr20:20,317,060...20,320,051 JBrowse link
adrenal cortex development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC5 armadillo repeat containing 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5913685|PMID:28911199) MGI
Ensembl		 PMID:28911199 GO_REF:0000107 MGI:5913685 NCBI chr16:23,498,343...23,507,287
Ensembl chr16:31,828,037...31,840,479 		JBrowse link
adrenal cortex formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in ISO (MGI:3790398|PMID:17537799) UniProt PMID:17537799 MGI:3790398 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G WT1 WT1 transcription factor involved_in ISO (MGI:3790398|PMID:17537799) UniProt PMID:17537799 MGI:3790398 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249 		JBrowse link
adrenal gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR2A activin A receptor type 2A ISO RGD PMID:12844345 RGD:728125 NCBI chr2B:11,933,683...12,020,287
Ensembl chr2B:152,253,826...152,288,385 		JBrowse link
G ACVR2B activin A receptor type 2B ISO RGD PMID:12844345 RGD:728125 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063 		JBrowse link
G APOA1 apolipoprotein A1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2180727|PMID:8647961) MGI
Ensembl		 PMID:8647961 GO_REF:0000107 MGI:2180727 NCBI chr11:111,673,539...111,675,428
Ensembl chr11:115,606,136...115,608,122 		JBrowse link
G ARID5B AT-rich interaction domain 5B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2137956|PMID:11483573) MGI
Ensembl		 PMID:11483573 GO_REF:0000107 MGI:2137956 NCBI chr10:58,426,519...58,621,986
Ensembl chr10:60,756,484...60,952,174 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C acts_upstream_of_or_within ISO (MGI:3839493|PMID:19276117) MGI PMID:19276117 MGI:3839493 NCBI chr11:2,908,537...2,911,134 JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 acts_upstream_of_or_within ISO (MGI:2179743|PMID:11694877), (MGI:3606737|PMID:15615595) MGI PMID:11694877 PMID:15615595 MGI:2179743 MGI:3606737 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G CRH corticotropin releasing hormone acts_upstream_of_or_within ISO (MGI:1860037|PMID:10861000) MGI PMID:10861000 MGI:1860037 NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 involved_in ISO (MGI:1267130|PMID:9655498) UniProt PMID:9655498 MGI:1267130 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO RGD PMID:17065412 RGD:4889133 NCBI chr10:99,431,762...99,439,619
Ensembl chr10:102,896,376...102,901,514 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:8097866 RGD:4145970 NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO RGD PMID:10098502 RGD:7829725 NCBI chr2A:38,087,863...38,096,529
Ensembl chr2A:38,851,000...38,859,824 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G FDX1 ferredoxin 1 ISO RGD PMID:8097866 RGD:4145970 NCBI chr11:105,311,613...105,345,414 JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:69334|PMID:7958830) MGI PMID:7958830 MGI:69334 NCBI chr12:22,954,946...23,096,623 JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO (MGI:5493430|PMID:23300479) CACAO PMID:23300479 MGI:5493430 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G INSR insulin receptor involved_in ISO (MGI:5493430|PMID:23300479) CACAO PMID:23300479 MGI:5493430 NCBI chr19:6,393,407...6,578,234
Ensembl chr19:7,260,246...7,414,889 		JBrowse link
G MDK midkine involved_in ISO PMID:11136554 UniProt PMID:11136554 RGD:62414 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254 		JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3689139|PMID:16906226) MGI
Ensembl		 PMID:16906226 GO_REF:0000107 MGI:3689139 NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2159510|PMID:11796523) MGI
Ensembl		 PMID:11796523 GO_REF:0000107 MGI:2159510 NCBI chr  X:22,903,403...22,908,527
Ensembl chr  X:30,459,527...30,464,652 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:74913|PMID:7628695) MGI
Ensembl		 PMID:7628695 GO_REF:0000107 MGI:74913 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269 		JBrowse link
G NR5A1 nuclear receptor subfamily 5 group A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2159510|PMID:11796523)
(MGI:5287526|PMID:21820362)
(MGI:3604914|PMID:16176945)		 MGI
Ensembl		 PMID:11796523 PMID:16176945 PMID:21820362 GO_REF:0000107 MGI:2159510 MGI:3604914 MGI:5287526 NCBI chr 9:95,605,282...95,628,773
Ensembl chr 9:124,122,968...124,149,292 		JBrowse link
