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ONTOLOGY REPORT - ANNOTATIONS

Term:embryonic heart tube development
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Accession:GO:0035050 term browser browse the term
Definition:The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.


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embryonic heart tube development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISS
ISO		 GO_REF:0000024
(MGI:5909243|PMID:28854362), (MGI:5913613|PMID:28663440)		 UniProt
RGD		 PMID:28663440 PMID:28854362 GO_REF:0000024 MGI:5909243 MGI:5913613 NCBI chr16:24,694,231...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Cdc42 cell division cycle 42 involved_in ISO MGI:1857473|MGI:2687362 (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Chrd chordin involved_in ISO MGI:2157350 (MGI:3721005|PMID:17685487) RGD PMID:17685487 MGI:3721005 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148567 (MGI:3773938|PMID:18231602)		 Ensembl
RGD		 PMID:18231602 GO_REF:0000107 MGI:3773938 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ece1 endothelin converting enzyme 1 involved_in ISO MGI:1857637|MGI:2158947|MGI:2687362 (MGI:6304148|PMID:30735130) RGD PMID:30735130 MGI:6304148 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 involved_in ISO MGI:1857473|MGI:1857637|MGI:2158947|MGI:2687362 (MGI:6100594|PMID:24875861), (MGI:6304148|PMID:30735130), (MGI:6362316|PMID:31219639) RGD PMID:24875861 PMID:30735130 PMID:31219639 MGI:6100594 MGI:6304148 MGI:6362316 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:105923|MGI:1857473|MGI:1857637|MGI:2158947|MGI:2179061|MGI:2687362|MGI:3773699 (MGI:4850213|PMID:20929948), (MGI:6100594|PMID:24875861), (MGI:6304148|PMID:30735130), (MGI:6362316|PMID:31219639) RGD PMID:20929948 PMID:24875861 PMID:30735130 PMID:31219639 MGI:4850213 MGI:6100594 MGI:6304148 MGI:6362316 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2176467|MGI:2686864 (MGI:3629000|PMID:16720879)
PMID:21873635		 RGD PMID:16720879 PMID:21873635 MGI:3629000, RGD:13792537 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Foxc1 forkhead box C1 acts_upstream_of_or_within ISO MGI:1347481 (MGI:3701373|PMID:16678147) RGD PMID:16678147 MGI:3701373 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1347466 (MGI:3701373|PMID:16678147) RGD PMID:16678147 MGI:3701373 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:2179443|MGI:2386265 (MGI:87488|PMID:9136932), (MGI:87489|PMID:9136933) RGD PMID:9136932 PMID:9136933 MGI:87488 MGI:87489 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (MGI:2686766|PMID:14732399) RGD PMID:14732399 MGI:2686766 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445466 (MGI:2686766|PMID:14732399), (MGI:5304955|PMID:22203979) RGD PMID:14732399 PMID:22203979 MGI:2686766 MGI:5304955 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO MGI:2153823 (MGI:1197800|PMID:9500551) RGD PMID:9500551 MGI:1197800 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hhex hematopoietically expressed homeobox acts_upstream_of_or_within ISO MGI:2449914 (MGI:3487182|PMID:15459110) RGD PMID:15459110 MGI:3487182 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Ift122 intraflagellar transport 122 involved_in ISO (MGI:3827087|PMID:19000668) RGD PMID:19000668 MGI:3827087 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:2684189 (MGI:2682174|PMID:14500757) RGD PMID:14500757 MGI:2682174 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO MGI:105923|MGI:1857637|MGI:2158947|MGI:2179061|MGI:2687362 (MGI:6304148|PMID:30735130) RGD PMID:30735130 MGI:6304148 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Nckap1 NCK-associated protein 1 acts_upstream_of_or_within ISO MGI:3578145 (MGI:3701029|PMID:16831833) RGD PMID:16831833 MGI:3701029 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO MGI:1888496 (MGI:3578574|PMID:15843414) RGD PMID:15843414 MGI:3578574 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nkx2-6 NK2 homeobox 6 involved_in ISO (PMID:15649947)
