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ONTOLOGY REPORT - ANNOTATIONS

Term:sperm-egg recognition
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Accession:GO:0035036 term browser browse the term
Definition:The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.


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sperm-egg recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD9 CD9 molecule involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G DCST1 DC-STAMP domain containing 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,033,806...155,050,930
Ensembl chr 1:155,033,824...155,050,930 		JBrowse link
G DCST2 DC-STAMP domain containing 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,018,527...155,033,781
Ensembl chr 1:155,018,520...155,033,781 		JBrowse link
G FOLR1 folate receptor alpha involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:72,189,709...72,196,323
Ensembl chr11:72,189,558...72,196,323 		JBrowse link
G FOLR2 folate receptor beta involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:72,216,794...72,221,950
Ensembl chr11:72,216,601...72,221,950 		JBrowse link
G FOLR3 folate receptor gamma involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:72,135,725...72,139,892
Ensembl chr11:72,114,869...72,139,892 		JBrowse link
G FREY1 Frey regulator of sperm-oocyte fusion 1 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:45,906,534...45,907,271
Ensembl chr11:45,906,513...45,907,272 		JBrowse link
G IZUMO1 izumo sperm-oocyte fusion 1 involved_in IEA
IBA
ISS		 InterPro
GO_Central
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr19:48,740,852...48,746,909
Ensembl chr19:48,740,852...48,746,909 		JBrowse link
G IZUMO1R IZUMO1 receptor, JUNO involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:94,304,580...94,308,146
Ensembl chr11:94,304,580...94,308,146 		JBrowse link
G SPACA3 sperm acrosome associated 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15982649) Ensembl
MGI		 PMID:15982649 GO_REF:0000107 NCBI chr17:32,991,847...32,997,877
Ensembl chr17:32,970,376...32,997,877 		JBrowse link
G SPACA4 sperm acrosome associated 4 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr19:48,606,742...48,607,714
Ensembl chr19:48,606,742...48,607,714 		JBrowse link
G SPESP1 sperm equatorial segment protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:68,930,525...68,946,811
Ensembl chr15:68,818,221...68,946,811 		JBrowse link
G SPPL2C signal peptide peptidase like 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr17:45,844,881...45,847,067
Ensembl chr17:45,844,881...45,847,067 		JBrowse link
binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15685642) Ensembl
MGI		 PMID:15685642 GO_REF:0000107 NCBI chr22:50,738,204...50,745,339
Ensembl chr22:50,738,196...50,745,339 		JBrowse link
G ADAM18 ADAM metallopeptidase domain 18 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:39,584,568...39,730,065
Ensembl chr 8:39,584,489...39,730,065 		JBrowse link
G ADAM1A ADAM metallopeptidase domain 1A (pseudogene) acts_upstream_of_or_within ISO (PMID:15194697) MGI PMID:15194697 NCBI chr12:111,899,063...111,901,902
Ensembl chr12:111,899,263...111,901,391 		JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227 		JBrowse link
G ADAM32 ADAM metallopeptidase domain 32 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:39,107,529...39,284,917
Ensembl chr 8:39,106,990...39,284,917 		JBrowse link
G ADAM3A ADAM metallopeptidase domain 3A (pseudogene) acts_upstream_of_or_within ISO (PMID:32529245)
(PMID:15194697)
(PMID:16330764)		 MGI PMID:15194697 PMID:16330764 PMID:32529245 NCBI chr 8:39,451,045...39,522,989
Ensembl chr 8:39,451,045...39,522,852
Ensembl chr 8:39,451,045...39,522,852 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A involved_in IMP (PMID:23355646) CAFA PMID:23355646 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ARSA arylsulfatase A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12080020) Ensembl
MGI		 PMID:12080020 GO_REF:0000107 NCBI chr22:50,622,754...50,628,152
Ensembl chr22:50,622,754...50,628,173 		JBrowse link
G ATP8B3 ATPase phospholipid transporting 8B3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14975727) Ensembl
MGI		 PMID:14975727 GO_REF:0000107 NCBI chr19:1,782,075...1,812,276
Ensembl chr19:1,782,075...1,812,276 		JBrowse link
G B4GALT1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9374408)
(PMID:8089187), (PMID:9374408)		 Ensembl