G PBX1 PBX homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2683990|PMID:14595835) MGI
Ensembl		 PMID:14595835 GO_REF:0000107 MGI:2683990 NCBI chr 1:139,985,392...140,311,845
Ensembl chr 1:143,778,701...144,104,797 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3820330|PMID:19056881) MGI
Ensembl		 PMID:19056881 GO_REF:0000107 MGI:3820330 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta acts_upstream_of_or_within ISO (MGI:3820330|PMID:19056881) MGI PMID:19056881 MGI:3820330 NCBI chr 5:145,538,330...145,580,312
Ensembl chr 5:151,543,891...151,585,530 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:16140489 RGD:5130728 NCBI chr17:17,618,399...17,620,691
Ensembl chr17:17,835,277...17,837,180 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:31,396,399...31,412,753
Ensembl chr16:50,274,090...50,284,819 		JBrowse link
G SMAD2 SMAD family member 2 ISO RGD PMID:12844345 RGD:728125 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530 		JBrowse link
G SMAD3 SMAD family member 3 ISO RGD PMID:12844345 RGD:728125 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:12844345 RGD:728125 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:53,117,891...53,150,790
Ensembl chr15:72,741,482...72,770,876 		JBrowse link
G THRA thyroid hormone receptor alpha ISO RGD PMID:17496154 RGD:2314319 NCBI chr17:17,196,459...17,226,263 JBrowse link
G TSPO translocator protein ISO RGD PMID:9927316 RGD:2317174 NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930 		JBrowse link
G WNT11 Wnt family member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,239,781...71,263,915
Ensembl chr11:74,540,169...74,560,024 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
G WT1 WT1 transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249 		JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202291|PMID:9463347) MGI
Ensembl		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202291|PMID:9463347) MGI
Ensembl		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916 		JBrowse link
endocrine pancreas development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 ISO RGD PMID:7527053 RGD:2306957 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO RGD PMID:11000281 RGD:2315710 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G CLU clusterin ISO RGD PMID:16411126 RGD:1582421 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468 		JBrowse link
G FOXA2 forkhead box A2 involved_in
acts_upstream_of_or_within		 ISO (PMID:12124776)
(MGI:3530180|PMID:15680365)		 BHF-UCL
MGI		 PMID:12124776 PMID:15680365 MGI:3530180 NCBI chr20:22,519,942...22,524,262 JBrowse link
G GIP gastric inhibitory polypeptide acts_upstream_of_or_within ISO (MGI:4940930|PMID:21270265) MGI PMID:21270265 MGI:4940930 NCBI chr17:8,573,104...8,580,424 JBrowse link
G GIPR gastric inhibitory polypeptide receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4940930|PMID:21270265) MGI
Ensembl		 PMID:21270265 GO_REF:0000107 MGI:4940930 NCBI chr19:42,673,553...42,688,059
Ensembl chr19:51,213,090...51,225,293 		JBrowse link
G HNF1B HNF1 homeobox B involved_in ISO (PMID:16801329) UniProt PMID:16801329 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863 		JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:3807360|PMID:18719127) BHF-UCL PMID:18719127 MGI:3807360 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3619850|PMID:16511571) MGI PMID:16511571 MGI:3619850 NCBI chr20:20,317,060...20,320,051 JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 acts_upstream_of_or_within ISO (MGI:1344214|PMID:10471501) MGI PMID:10471501 MGI:1344214 NCBI chr 7:148,622,701...148,628,532 JBrowse link
G MYT1 myelin transcription factor 1 acts_upstream_of_or_within ISO (MGI:3763794|PMID:17928203) MGI PMID:17928203 MGI:3763794 Ensembl chr20:62,108,924...62,151,936 JBrowse link
G NEUROD1 neuronal differentiation 1 involved_in ISO (MGI:1096974|PMID:9308961), (MGI:1352314|PMID:10639171) BHF-UCL PMID:9308961 PMID:10639171 MGI:1096974 MGI:1352314 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NEUROG3 neurogenin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:66,039,739...66,041,804
Ensembl chr10:68,571,614...68,572,258 		JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1270972|PMID:9584121) MGI
