ONTOLOGY REPORT - ANNOTATIONS
Term: ectopic germ cell programmed cell death
Accession: GO:0035234
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Definition: Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.
Synonyms: exact_synonym: programmed cell death of ectopic germ cells; programmed cell death, ectopic germ cells
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Bax
BCL2 associated X, apoptosis regulator
acts_upstream_of_or_within
ISO
MGI:1857429|MGI:96677|MGI:96974 (MGI:2680318|PMID:14660547), (MGI:3691300|PMID:17107997) MGI:1857429 (MGI:1329774|PMID:9988273)
RGD
PMID:9988273 PMID:14660547 PMID:17107997
MGI:1329774 MGI:2680318 MGI:3691300
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2l1
Bcl2-like 1
acts_upstream_of
ISO
MGI:2176699 (MGI:1860555|PMID:10894153)
RGD
PMID:10894153
MGI:1860555
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Casp2
caspase 2
acts_upstream_of_or_within
ISO
MGI:107700 (MGI:3691999|PMID:11536012)
RGD
PMID:11536012
MGI:3691999
NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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Casp4
caspase 4
acts_upstream_of_or_within
ISO
MGI:2159366|MGI:97295 (MGI:3691999|PMID:11536012)
RGD
PMID:11536012
MGI:3691999
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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Ddb1
damage-specific DNA binding protein 1
acts_upstream_of involved_in
ISO IEA
MGI:3698413 (MGI:5545663|PMID:24357321) GO_REF:0000107
RGD Ensembl
PMID:24357321
GO_REF:0000107 MGI:5545663
NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676
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Il1a
interleukin 1 alpha
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:96543 (MGI:3691999|PMID:11536012)
Ensembl RGD
PMID:11536012
GO_REF:0000107 MGI:3691999
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
acts_upstream_of_or_within
ISO
MGI:96542 (MGI:3691999|PMID:11536012)
RGD
PMID:11536012
MGI:3691999
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Insl6
insulin-like 6
acts_upstream_of
ISO
MGI:4431170 (MGI:4430687|PMID:19520787)
RGD
PMID:19520787
MGI:4430687
NCBI chr 1:227,069,958...227,073,493
Ensembl chr 1:227,069,958...227,073,493
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Kit
KIT proto-oncogene receptor tyrosine kinase
acts_upstream_of_or_within
ISO
MGI:99702 (MGI:2680318|PMID:14660547) MGI:1856232 (MGI:3797995|PMID:18308723)
RGD
PMID:14660547 PMID:18308723
MGI:2680318 MGI:3797995
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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Kitlg
KIT ligand
acts_upstream_of_or_within
ISO
MGI:1856161 (MGI:3691300|PMID:17107997)
RGD
PMID:17107997
MGI:3691300
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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Mael
maelstrom spermatogenic transposon silencer
acts_upstream_of
ISO
MGI:3795667 (MGI:3813746|PMID:18694567)
RGD
PMID:18694567
MGI:3813746
NCBI chr13:78,457,073...78,496,657
Ensembl chr13:78,457,073...78,496,657
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Prkdc
protein kinase, DNA-activated, catalytic subunit
acts_upstream_of_or_within
ISO
MGI:2667593 (MGI:3700621|PMID:17145779)
RGD
PMID:17145779
MGI:3700621
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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Sod1
superoxide dismutase 1
acts_upstream_of
ISO
MGI:1857873 (MGI:3688805|PMID:16036348)
RGD
PMID:16036348
MGI:3688805
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Syce3
synaptonemal complex central element protein 3
acts_upstream_of
ISO
(MGI:5306741|PMID:20407872)
RGD
PMID:20407872
MGI:5306741
NCBI chr 7:120,456,800...120,482,882
Ensembl chr 7:120,456,800...120,482,973
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Sycp2
synaptonemal complex protein 2
acts_upstream_of
ISO
MGI:3526164 (MGI:3653558|PMID:16717126)
RGD
PMID:16717126
MGI:3653558
NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789
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Tex11
testis expressed 11
acts_upstream_of
ISO
MGI:3526163 (MGI:3774244|PMID:18316482)
RGD
PMID:18316482
MGI:3774244
NCBI chr X:65,932,904...66,196,525
Ensembl chr X:65,932,988...66,196,187
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Topaz1
testis and ovary specific TOPAZ 1
acts_upstream_of_or_within
ISO
MGI:5700076 (MGI:5697228|PMID:26358182)
RGD
PMID:26358182
MGI:5697228
NCBI chr 8:122,358,243...122,412,875
Ensembl chr 8:122,358,243...122,412,875
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Ube2b
ubiquitin-conjugating enzyme E2B
acts_upstream_of
ISO
MGI:2183933 (MGI:2450033|PMID:12556476)
RGD
PMID:12556476
MGI:2450033
NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665
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Unc5c
unc-5 netrin receptor C
acts_upstream_of
ISO
MGI:1857852 (MGI:3775319|PMID:18077458)
RGD
PMID:18077458
MGI:3775319
NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217
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Ybx3
Y box binding protein 3
acts_upstream_of
ISO
MGI:3693011 (MGI:3692516|PMID:16954378)
RGD
PMID:16954378
MGI:3692516
NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
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