Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:ESC/E(Z) complex
go back to main search page
Accession:GO:0035098 term browser browse the term
Definition:A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
Synonyms:exact_synonym: Extra Sex Combs/Enhancer of Zeste complex;   PRC2 complex


show annotations for term's descendants       view all columns           Sort by:
 
ESC/E(Z) complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aebp2 AE binding protein 2 JBrowse link 4 174,799,378 174,863,260 RGD:1624291
G Dnmt3l DNA methyltransferase 3 like JBrowse link 20 11,344,513 11,359,090 RGD:1624291
RGD:1600115
G Eed embryonic ectoderm development JBrowse link 1 154,189,252 154,216,340 RGD:1624291
RGD:13792537
G Epop elongin BC and polycomb repressive complex 2 associated protein JBrowse link 10 85,573,369 85,574,889 RGD:1624291
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit JBrowse link 10 89,104,026 89,139,978 RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1624291
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:1624291
G Jarid2 jumonji and AT-rich interaction domain containing 2 JBrowse link 17 20,183,440 20,365,219 RGD:1624291
G Mtf2 metal response element binding transcription factor 2 JBrowse link 14 2,656,776 2,701,027 RGD:1624291
RGD:13792537
G Phf1 PHD finger protein 1 JBrowse link 20 5,526,926 5,531,940 RGD:1624291
RGD:13792537
G Phf19 PHD finger protein 19 JBrowse link 3 13,957,136 13,978,283 RGD:1624291
RGD:13792537
G Rbbp4 RB binding protein 4, chromatin remodeling factor JBrowse link 5 147,499,880 147,535,240 RGD:1624291
G Rbbp7 RB binding protein 7, chromatin remodeling factor JBrowse link X 33,648,682 33,665,821 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
RGD:1600115
G Suz12 SUZ12 polycomb repressive complex 2 subunit JBrowse link 10 67,325,101 67,371,588 RGD:1624291
RGD:13792537
G Trim37 tripartite motif-containing 37 JBrowse link 10 74,436,165 74,568,636 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19737
    protein-containing complex 5748
      PcG protein complex 49
        ESC/E(Z) complex 16
Path 2
Term Annotations click to browse term
  cellular_component 19737
    cellular anatomical entity 19353
      organelle 12456
        intracellular organelle 11935
          intracellular membrane-bounded organelle 9923
            nucleus 6746
              nuclear lumen 3990
                nucleoplasm 3363
                  histone methyltransferase complex 84
                    ESC/E(Z) complex 16
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.