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ONTOLOGY REPORT - ANNOTATIONS


Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:17192393)
UniProt
RGD
PMID:17192393 GO_REF:0000024 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858
JBrowse link
G Mmgt1 membrane magnesium transporter 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:134,408,463...134,420,798
Ensembl chr  X:134,408,466...134,420,729
JBrowse link
G Scara5 scavenger receptor class A, member 5 involved_in ISO (MGI:3833042|PMID:19154717) RGD PMID:19154717 MGI:3833042 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373
JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in ISO
IEA
(PMID:17293870)
GO_REF:0000107
RGD
Ensembl
PMID:17293870 GO_REF:0000107 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(MGI:5295560|PMID:21653899), (MGI:6392986|PMID:20682781)
RGD PMID:20682781 PMID:21653899 MGI:5295560 MGI:6392986 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000002
MGI:1933533 (MGI:5293184|PMID:21700773)
PMID:21873635
(PMID:12091367)
InterPro
RGD
PMID:12091367 PMID:21700773 PMID:21873635 GO_REF:0000002 MGI:5293184, RGD:13792537 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 involved_in ISS
ISO
GO_REF:0000024
(PMID:33007128)
UniProt
RGD
PMID:33007128 GO_REF:0000024 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 involved_in ISO
ISS
IEA
(PMID:24836561)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:24836561 GO_REF:0000024 GO_REF:0000107 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a28 solute carrier family 25 member 28 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:242,530,877...242,542,140
Ensembl chr 1:242,530,899...242,542,115
JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in IBA
ISO
PMID:21873635
(MGI:3690197|PMID:16511496)
RGD PMID:16511496 PMID:21873635 MGI:3690197, RGD:13792537 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 member 1 involved_in ISO (MGI:3521561|PMID:15514116) RGD PMID:15514116 MGI:3521561 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
iron ion import across cell outer membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Steap1 STEAP family member 1 NOT|acts_upstream_of_or_within ISO (MGI:3807452|PMID:16609065) RGD PMID:16609065 MGI:3807452 NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (MGI:3807452|PMID:16609065) RGD PMID:16609065 MGI:3807452 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:3758911 (MGI:3807452|PMID:16609065), (MGI:3833805|PMID:18955558) RGD PMID:16609065 PMID:18955558 MGI:3807452 MGI:3833805 NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
JBrowse link
G Steap4 STEAP4 metalloreductase acts_upstream_of_or_within ISO (MGI:3807452|PMID:16609065) RGD PMID:16609065 MGI:3807452 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hfe homeostatic iron regulator involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Slc39a8 solute carrier family 39 member 8 involved_in ISO
IDA
(PMID:22898811)
(MGI:6383325|PMID:30015240)
RGD PMID:22898811 PMID:30015240 PMID:22898811 MGI:6383325, RGD:15090842 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (MGI:3807452|PMID:16609065) RGD PMID:16609065 MGI:3807452 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791
JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:33157103)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:33157103 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858
JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116) RGD PMID:15514116 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150
JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha IMP RGD PMID:24174620 RGD:11341686 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1315204 (MGI:5293184|PMID:21700773)
RGD PMID:21700773 PMID:21873635 MGI:5293184, RGD:13792537 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:14752097 RGD:13824992 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
negative regulation of iron ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116) RGD PMID:15514116 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (MGI:6304699|PMID:29061364) RGD PMID:29061364 MGI:6304699 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Slc6a9 solute carrier family 6 member 9 acts_upstream_of ISO (MGI:6450351|PMID:28495915) RGD PMID:28495915 MGI:6450351 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
positive regulation of iron ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a9 solute carrier family 6 member 9 acts_upstream_of ISO (MGI:6450351|PMID:28495915) RGD PMID:28495915 MGI:6450351 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      transmembrane transport 1582
        ion transmembrane transport 1139
          inorganic ion transmembrane transport 873
            inorganic cation transmembrane transport 804
              iron ion transmembrane transport 24
                heme transmembrane transport + 2
                iron import into the mitochondrion 2
                iron ion export across plasma membrane + 2
                iron ion import across cell outer membrane 4
                iron ion import across plasma membrane + 7
                iron-sulfur cluster transmembrane transport + 1
                negative regulation of iron ion transmembrane transport + 4
                positive regulation of iron ion transmembrane transport + 3
                regulation of iron ion transmembrane transport + 7
                siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6447
      establishment of localization 4864
        transport 4700
          ion transport 1640
            cation transport 1263
              metal ion transport 943
                transition metal ion transport 128
                  iron ion transport 81
                    iron ion transmembrane transport 24
                      heme transmembrane transport + 2
                      iron import into the mitochondrion 2
                      iron ion export across plasma membrane + 2
                      iron ion import across cell outer membrane 4
                      iron ion import across plasma membrane + 7
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 3
                      regulation of iron ion transmembrane transport + 7
                      siderophore transmembrane transport 0
paths to the root