(MGI:3828420|PMID:9545560)		 RGD PMID:9545560 PMID:15649947 MGI:3828420 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO MGI:2158732 (MGI:2155575|PMID:11311163) RGD PMID:11311163 MGI:2155575 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Pcnt pericentrin acts_upstream_of_or_within ISO MGI:4340776 (MGI:5696764|PMID:25220058) RGD PMID:25220058 MGI:5696764 NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710 		JBrowse link
G Plxna4 plexin A4 involved_in ISO MGI:105923|MGI:1857637|MGI:2158947|MGI:2179061|MGI:2687362 (MGI:6304148|PMID:30735130) RGD PMID:30735130 MGI:6304148 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 acts_upstream_of_or_within ISO MGI:4849923 (MGI:4867054|PMID:21302256) RGD PMID:21302256 MGI:4867054 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Sox17 SRY-box transcription factor 17 acts_upstream_of_or_within ISO MGI:103559 (MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:3716256 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Sox18 SRY-box transcription factor 18 acts_upstream_of_or_within ISO MGI:107543 (MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:3716256 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290 		JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of_or_within ISO MGI:3579836|MGI:97350 (MGI:3578574|PMID:15843414) RGD PMID:15843414 MGI:3578574 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:5538565 (MGI:5532232|PMID:23844108) RGD PMID:23844108 MGI:5532232 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tmem94 transmembrane protein 94 acts_upstream_of_or_within ISO MGI:6358488 (MGI:6272053|PMID:30526868) RGD PMID:30526868 MGI:6272053 NCBI chr10:100,991,523...101,027,046
Ensembl chr10:100,991,573...101,027,394 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (MGI:5298450|PMID:21945076) RGD PMID:21945076 MGI:5298450 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
embryonic heart tube elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3579960|PMID:15901664) RGD PMID:15901664 MGI:3579960 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
embryonic heart tube formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO (MGI:1927045|PMID:11076684) RGD PMID:11076684 MGI:1927045 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
embryonic heart tube left/right pattern formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISO (MGI:3054669|PMID:15475956) RGD PMID:15475956 MGI:3054669 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ift122 intraflagellar transport 122 involved_in ISO (MGI:4888042|PMID:21209331) RGD PMID:21209331 MGI:4888042 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Invs inversin acts_upstream_of_or_within ISO MGI:1856915 (MGI:892786|PMID:9192865) RGD PMID:9192865 MGI:892786 NCBI chr 5:62,610,916...62,763,813
Ensembl chr 5:62,610,968...62,763,350 		JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in ISO
ISS
IEA		 (MGI:5551355|PMID:24052814)
GO_REF:0000024
GO_REF:0000107		 RGD
CAFA
Ensembl		 PMID:24052814 GO_REF:0000024 GO_REF:0000107 MGI:5551355 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1927227 (MGI:892786|PMID:9192865)		 Ensembl
RGD		 PMID:9192865 GO_REF:0000107 MGI:892786 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Pifo primary cilia formation acts_upstream_of_or_within ISO MGI:4819764 (MGI:4819432|PMID:20643351) RGD PMID:20643351 MGI:4819432 NCBI chr 2:193,475,785...193,493,092
Ensembl chr 2:193,475,782...193,493,139 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (MGI:3783941|PMID:17234970) RGD PMID:17234970 MGI:3783941 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
embryonic heart tube morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:19506109) RGD PMID:19506109 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4354447|PMID:19609448)		 Ensembl
RGD		 PMID:19609448 GO_REF:0000107 MGI:4354447 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5551355|PMID:24052814)
GO_REF:0000024		 Ensembl
RGD
CAFA		 PMID:24052814 GO_REF:0000024 GO_REF:0000107 MGI:5551355 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:1339460|PMID:10393122) RGD PMID:10393122 MGI:1339460 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:1267127|PMID:9628868)		 UniProt
Ensembl