Ensembl		 PMID:9584121 GO_REF:0000107 MGI:1270972 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (MGI:3579924|PMID:15944193) MGI PMID:15944193 MGI:3579924 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G NKX6-2 NK6 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3579924|PMID:15944193) MGI
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 Ensembl chr10:133,682,456...133,683,445 JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3710726|PMID:17400205) MGI
Ensembl		 PMID:17400205 GO_REF:0000107 MGI:3710726 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G ONECUT2 one cut homeobox 2 acts_upstream_of_or_within ISO (MGI:3710726|PMID:17400205) MGI PMID:17400205 MGI:3710726 NCBI chr18:50,826,110...50,882,127 JBrowse link
G PDE3B phosphodiesterase 3B acts_upstream_of_or_within ISO (MGI:3040550|PMID:14736883) MGI PMID:14736883 MGI:3040550 NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (MGI:3771560|PMID:18155690) MGI PMID:18155690 MGI:3771560 NCBI chr13:9,199,572...9,206,202 JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G SOX4 SRY-box transcription factor 4 acts_upstream_of_or_within ISO (MGI:3611650|PMID:16306355) MGI PMID:16306355 MGI:3611650 NCBI chr 6:21,422,846...21,427,779 JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:3815251|PMID:18723011) MGI PMID:18723011 MGI:3815251 NCBI chr17:66,028,737...66,034,122 JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT5A Wnt family member 5A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3043884|PMID:15037319) MGI
Ensembl		 PMID:15037319 GO_REF:0000107 MGI:3043884 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1351379|PMID:10615124) MGI
Ensembl		 PMID:10615124 GO_REF:0000107 MGI:1351379 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
negative regulation of thyroid gland epithelial cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAP1GAP RAP1 GTPase activating protein ISO RGD PMID:17646383 RGD:9835038 NCBI chr 1:20,790,076...20,860,511
Ensembl chr 1:21,754,733...21,824,405 		JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator ISO RGD PMID:23178930 RGD:11567224 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864 		JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTP orthopedia homeobox acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1347696|PMID:10557207) MGI
Ensembl		 PMID:10557207 GO_REF:0000107 MGI:1347696 NCBI chr 5:37,667,070...37,677,802
Ensembl chr 5:38,196,327...38,206,313 		JBrowse link
G POU3F2 POU class 3 homeobox 2 acts_upstream_of_or_within ISO (MGI:77941|PMID:8543156) MGI PMID:8543156 MGI:77941 NCBI chr 6:96,677,651...96,682,145 JBrowse link
pancreatic A cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAX6 paired box 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
pancreatic A cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3701716|PMID:16887115) MGI
Ensembl		 PMID:16887115 GO_REF:0000107 MGI:3701716 NCBI chr18:15,411,764...15,444,402 JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:1351379|PMID:10615124) MGI
Ensembl		 PMID:10615124 GO_REF:0000107 MGI:1351379 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3619850|PMID:16511571) UniProt
MGI		 PMID:16511571 MGI:3619850 NCBI chr20:20,317,060...20,320,051 JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (MGI:3579924|PMID:15944193) MGI PMID:15944193 MGI:3579924 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G NKX6-2 NK6 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3579924|PMID:15944193) MGI
Ensembl		 PMID:15944193 GO_REF:0000107 MGI:3579924 Ensembl chr10:133,682,456...133,683,445 JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859126|PMID:10825208) MGI
Ensembl		 PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:20592023 RGD:8552352 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5618205|PMID:25186293) Ensembl
MGI		 PMID:25186293 GO_REF:0000107 MGI:5618205 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234 		JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 acts_upstream_of_or_within ISO (MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:3768695 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3703458|PMID:17202186)
(MGI:3768695|PMID:17988662)		 MGI
Ensembl		 PMID:17202186 PMID:17988662 GO_REF:0000107 MGI:3703458 MGI:3768695 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859126|PMID:10825208) MGI
Ensembl		 PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 acts_upstream_of_or_within ISO (MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:3768695 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3768695|PMID:17988662) MGI
