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ONTOLOGY REPORT - ANNOTATIONS


Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624836:5,605,901...5,769,488
Ensembl chrNW_004624836:5,605,831...5,766,275
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of ISO (PMID:21700773) MGI PMID:21700773 NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264
JBrowse link
G LOC101701909 solute carrier family 40 member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624739:7,791,746...7,827,204 JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:18794901) UniProt PMID:18794901 NCBI chrNW_004624828:634,318...643,406
Ensembl chrNW_004624828:634,214...643,633
JBrowse link
G Scara5 scavenger receptor class A member 5 involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chrNW_004624758:22,661,136...22,757,578
Ensembl chrNW_004624758:22,663,129...22,753,776
JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624823:6,612,452...6,625,047
Ensembl chrNW_004624823:6,612,452...6,625,300
JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624816:1,345,020...1,389,615
Ensembl chrNW_004624816:1,345,006...1,384,299
JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(PMID:21653899)
UniProt PMID:20682781 PMID:21653899 NCBI chrNW_004624758:17,911,889...17,954,870
Ensembl chrNW_004624758:17,912,827...17,953,294
JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21700773) Ensembl
TreeGrafter
MGI
InterPro
PMID:21700773 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624899:685,166...701,725
Ensembl chrNW_004624899:685,097...702,440
JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc48a1 solute carrier family 48 member 1 involved_in ISO (PMID:31571584) MGI PMID:31571584 NCBI chrNW_004624816:4,476,502...4,496,641
Ensembl chrNW_004624816:4,476,491...4,485,030
JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:5,797,897...5,805,055
Ensembl chrNW_004624823:5,797,943...5,808,448
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:72,529,299...72,621,108
Ensembl chrNW_004624730:72,534,329...72,623,263
JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004624736:4,027,054...4,047,881
Ensembl chrNW_004624736:4,027,354...4,047,854
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705
JBrowse link
G Slc25a28 solute carrier family 25 member 28 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624737:11,314,907...11,324,823
Ensembl chrNW_004624737:11,311,772...11,324,821
JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in IEA Ensembl
TreeGrafter
UniProt
GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chrNW_004624758:18,753,465...18,792,025
Ensembl chrNW_004624758:18,753,336...18,792,088
JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624899:685,166...701,725
Ensembl chrNW_004624899:685,097...702,440
JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO PMID:22898811
(PMID:30015240)
(PMID:22898811)
UniProt PMID:22898811 PMID:30015240 RGD:15090842 NCBI chrNW_004624830:5,514,595...5,573,250
Ensembl chrNW_004624830:5,514,780...5,574,894
JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004624809:2,989,360...3,016,283
Ensembl chrNW_004624809:2,993,366...3,016,233
JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624836:5,605,901...5,769,488
Ensembl chrNW_004624836:5,605,831...5,766,275
JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116), (PMID:29237594) BHF-UCL PMID:15514116 PMID:29237594 NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264
JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chrNW_004624747:11,808,789...11,815,269
Ensembl chrNW_004624747:11,808,640...11,816,400
JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chrNW_004624836:2,804,349...3,058,125
Ensembl chrNW_004624836:2,808,681...2,993,452
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21700773) MGI
TreeGrafter
PMID:21700773 GO_REF:0000118 NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264
JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chrNW_004624747:15,940,614...16,118,051
Ensembl chrNW_004624747:16,003,969...16,113,165
JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Heph hephaestin involved_in ISO (PMID:30647129) UniProt PMID:30647129 NCBI chrNW_004624898:1,031,859...1,122,391
Ensembl chrNW_004624898:1,028,882...1,122,461
JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17660
    cellular process 17238
      transmembrane transport 1538
        inorganic ion transmembrane transport 879
          inorganic cation transmembrane transport 788
            iron ion transmembrane transport 23
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 4
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 2
              regulation of iron ion transmembrane transport + 6
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 17660
    localization 5199
      establishment of localization 4570
        transport 4246
          monoatomic ion transport 1211
            monoatomic cation transport 1027
              metal ion transport 891
                transition metal ion transport 107
                  iron ion transport 65
                    iron ion transmembrane transport 23
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 4
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 2
                      regulation of iron ion transmembrane transport + 6
                      siderophore transmembrane transport 0
paths to the root