RGD		 PMID:9628868 GO_REF:0000024 GO_REF:0000107 MGI:1267127 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in ISO (MGI:4946573|PMID:21305474) RGD PMID:21305474 MGI:4946573 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3579960|PMID:15901664) RGD PMID:15901664 MGI:3579960 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tead1 TEA domain transcription factor 1 acts_upstream_of_or_within ISO MGI:103262|MGI:104904 (MGI:3773640|PMID:18332127) RGD PMID:18332127 MGI:3773640 NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369 		JBrowse link
G Tead2 TEA domain transcription factor 2 acts_upstream_of_or_within ISO MGI:101876|MGI:103262 (MGI:3773640|PMID:18332127) RGD PMID:18332127 MGI:3773640 NCBI chr 1:95,702,366...95,719,186
Ensembl chr 1:95,703,005...95,719,186 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO MGI:101876|MGI:104904 (MGI:3773640|PMID:18332127) RGD PMID:18332127 MGI:3773640 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Ahi1 Abelson helper integration site 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:F8W3V6 (MGI:5306539|PMID:21959375)		 UniProt
RGD		 PMID:21959375 GO_REF:0000024 MGI:5306539 NCBI chr 1:15,768,047...15,886,744
Ensembl chr 1:15,762,462...15,891,041 		JBrowse link
G Aplnr apelin receptor involved_in ISO (MGI:5584055|PMID:23603510) RGD PMID:23603510 MGI:5584055 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Arl13b ADP-ribosylation factor like GTPase 13B acts_upstream_of_or_within ISO MGI:3578151 (MGI:5430243|PMID:22554696) RGD PMID:22554696 MGI:5430243 NCBI chr11:150,100...217,103
Ensembl chr11:150,955...217,197 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISO (MGI:6717247|PMID:32179481) RGD PMID:32179481 MGI:6717247 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO (MGI:3821640|PMID:19004860) RGD PMID:19004860 MGI:3821640 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520 		JBrowse link
G Ccdc103 coiled-coil domain containing 103 involved_in ISO (PMID:22581229) RGD PMID:22581229 NCBI chr10:87,846,327...87,849,959
Ensembl chr10:87,846,357...87,849,757 		JBrowse link
G Ccdc39 coiled-coil domain containing 39 involved_in ISO (PMID:22693285) RGD PMID:22693285 NCBI chr 2:116,665,261...116,703,364
Ensembl chr 2:116,665,261...116,703,350 		JBrowse link
G Ccdc40 coiled-coil domain containing 40 involved_in IBA
ISO		 PMID:21873635
(PMID:22693285)		 RGD PMID:22693285 PMID:21873635 RGD:13792537 NCBI chr10:104,486,748...104,527,284
Ensembl chr10:104,486,748...104,527,243 		JBrowse link
G Cfc1 cripto, FRL-1, cryptic family 1 acts_upstream_of_or_within ISO MGI:2179530 (MGI:1346729|PMID:10521397) RGD PMID:10521397 MGI:1346729 NCBI chr 9:36,742,106...36,751,931
Ensembl chr 9:36,739,071...36,751,930 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2176158 (MGI:3574743|PMID:15750185) RGD PMID:15750185 MGI:3574743 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cluap1 clusterin associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5523142 (MGI:5509110|PMID:23742838)		 Ensembl
RGD		 PMID:23742838 GO_REF:0000107 MGI:5509110 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:2661305|PMID:12730124)		 Ensembl
RGD		 PMID:12730124 GO_REF:0000107 MGI:2661305 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dnaaf1 dynein, axonemal, assembly factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19944400), (PMID:19944405)		 Ensembl
RGD		 PMID:19944400 PMID:19944405 GO_REF:0000107 NCBI chr19:47,624,534...47,652,314
Ensembl chr19:47,624,181...47,652,313 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 involved_in ISO UniProtKB:Q60838 (MGI:5439040|PMID:22841628) RGD PMID:22841628 MGI:5439040 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO UniProtKB:P51141 (MGI:5439040|PMID:22841628) RGD PMID:22841628 MGI:5439040 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Eng endoglin involved_in ISO (MGI:1337912|PMID:10348742), (MGI:4368063|PMID:19703439) RGD PMID:10348742 PMID:19703439 MGI:1337912 MGI:4368063 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:1857843 (MGI:1340887|PMID:10411502) RGD PMID:10411502 MGI:1340887 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Foxh1 forkhead box H1 involved_in ISO (MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:3055632 NCBI chr 7:108,387,969...108,391,566