Ensembl		 PMID:17988662 GO_REF:0000107 MGI:3768695 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
parathyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRKL CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3614586|PMID:16399080) MGI
Ensembl		 PMID:16399080 GO_REF:0000107 MGI:3614586 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858 		JBrowse link
G GATA3 GATA binding protein 3 acts_upstream_of_or_within ISO (MGI:4460059|PMID:20484821) MGI PMID:20484821 MGI:4460059 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272 		JBrowse link
G GCM2 glial cells missing transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5780847|PMID:19968565) MGI
Ensembl		 PMID:19968565 GO_REF:0000107 MGI:5780847 NCBI chr 6:10,712,428...10,722,056
Ensembl chr 6:10,990,928...10,999,554 		JBrowse link
G HOXA3 homeobox A3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2149273|PMID:11476574) MGI
Ensembl		 PMID:11476574 GO_REF:0000107 MGI:2149273 NCBI chr 7:27,750,642...27,767,125
Ensembl chr 7:27,350,491...27,371,169 		JBrowse link
G PAX1 paired box 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2149273|PMID:11476574) MGI
Ensembl		 PMID:11476574 GO_REF:0000107 MGI:2149273 NCBI chr20:21,663,155...21,676,880
Ensembl chr20:21,623,771...21,632,608 		JBrowse link
G TBX1 T-box transcription factor 1 involved_in ISO (PMID:14585638) UniProt PMID:14585638 NCBI chr22:2,521,080...2,541,267 JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3703113|PMID:17078885) Ensembl
MGI		 PMID:17078885 GO_REF:0000107 MGI:3703113 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748 		JBrowse link
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:18160680 RGD:2325274 NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749 		JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 ISO RGD PMID:17180597 RGD:2306413 NCBI chr15:36,925,443...37,038,288
Ensembl chr15:55,237,101...55,557,168 		JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 ISO RGD PMID:17180597 RGD:2306413 NCBI chr15:79,603,893...79,640,866
Ensembl chr15:98,891,770...98,928,396 		JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1306869|PMID:9806931) MGI
Ensembl		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709795|PMID:17359964) MGI
Ensembl		 PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912 		JBrowse link
G CDH1 cadherin 1 ISO RGD PMID:17373711 RGD:2289637 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3611103|PMID:16141355) Ensembl
MGI		 PMID:16141355 GO_REF:0000107 MGI:3611103 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO RGD PMID:8946059 RGD:2313681 NCBI chr11:123,272,111...123,400,413
Ensembl chr11:127,174,721...127,288,673 		JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3688470|PMID:11062007) MGI
Ensembl		 PMID:11062007 GO_REF:0000107 MGI:3688470 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G GATA2 GATA binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3625416|PMID:16543408) Ensembl
MGI		 PMID:16543408 GO_REF:0000107 MGI:3625416 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035 		JBrowse link
G GLI1 GLI family zinc finger 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1354188|PMID:10725236) MGI
Ensembl
InterPro		 PMID:10725236 GO_REF:0000002 GO_REF:0000107 MGI:1354188 NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473 		JBrowse link
G GLI2 GLI family zinc finger 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1354188|PMID:10725236) MGI
Ensembl		 PMID:10725236 GO_REF:0000107 MGI:1354188 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442 		JBrowse link
G HES1 hes family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3664138|PMID:17015435), (MGI:3712393|PMID:17426285)
(MGI:3712393|PMID:17426285)		 MGI
Ensembl		 PMID:17015435 PMID:17426285 GO_REF:0000107 MGI:3664138 MGI:3712393 NCBI chr 3:191,432,513...191,435,387
Ensembl chr 3:201,749,044...201,754,257 		JBrowse link
G HESX1 HESX homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
ISS
IEA		 (MGI:3821506|PMID:18775421)
(MGI:3821905|PMID:19093031)
(MGI:1206234|PMID:9620767), (MGI:2154557|PMID:11731482)
(MGI:4440397|PMID:20181723)		 MGI
UniProt
Ensembl		 PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 GO_REF:0000024 GO_REF:0000107 MGI:1206234 MGI:2154557 MGI:3821506 MGI:3821905 MGI:4440397 NCBI chr 3:57,131,419...57,161,205