MGI		 PMID:8089187 PMID:9374408 GO_REF:0000107 NCBI chr 9:33,104,077...33,185,089
Ensembl chr 9:33,104,082...33,167,356 		JBrowse link
G C4BPA complement component 4 binding protein alpha involved_in
acts_upstream_of_or_within		 ISO (MGI:4942258|PMID:11417900)
(PMID:21880732), (PMID:7604284)		 UniProt
MGI		 PMID:7604284 PMID:11417900 PMID:21880732 MGI:4942258 NCBI chr 1:207,104,233...207,144,972
Ensembl chr 1:207,104,233...207,144,972 		JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570 		JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 1:156,308,968...156,338,292
Ensembl chr 1:156,308,968...156,367,873 		JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 2:61,868,085...61,888,671
Ensembl chr 2:61,868,085...61,888,671 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389 		JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A acts_upstream_of_or_within ISO (PMID:21880732) MGI PMID:21880732 NCBI chr 7:56,051,765...56,063,989
Ensembl chr 7:56,051,685...56,063,989 		JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 2:73,234,308...73,253,005
Ensembl chr 2:73,233,420...73,253,021 		JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr21:29,056,326...29,073,648
Ensembl chr21:29,055,805...29,073,797 		JBrowse link
G CLGN calmegin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11784061), (PMID:9177349) Ensembl
MGI		 PMID:9177349 PMID:11784061 GO_REF:0000107 NCBI chr 4:140,388,453...140,427,648
Ensembl chr 4:140,388,453...140,427,661 		JBrowse link
G CRISP1 cysteine rich secretory protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:21865554) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:21865554 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:49,834,257...49,877,096
Ensembl chr 6:49,834,257...49,877,096 		JBrowse link
G FETUB fetuin B involved_in IEA
IBA
ISS		 Ensembl
GO_Central
TreeGrafter
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:186,635,969...186,653,141
Ensembl chr 3:186,635,969...186,653,141 		JBrowse link
G GLIPR1L1 GLIPR1 like 1 acts_upstream_of_or_within ISO (PMID:8260598) MGI PMID:8260598 NCBI chr12:75,334,670...75,370,560
Ensembl chr12:75,334,670...75,370,560 		JBrowse link
G H1-6 H1.6 linker histone, cluster member acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr 6:26,107,412...26,108,135
Ensembl chr 6:26,107,412...26,108,135 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B acts_upstream_of_or_within ISO (PMID:21880732) MGI PMID:21880732 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283 		JBrowse link
G LY6K lymphocyte antigen 6 family member K involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:24501175) GO_Central
MGI		 PMID:24501175 GO_REF:0000033 NCBI chr 8:142,700,111...142,705,127
Ensembl chr 8:142,700,111...142,705,127 		JBrowse link
G PCSK4 proprotein convertase subtilisin/kexin type 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:16371590) Ensembl
MGI
UniProt		 PMID:16371590 GO_REF:0000024 GO_REF:0000107 NCBI chr19:1,481,428...1,490,876
Ensembl chr19:1,481,428...1,490,752 		JBrowse link
G PMIS2 PMIS2 transmembrane protein acts_upstream_of_or_within ISO (PMID:22621904) MGI PMID:22621904 NCBI chr19:35,586,161...35,587,296
Ensembl chr19:35,586,161...35,587,296 		JBrowse link
G PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:48,744,591...48,847,874
Ensembl chr 3:48,744,597...48,847,874 		JBrowse link
G PRSS37 serine protease 37 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:23553430) Ensembl
MGI
UniProt		 PMID:23553430 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:141,836,278...141,841,485
Ensembl chr 7:141,836,300...141,841,487 		JBrowse link
G PRSS55 serine protease 55 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:10,525,532...10,554,166
Ensembl chr 8:10,525,532...10,554,166 		JBrowse link
G SMCP sperm mitochondria associated cysteine rich protein acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr 1:152,878,322...152,885,047
Ensembl chr 1:152,878,322...152,885,047 		JBrowse link
G SPA17 sperm autoantigenic protein 17 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:124,673,904...124,697,518
Ensembl chr11:124,673,844...124,697,518 		JBrowse link
G SPAM1 sperm adhesion molecule 1 involved_in TAS (PMID:8195297) PINC PMID:8195297 NCBI chr 7:123,925,241...123,971,414
Ensembl chr 7:123,925,237...123,971,414 		JBrowse link
G TCP1 t-complex 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703 		JBrowse link
G TEX101 testis expressed 101 involved_in IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:43,388,611...43,418,597