Ensembl chr 7:108,387,969...108,390,049 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:3052615|PMID:15310850) RGD PMID:15310850 MGI:3052615 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (MGI:1201220|PMID:9486664) RGD PMID:9486664 MGI:1201220 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO MGI:2153823 (MGI:1197800|PMID:9500551) RGD PMID:9500551 MGI:1197800 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857639 (MGI:892134|PMID:9171826)		 Ensembl
RGD		 PMID:9171826 GO_REF:0000107 MGI:892134 NCBI chr16:32,917,826...32,919,880
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179429 (MGI:3607736|PMID:14659802)		 Ensembl
RGD		 PMID:14659802 GO_REF:0000107 MGI:3607736 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Ift172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3829198 (MGI:3828200|PMID:18930042)		 Ensembl
RGD		 PMID:18930042 GO_REF:0000107 MGI:3828200 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (MGI:3579954|PMID:15930098) RGD PMID:15930098 MGI:3579954 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980 		JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO MGI:3707373 (MGI:3703110|PMID:17027958) RGD PMID:17027958 MGI:3703110 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:5142377|PMID:11517919) RGD PMID:11517919 MGI:5142377 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Kdm2a lysine demethylase 2A acts_upstream_of_or_within ISO (MGI:5615026|PMID:25463925) RGD PMID:25463925 MGI:5615026 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787 		JBrowse link
G Kif3a kinesin family member 3a acts_upstream_of_or_within ISO MGI:2181727 (MGI:1337724|PMID:10330409) RGD PMID:10330409 MGI:1337724 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Lbx1 ladybird homeobox 1 acts_upstream_of_or_within ISO MGI:2386948 (MGI:3628723|PMID:12522123) RGD PMID:12522123 MGI:3628723 NCBI chr 1:244,083,873...244,085,690
Ensembl chr 1:244,083,873...244,085,690 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:98958 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO
ISS		 (MGI:3830899|PMID:16680724)
GO_REF:0000024		 RGD
UniProt		 PMID:16680724 GO_REF:0000024 MGI:3830899 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:1339460|PMID:10393122) RGD PMID:10393122 MGI:1339460 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:3603514 (MGI:3603078|PMID:16000382) RGD PMID:16000382 MGI:3603078 NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689 		JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:166,345,853...166,471,715
NCBI chr 1:166,491,721...166,530,575
Ensembl chr 1:166,345,859...166,471,719 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1927227 (MGI:3773736|PMID:16510504), (MGI:74918|PMID:7628699), (MGI:892786|PMID:9192865)
GO_REF:0000107		 RGD
Ensembl		 PMID:7628699 PMID:9192865 PMID:16510504 GO_REF:0000107 MGI:3773736 MGI:74918 MGI:892786 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO MGI:106676 (MGI:3624254|PMID:16496285) RGD PMID:16496285 MGI:3624254 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO UniProtKB:O35516 (MGI:2661305|PMID:12730124) RGD PMID:12730124 MGI:2661305 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:2661305|PMID:12730124)		 Ensembl
RGD		 PMID:12730124 GO_REF:0000107 MGI:2661305 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Noto notochord homeobox acts_upstream_of_or_within ISO MGI:3053092 (MGI:5646191|PMID:17884984) RGD PMID:17884984 MGI:5646191 NCBI chr 4:117,961,163...117,965,402
Ensembl chr 4:117,961,163...117,965,402 		JBrowse link
G Nphp3 nephrocystin 3 involved_in ISO (PMID:18371931), (PMID:20007846) RGD PMID:18371931 PMID:20007846 NCBI chr 8:104,621,908...104,662,383
Ensembl chr 8:104,621,864...104,662,383 		JBrowse link
G Ovol2 ovo-like zinc finger 2 acts_upstream_of_or_within ISO MGI:3777011 (MGI:3776202|PMID:17573777) RGD PMID:17573777 MGI:3776202 NCBI chr 3:131,677,388...131,707,844
Ensembl chr 3:131,677,391...131,708,359 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:21719175) RGD PMID:21719175 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (MGI:1347695|PMID:10557208) RGD PMID:10557208 MGI:1347695 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5142377|PMID:11517919)