Ensembl chr 3:58,341,965...58,370,347 		JBrowse link
G HMGA2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO (MGI:54708|PMID:504232) MGI PMID:504232 MGI:54708 NCBI chr12:22,954,946...23,096,623 JBrowse link
G INHBB inhibin subunit beta B ISO RGD PMID:18160680 RGD:2325274 NCBI chr2B:7,278,944...7,284,632 JBrowse link
G ISL1 ISL LIM homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1306869|PMID:9806931) MGI
Ensembl		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674 		JBrowse link
G KDM1A lysine demethylase 1A acts_upstream_of_or_within ISO (MGI:3710033|PMID:17392792) MGI PMID:17392792 MGI:3710033 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692 		JBrowse link
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3771226|PMID:18037398) MGI
Ensembl		 PMID:18037398 GO_REF:0000107 MGI:3771226 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366 		JBrowse link
G MSX1 msh homeobox 1 ISO RGD PMID:16451220 RGD:5132608 Ensembl chr 4:4,935,600...4,939,079 JBrowse link
G NOG noggin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709795|PMID:17359964) MGI
Ensembl		 PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092 		JBrowse link
G PAX6 paired box 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1350715|PMID:10588713) MGI
Ensembl		 PMID:10588713 GO_REF:0000107 MGI:1350715 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:15208361 RGD:2308902 NCBI chr 5:18,917,488...18,960,102
Ensembl chr 5:19,064,004...19,106,486 		JBrowse link
G PITX1 paired like homeodomain 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1332284|PMID:10049363) MGI
Ensembl		 PMID:10049363 GO_REF:0000107 MGI:1332284 NCBI chr 5:130,422,920...130,429,828
Ensembl chr 5:136,565,285...136,570,350 		JBrowse link
G PITX2 paired like homeodomain 2 acts_upstream_of_or_within ISO (MGI:1345532|PMID:10499586)
(MGI:1344731|PMID:10498698)		 MGI PMID:10498698 PMID:10499586 MGI:1344731 MGI:1345532 NCBI chr 4:103,112,624...103,137,356 JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:3625414|PMID:16556738) MGI PMID:16556738 MGI:3625414 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO (MGI:3664138|PMID:17015435) MGI PMID:17015435 MGI:3664138 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:31,396,399...31,412,753
Ensembl chr16:50,274,090...50,284,819 		JBrowse link
G SIX3 SIX homeobox 3 acts_upstream_of_or_within
involved_in		 ISO (MGI:3821506|PMID:18775421) MGI
UniProt		 PMID:18775421 MGI:3821506 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G SOX2 SRY-box transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:178,744,881...178,747,392
Ensembl chr 3:186,922,705...186,923,662 		JBrowse link
G SOX3 SRY-box transcription factor 3 involved_in ISO (MGI:3033563|PMID:14981518) UniProt PMID:14981518 MGI:3033563 NCBI chr  X:129,654,296...129,656,446 JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO RGD PMID:8770891 RGD:4892048 NCBI chr 5:6,953,795...6,996,010
Ensembl chr 5:6,629,093...6,664,264 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:3763872|PMID:17919533) MGI PMID:17919533 MGI:3763872 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281 		JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:80537|PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366 		JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr11:13,436,580...13,547,135
Ensembl chr11:13,163,028...13,240,376 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,391,310...68,509,813
Ensembl chr 4:75,018,898...75,066,726 		JBrowse link
G RHEB Ras homolog, mTORC1 binding involved_in ISO (PMID:19258434) CACAO PMID:19258434 NCBI chr 7:143,054,747...143,108,011 JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:55682|PMID:6194978), (MGI:63474|PMID:6116352) MGI
Ensembl		 PMID:6116352 PMID:6194978 GO_REF:0000107 MGI:55682 MGI:63474 NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:3664138|PMID:17015435) MGI PMID:17015435 MGI:3664138 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:80537|PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366 		JBrowse link
G POU1F1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO (MGI:55682|PMID:6194978), (MGI:80583|PMID:1334535) MGI PMID:1334535 PMID:6194978 MGI:55682 MGI:80583 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168 		JBrowse link