Ensembl chr19:43,401,496...43,418,597 		JBrowse link
G TMPRSS12 transmembrane serine protease 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32529245) Ensembl
MGI		 PMID:32529245 GO_REF:0000107 NCBI chr12:50,842,926...50,887,884
Ensembl chr12:50,842,920...50,887,884 		JBrowse link
G TNP2 transition protein 2 acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr16:11,267,857...11,269,325
Ensembl chr16:11,267,748...11,269,533 		JBrowse link
G UBAP2L ubiquitin associated protein 2 like involved_in IMP (PMID:19945174) UniProt PMID:19945174 NCBI chr 1:154,220,172...154,271,510
Ensembl chr 1:154,220,179...154,271,510 		JBrowse link
G VDAC2 voltage dependent anion channel 2 involved_in IMP (PMID:23355646) CAFA PMID:23355646 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448 		JBrowse link
G ZAN zonadhesin acts_upstream_of_or_within
involved_in		 ISO
NAS		 (PMID:7592795)
(PMID:9126492)		 MGI
UniProt		 PMID:7592795 PMID:9126492 NCBI chr 7:100,733,595...100,797,797
Ensembl chr 7:100,733,595...100,797,797 		JBrowse link
G ZP1 zona pellucida glycoprotein 1 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:60,867,542...60,875,687
Ensembl chr11:60,867,542...60,875,693 		JBrowse link
G ZP2 zona pellucida glycoprotein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
TAS
ISS		 (PMID:11739644)
(PMID:8385033)
(PMID:22472438)		 Ensembl
MGI
GO_Central
PINC
UniProt		 PMID:8385033 PMID:11739644 PMID:22472438 GO_REF:0000033 GO_REF:0000107 NCBI chr16:21,197,450...21,214,510
Ensembl chr16:21,197,450...21,214,510 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in
acts_upstream_of_or_within		 IGI
ISO
IBA
IDA
IMP		 (PMID:9609824)
(PMID:9374408)
(PMID:11739644)
(PMID:19246320), (PMID:19700799)
(PMID:19004505)		 UniProt
MGI
GO_Central		 PMID:9374408 PMID:9609824 PMID:11739644 PMID:19004505 PMID:19246320 More... GO_REF:0000033 NCBI chr 7:76,397,522...76,442,069
Ensembl chr 7:76,397,518...76,442,071 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:237,882,404...237,890,922
Ensembl chr 1:237,877,864...237,890,922 		JBrowse link
G ZPBP zona pellucida binding protein involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:21880732) InterPro
MGI
GO_Central		 PMID:21880732 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:49,840,654...50,093,246
Ensembl chr 7:49,850,421...50,121,329 		JBrowse link
G ZPBP2 zona pellucida binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:21880732) Ensembl
MGI
GO_Central
InterPro		 PMID:21880732 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr17:39,868,202...39,877,896
Ensembl chr17:39,868,202...39,877,896 		JBrowse link
negative regulation of binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASTL astacin like metalloendopeptidase involved_in IEA
ISS		 (PMID:22472438) Ensembl
UniProt		 PMID:22472438 GO_REF:0000107 NCBI chr 2:96,122,818...96,138,564
Ensembl chr 2:96,122,818...96,138,502 		JBrowse link
G OVGP1 oviductal glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19808884) Ensembl
MGI		 PMID:19808884 GO_REF:0000107 NCBI chr 1:111,414,319...111,427,735
Ensembl chr 1:111,414,319...111,427,735 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in IDA (PMID:18667750) UniProt PMID:18667750 NCBI chr 7:76,397,522...76,442,069
Ensembl chr 7:76,397,518...76,442,071 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IDA (PMID:18667750) UniProt PMID:18667750 NCBI chr 1:237,882,404...237,890,922
Ensembl chr 1:237,877,864...237,890,922 		JBrowse link
regulation of binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAEP progestagen associated endometrial protein involved_in IDA (PMID:17192260) UniProt PMID:17192260 NCBI chr 9:135,561,756...135,566,955
Ensembl chr 9:135,561,756...135,566,955 		JBrowse link
G ZAN zonadhesin acts_upstream_of_or_within ISO (PMID:20529856) MGI PMID:20529856 NCBI chr 7:100,733,595...100,797,797
Ensembl chr 7:100,733,595...100,797,797 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    reproductive process 2047
      fertilization 261
        single fertilization 210
          sperm-egg recognition 63
            binding of sperm to zona pellucida + 50
Path 2
Term Annotations click to browse term
  biological_process 19669
    reproductive process 2047
      sexual reproduction 1372
        fertilization 261
          single fertilization 210
            sperm-egg recognition 63
              binding of sperm to zona pellucida + 50
paths to the root