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ONTOLOGY REPORT - ANNOTATIONS

Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,186,559...60,313,098
Ensembl chr  X:60,186,814...60,313,064 		JBrowse link
G HAMP hepcidin antimicrobial peptide acts_upstream_of
involved_in		 ISO
IEA		 (PMID:21700773) MGI
Ensembl		 PMID:21700773 GO_REF:0000107 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:71,602,888...71,613,331
Ensembl chr 2:71,602,770...71,613,312 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,711,789...6,799,318
Ensembl chr14:6,711,442...6,794,667 		JBrowse link
G SCARA5 scavenger receptor class A member 5 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:11,615,629...11,747,336 JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in IEA
IBA		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107
G SLC25A28 solute carrier family 25 member 28 involved_in IEA GOC GO_REF:0000108 NCBI chr14:110,795,304...110,805,631
Ensembl chr14:110,795,307...110,805,570 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,639,485...6,687,929
Ensembl chr14:6,639,206...6,687,924 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21700773) Ensembl
GO_Central
InterPro
MGI		 PMID:21700773 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr15:94,140,635...94,161,793
Ensembl chr15:94,141,988...94,167,408 		JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC48A1 solute carrier family 48 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:78,141,220...78,150,584
Ensembl chr 5:78,141,236...78,150,583 		JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:121,246,180...121,254,350
Ensembl chr15:121,246,187...121,254,331 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:121,868,614...121,957,901
Ensembl chr13:121,869,600...121,926,071 		JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chr 1:222,412,485...222,433,224
Ensembl chr 1:222,412,509...222,434,702 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G SLC25A28 solute carrier family 25 member 28 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:110,795,304...110,805,631
Ensembl chr14:110,795,307...110,805,570 		JBrowse link
G SLC25A37 solute carrier family 25 member 37 involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000117 NCBI chr14:7,665,002...7,709,998
Ensembl chr14:7,665,007...7,706,768 		JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC40A1 solute carrier family 40 member 1 involved_in ISO (PMID:15514116), (PMID:30647129) UniProt PMID:15514116 PMID:30647129 NCBI chr15:94,140,635...94,161,793
Ensembl chr15:94,141,988...94,167,408 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC39A8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:118,604,852...118,678,115
Ensembl chr 8:118,605,402...118,678,107 		JBrowse link
G STEAP2 STEAP2 metalloreductase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16609065) Ensembl
MGI		 PMID:16609065 GO_REF:0000107 NCBI chr 9:70,334,785...70,365,687
Ensembl chr 9:70,349,362...70,366,767 		JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,186,559...60,313,098
Ensembl chr  X:60,186,814...60,313,064 		JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISCU iron-sulfur cluster assembly enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,216,103...42,222,570
Ensembl chr14:42,216,111...42,222,711 		JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G HAMP hepcidin antimicrobial peptide acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:21700773) MGI
GO_Central
Ensembl		 PMID:21700773 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944 		JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEPH hephaestin involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:52,314,911...52,397,384
Ensembl chr  X:52,314,935...52,397,380 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18954
    cellular process 18495
      transmembrane transport 1642
        inorganic ion transmembrane transport 951
          inorganic cation transmembrane transport 848
            iron ion transmembrane transport 24
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 5
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 3
              regulation of iron ion transmembrane transport + 7
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 18954
    localization 5408
      establishment of localization 4757
        transport 4442
          monoatomic ion transport 1271
            monoatomic cation transport 1073
              metal ion transport 921
                transition metal ion transport 107
                  iron ion transport 62
                    iron ion transmembrane transport 24
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 5
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 3
                      regulation of iron ion transmembrane transport + 7
                      siderophore transmembrane transport 0
paths to the root