G WNT4 Wnt family member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3777488|PMID:18351662) MGI
Ensembl		 PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
thyroid gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:3832113|PMID:18952847) MGI PMID:18952847 MGI:3832113 NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO (MGI:1316794|PMID:12114718) MGI PMID:12114718 MGI:1316794 NCBI chr 6:84,962,974...84,972,638
Ensembl chr 6:88,236,206...88,247,300 		JBrowse link
G DUOX2 dual oxidase 2 acts_upstream_of_or_within ISO (MGI:3712355|PMID:17440044) MGI PMID:17440044 MGI:3712355 NCBI chr15:24,040,513...24,061,758
Ensembl chr15:42,395,135...42,414,281 		JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545 		JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:139,815,336...139,879,600
Ensembl chr 4:151,476,356...151,536,497 		JBrowse link
G FGF10 fibroblast growth factor 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3688470|PMID:11062007) MGI
Ensembl		 PMID:11062007 GO_REF:0000107 MGI:3688470 NCBI chr 5:65,979,443...66,069,314
Ensembl chr 5:71,028,187...71,111,706 		JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3848569|PMID:19389367) MGI
Ensembl		 PMID:19389367 GO_REF:0000107 MGI:3848569 NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916 		JBrowse link
G FOXE1 forkhead box E1 involved_in
acts_upstream_of_or_within		 ISO (PMID:15494458)
(MGI:1276273|PMID:9697704)
(PMID:9697705)		 UniProt
MGI		 PMID:9697704 PMID:9697705 PMID:15494458 MGI:1276273 NCBI chr 9:68,943,747...68,947,226 JBrowse link
G HESX1 HESX homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3821506|PMID:18775421) MGI
Ensembl		 PMID:18775421 GO_REF:0000107 MGI:3821506 NCBI chr 3:57,131,419...57,161,205
Ensembl chr 3:58,341,965...58,370,347 		JBrowse link
G HHEX hematopoietically expressed homeobox acts_upstream_of_or_within ISO (MGI:1855906|PMID:10804184), (MGI:3522522|PMID:15581879) MGI PMID:10804184 PMID:15581879 MGI:1855906 MGI:3522522 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992 		JBrowse link
G HOXA3 homeobox A3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1201272|PMID:9520319), (MGI:74186|PMID:7635047)
(MGI:1197395|PMID:9524238)		 MGI
Ensembl		 PMID:7635047 PMID:9520319 PMID:9524238 GO_REF:0000107 MGI:1197395 MGI:1201272 MGI:74186 NCBI chr 7:27,750,642...27,767,125
Ensembl chr 7:27,350,491...27,371,169 		JBrowse link
G HOXA5 homeobox A5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2667733|PMID:12815622) MGI
Ensembl		 PMID:12815622 GO_REF:0000107 MGI:2667733 NCBI chr 7:27,786,040...27,789,339
Ensembl chr 7:27,385,175...27,388,990 		JBrowse link
G HOXB3 homeobox B3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1201272|PMID:9520319) MGI
Ensembl		 PMID:9520319 GO_REF:0000107 MGI:1201272 NCBI chr17:8,946,441...8,987,876
Ensembl chr17:9,147,784...9,171,021 		JBrowse link
G HOXD3 homeobox D3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1201272|PMID:9520319) MGI
Ensembl		 PMID:9520319 GO_REF:0000107 MGI:1201272 NCBI chr2B:63,432,720...63,452,816
Ensembl chr2B:181,141,538...181,161,604 		JBrowse link
G LOC100977025 dual specificity mitogen-activated protein kinase kinase 2 acts_upstream_of_or_within ISO (MGI:3832113|PMID:18952847) MGI PMID:18952847 MGI:3832113 NCBI chr19:3,114,445...3,148,619
Ensembl chr19:4,064,626...4,097,933 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 acts_upstream_of_or_within ISO (MGI:3832113|PMID:18952847) MGI PMID:18952847 MGI:3832113 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3832113|PMID:18952847) MGI
Ensembl		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3832113|PMID:18952847) MGI
Ensembl		 PMID:18952847 GO_REF:0000107 MGI:3832113 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G NKX2-1 NK2 homeobox 1 involved_in ISO (PMID:11854319)
(PMID:15494458)		 UniProt PMID:11854319 PMID:15494458 NCBI chr14:17,224,870...17,273,252
Ensembl chr14:35,404,127...35,626,722 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514 		JBrowse link
G PAX8 paired box 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2156109|PMID:11773436)
(PMID:1723950)
(MGI:1203285|PMID:9590297)		 MGI
Ensembl
UniProt		 PMID:1723950 PMID:9590297 PMID:11773436 GO_REF:0000107 MGI:1203285 MGI:2156109 NCBI chr2A:88,845,877...88,905,266
Ensembl chr2A:114,162,110...114,222,865 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3832113|PMID:18952847) MGI
