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ONTOLOGY REPORT - ANNOTATIONS


Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936683:1,224,703...1,326,761
Ensembl chrNW_004936683:1,222,450...1,326,765
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of
IEA
ISO
(PMID:21700773) Ensembl
MGI
PMID:21700773 GO_REF:0000107 NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:4,600,344...4,608,793
Ensembl chrNW_004936588:4,600,344...4,608,787
JBrowse link
G Mcoln2 mucolipin TRP cation channel 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936608:690,253...744,803
Ensembl chrNW_004936608:690,253...744,001
JBrowse link
G Mmgt1 membrane magnesium transporter 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004936513:11,229,354...11,239,152
Ensembl chrNW_004936513:11,229,506...11,239,525
JBrowse link
G Scara5 scavenger receptor class A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936675:763,467...868,021
Ensembl chrNW_004936675:765,378...863,843
JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936569:888,309...895,991
Ensembl chrNW_004936569:887,742...895,977
JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936512:8,590,302...8,622,121
Ensembl chrNW_004936512:8,586,262...8,623,597
JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(PMID:21653899)
UniProt PMID:20682781 PMID:21653899 NCBI chrNW_004939045:1...7,491 JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21700773) InterPro
MGI
TreeGrafter
Ensembl
PMID:21700773 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936506:8,396,593...8,415,069
Ensembl chrNW_004936506:8,396,912...8,416,374
JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc48a1 solute carrier family 48 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:5,672,952...5,680,502
Ensembl chrNW_004936512:5,672,952...5,684,113
JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:1,628,649...1,635,599
Ensembl chrNW_004936569:1,625,374...1,635,694
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:5,838,044...5,916,287
Ensembl chrNW_004936578:5,837,993...5,916,274
JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004936503:5,323,206...5,343,228 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157
JBrowse link
G Slc25a28 solute carrier family 25 member 28 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936636:462,303...472,937
Ensembl chrNW_004936636:462,205...473,359
JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in IEA TreeGrafter
UniProt
Ensembl
GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004936555:6,980,239...7,016,490
Ensembl chrNW_004936555:6,980,194...7,018,134
JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936506:8,396,593...8,415,069
Ensembl chrNW_004936506:8,396,912...8,416,374
JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936520:961,376...1,036,801
Ensembl chrNW_004936520:962,756...1,037,274
JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:16609065) MGI
Ensembl
PMID:16609065 GO_REF:0000107 NCBI chrNW_004936621:3,784,628...3,806,787
Ensembl chrNW_004936621:3,779,745...3,806,851
JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936683:1,224,703...1,326,761
Ensembl chrNW_004936683:1,222,450...1,326,765
JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686
JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:492,024...498,587
Ensembl chrNW_004936769:491,530...498,692
JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chrNW_004936683:2,874,022...2,936,214
Ensembl chrNW_004936683:2,874,042...2,935,040
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21700773) Ensembl
MGI
TreeGrafter
PMID:21700773 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686
JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chrNW_004936558:5,162,471...5,302,488
Ensembl chrNW_004936558:5,233,459...5,301,414
JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Heph hephaestin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936635:1,954,771...2,022,061
Ensembl chrNW_004936635:1,954,947...2,022,101
JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
JBrowse link
G Lcn2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17411
    cellular process 17014
      transmembrane transport 1538
        inorganic ion transmembrane transport 917
          inorganic cation transmembrane transport 823
            iron ion transmembrane transport 25
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 5
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 3
              regulation of iron ion transmembrane transport + 7
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 17411
    localization 5143
      establishment of localization 4494
        transport 4189
          monoatomic ion transport 1222
            monoatomic cation transport 1046
              metal ion transport 894
                transition metal ion transport 110
                  iron ion transport 64
                    iron ion transmembrane transport 25
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 5
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 3
                      regulation of iron ion transmembrane transport + 7
                      siderophore transmembrane transport 0
paths to the root