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ONTOLOGY REPORT - ANNOTATIONS

Term:protein folding in endoplasmic reticulum
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Accession:GO:0034975 term browser browse the term
Definition:A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
Synonyms:exact_synonym: oxidative protein folding;   protein folding in ER


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protein folding in endoplasmic reticulum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:23769672)
GO_REF:0000002
GO_REF:0000104		 UniProt
RGD
InterPro		 PMID:23769672 GO_REF:0000002 GO_REF:0000024 GO_REF:0000104 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Emc1 ER membrane protein complex subunit 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888 		JBrowse link
G Emc2 ER membrane protein complex subunit 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:74,587,196...74,624,163
Ensembl chr 7:74,587,175...74,625,189 		JBrowse link
G Emc3 ER membrane protein complex subunit 3 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 4:146,663,065...146,678,976
Ensembl chr 4:146,663,067...146,679,029 		JBrowse link
G Emc4 ER membrane protein complex subunit 4 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 3:99,169,711...99,174,730
Ensembl chr 3:99,169,711...99,174,729 		JBrowse link
G Emc6 ER membrane protein complex subunit 6 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:57,794,072...57,795,671
Ensembl chr10:57,793,685...57,796,217 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000118
GO_REF:0000033		 InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta involved_in ISO
IBA		 (PMID:21091435)
GO_REF:0000033		 RGD
GO_Central		 PMID:21091435 GO_REF:0000033 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO (PMID:21091435) RGD PMID:21091435 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Suco SUN domain containing ossification factor involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr13:74,192,808...74,257,896
Ensembl chr13:74,193,573...74,257,896 		JBrowse link
G Vapa VAMP associated protein A NOT|involved_in ISO (PMID:18713837) RGD PMID:18713837 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      protein folding 234
        protein folding in endoplasmic reticulum 12
          regulation of protein folding in endoplasmic reticulum 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular metabolic process 9901
        cellular biosynthetic process 8027
          macromolecule biosynthetic process 7463
            gene expression 7014
              protein maturation 562
                protein folding 234
                  protein folding in endoplasmic reticulum 12
                    regulation of protein folding in endoplasmic reticulum 0
paths to the root