Ensembl		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3702792|PMID:16968815) MGI
Ensembl		 PMID:16968815 GO_REF:0000107 MGI:3702792 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SIX1 SIX homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3624596|PMID:16530750) MGI
Ensembl		 PMID:16530750 GO_REF:0000107 MGI:3624596 NCBI chr14:41,250,512...41,256,567
Ensembl chr14:59,515,324...59,527,494 		JBrowse link
G SIX3 SIX homeobox 3 acts_upstream_of_or_within ISO (MGI:3821506|PMID:18775421) MGI PMID:18775421 MGI:3821506 NCBI chr2A:45,038,634...45,072,867 JBrowse link
G SMAD3 SMAD family member 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3618021|PMID:15183723) MGI
Ensembl		 PMID:15183723 GO_REF:0000107 MGI:3618021 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
G SRF serum response factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3832113|PMID:18952847) MGI
Ensembl		 PMID:18952847 GO_REF:0000107 MGI:3832113 NCBI chr 6:42,763,099...42,773,332
Ensembl chr 6:44,057,192...44,066,768 		JBrowse link
G TBX1 T-box transcription factor 1 acts_upstream_of_or_within ISO (MGI:3848569|PMID:19389367)
(MGI:3050165|PMID:15190012), (MGI:3697808|PMID:17164259)		 MGI PMID:15190012 PMID:17164259 PMID:19389367 MGI:3050165 MGI:3697808 MGI:3848569 NCBI chr22:2,521,080...2,541,267 JBrowse link
G TG thyroglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:129,519,431...129,789,699
Ensembl chr 8:132,495,516...132,764,918 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO RGD PMID:18554691 RGD:2302084 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
G THRA thyroid hormone receptor alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2156109|PMID:11773436) MGI
Ensembl		 PMID:11773436 GO_REF:0000107 MGI:2156109 NCBI chr17:17,196,459...17,226,263 JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202291|PMID:9463347) MGI
Ensembl		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) MGI PMID:9463347 MGI:1202291 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942 		JBrowse link
G FGF8 fibroblast growth factor 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1202291|PMID:9463347) MGI
Ensembl		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr10:98,372,251...98,378,811
Ensembl chr10:101,844,792...101,853,916 		JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3625416|PMID:16543408) MGI
Ensembl		 PMID:16543408 GO_REF:0000107 MGI:3625416 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035 		JBrowse link
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:80537|PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 MGI:80537 NCBI chr 9:107,271,131...107,280,001
Ensembl chr 9:136,252,880...136,260,366 		JBrowse link
G WNT4 Wnt family member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3777488|PMID:18351662) MGI
Ensembl		 PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649 		JBrowse link
G CDH2 cadherin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325 		JBrowse link
G CDK6 cyclin dependent kinase 6 involved_in ISO (PMID:20668294) UniProt PMID:20668294 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G DLL1 delta like canonical Notch ligand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA InterPro GO_REF:0000002 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
G INSM1 INSM transcriptional repressor 1 acts_upstream_of_or_within ISO (MGI:3655758|PMID:16951258) MGI PMID:16951258 MGI:3655758 NCBI chr20:20,317,060...20,320,051 JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3761395|PMID:17456846)
(MGI:3703458|PMID:17202186)		 MGI
Ensembl		 PMID:17202186 PMID:17456846 GO_REF:0000107 MGI:3703458 MGI:3761395 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4365695|PMID:19635472) UniProt PMID:19635472 MGI:4365695 NCBI chr16:1,394,447...1,463,735 JBrowse link
G SIDT2 SID1 transmembrane family member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5529865|PMID:23776622) MGI
Ensembl		 PMID:23776622 GO_REF:0000107 MGI:5529865 NCBI chr11:112,012,734...112,031,403
Ensembl chr11:115,946,725...115,963,408 		JBrowse link
G SMO smoothened, frizzled class receptor acts_upstream_of_or_within ISO (MGI:4833770|PMID:20185815) MGI PMID:20185815 MGI:4833770 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048 		JBrowse link
G WNT5A Wnt family member 5A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3663526|PMID:16246260) MGI