MGI:1857796 (MGI:1340887|PMID:10411502), (MGI:1346236|PMID:10500184)		 Ensembl
RGD		 PMID:10411502 PMID:10500184 PMID:11517919 GO_REF:0000107 MGI:1340887 MGI:1346236 MGI:5142377 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smad3 SMAD family member 3 acts_upstream_of_or_within ISO MGI:108051 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5142377|PMID:11517919)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:11517919 GO_REF:0000024 GO_REF:0000107 MGI:5142377 NCBI chr 4:58,344,101...58,372,828
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sox17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 ISO (MGI:3716378|PMID:17655922)
MGI:2179440 (MGI:3716256|PMID:17610846)		 RGD PMID:17610846 PMID:17655922 MGI:3716256 MGI:3716378 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:2385465|MGI:2386742 (MGI:3603734|PMID:15929941) RGD PMID:15929941 MGI:3603734 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733 		JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within ISO MGI:2152962 (MGI:1339521|PMID:10385121) RGD PMID:10385121 MGI:1339521 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:3512046 (MGI:3604917|PMID:16155214) RGD PMID:16155214 MGI:3604917 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tbx20 T-box transcription factor 20 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3579849|MGI:3580099 (MGI:3578601|PMID:15843407), (MGI:3579960|PMID:15901664)
PMID:21873635
(MGI:3604925|PMID:15843409)		 RGD PMID:15843407 PMID:15843409 PMID:15901664 PMID:21873635 MGI:3578601 MGI:3579960 MGI:3604925, RGD:13792537 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:2655214|MGI:3769504 (MGI:3769096|PMID:17460765), (MGI:4412356|PMID:18723448) RGD PMID:17460765 PMID:18723448 MGI:3769096 MGI:4412356 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tbx6 T-box transcription factor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO MGI:4343479|MGI:4456438 (MGI:4453264|PMID:20178780) RGD PMID:20178780 MGI:4453264 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in ISO (MGI:2157686|PMID:11440971) RGD PMID:11440971 MGI:2157686 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:1857489 (MGI:3611726|PMID:16291790) RGD PMID:16291790 MGI:3611726 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1298218 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zic3 Zic family member 3 acts_upstream_of_or_within
involved_in		 ISO MGI:2180720|MGI:3043027|MGI:97359 (MGI:3056222|PMID:15384171), (MGI:3624254|PMID:16496285)
(PMID:9354794)		 RGD PMID:9354794 PMID:15384171 PMID:16496285 MGI:3056222 MGI:3624254 NCBI chr  X:136,123,662...136,134,295
Ensembl chr  X:136,124,026...136,134,746 		JBrowse link
negative regulation of heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx2 T-box transcription factor 2 involved_in ISO (MGI:3039059|PMID:15042700) RGD PMID:15042700 MGI:3039059 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529 		JBrowse link
regulation of heart looping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    multicellular organismal process 9178
      multicellular organism development 5165
        tube development 1320
          embryonic heart tube development 95
            embryonic heart tube dorsal/ventral pattern formation 0
            embryonic heart tube elongation 1
            embryonic heart tube left/right pattern formation 7
            embryonic heart tube morphogenesis + 71
            heart rudiment development + 0
Path 2
Term Annotations click to browse term
  biological_process 19746
    developmental process 6931
      anatomical structure development 6386
        multicellular organism development 5165
          system development 4438
            circulatory system development 1338
              heart development 727
                embryonic heart tube development 95
                  embryonic heart tube dorsal/ventral pattern formation 0
                  embryonic heart tube elongation 1
                  embryonic heart tube left/right pattern formation 7
                  embryonic heart tube morphogenesis + 71
                  heart rudiment development + 0
paths to the root