Ensembl		 PMID:16246260 GO_REF:0000107 MGI:3663526 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051 		JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3701716|PMID:16887115) MGI
Ensembl		 PMID:16887115 GO_REF:0000107 MGI:3701716 NCBI chr18:15,411,764...15,444,402 JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in
acts_upstream_of_or_within		 ISO (MGI:3619850|PMID:16511571) UniProt
MGI		 PMID:16511571 MGI:3619850 NCBI chr20:20,317,060...20,320,051 JBrowse link
G MEN1 menin 1 ISO RGD PMID:24157940 RGD:9589069 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164 		JBrowse link
G NKX2-2 NK2 homeobox 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:2686854|PMID:14729487) MGI
Ensembl		 PMID:14729487 GO_REF:0000107 MGI:2686854 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
G NKX6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (MGI:3579924|PMID:15944193) MGI PMID:15944193 MGI:3579924 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1859126|PMID:10825208) MGI
Ensembl		 PMID:10825208 GO_REF:0000107 MGI:1859126 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062 		JBrowse link
G PAX4 paired box 4 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:2686854|PMID:14729487) MGI
Ensembl		 PMID:14729487 GO_REF:0000107 MGI:2686854 NCBI chr 7:119,605,924...119,613,579
Ensembl chr 7:132,260,859...132,268,516 		JBrowse link
G PAX6 paired box 6 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:5437569|PMID:22764048) RGD
Ensembl
MGI		 PMID:22403172 PMID:22764048 GO_REF:0000107 MGI:5437569 RGD:8552355 NCBI chr11:31,753,190...31,782,225
Ensembl chr11:31,641,813...31,664,474 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within		 ISO PMID:21108535
(MGI:3612374|PMID:16418487)
(PMID:12124776), (PMID:24567802)		 BHF-UCL
MGI
CACAO		 PMID:12124776 PMID:16418487 PMID:21108535 PMID:24567802 MGI:3612374 RGD:8553608 NCBI chr13:9,199,572...9,206,202 JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5618205|PMID:25186293) Ensembl
MGI		 PMID:25186293 GO_REF:0000107 MGI:5618205 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234 		JBrowse link
G ZBED6 zinc finger BED-type containing 6 involved_in ISO (MGI:5511070|PMID:24043816) UniProt PMID:24043816 MGI:5511070 NCBI chr 1:179,400,520...179,405,501
Ensembl chr 1:183,691,160...183,694,099 		JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NKX2-2 NK2 homeobox 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3703458|PMID:17202186), (MGI:3768695|PMID:17988662) MGI
Ensembl		 PMID:17202186 PMID:17988662 GO_REF:0000107 MGI:3703458 MGI:3768695 NCBI chr20:21,468,872...21,480,627
Ensembl chr20:21,429,401...21,432,492 		JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BHLHA15 basic helix-loop-helix family member a15 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3611530|PMID:16423820) MGI
Ensembl		 PMID:16423820 GO_REF:0000107 MGI:3611530 NCBI chr 7:6,306,929...6,311,026
Ensembl chr 7:103,677,022...103,677,593 		JBrowse link
G GDF11 growth differentiation factor 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3512831|PMID:15548585) MGI
Ensembl		 PMID:15548585 GO_REF:0000107 MGI:3512831 NCBI chr12:33,154,530...33,168,427
Ensembl chr12:33,879,180...33,893,252 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15327
    multicellular organismal process 7041
      multicellular organism development 4942
        system development 4511
          endocrine system development 157
            adrenal gland development + 38
            endocrine pancreas development + 51
            parathyroid gland development + 7
            pineal gland development 0
            pituitary gland development + 46
            ring gland development 0
            thyroid gland development + 32
Path 2
Term Annotations click to browse term
  biological_process 15327
    developmental process 6162
      anatomical structure development 5753
        multicellular organism development 4942
          system development 4511
            endocrine system development 157
              adrenal gland development + 38
              endocrine pancreas development + 51
              parathyroid gland development + 7
              pineal gland development 0
              pituitary gland development + 46
              ring gland development 0
              thyroid gland development + 32
paths to the root