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ONTOLOGY REPORT - ANNOTATIONS


Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874



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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B member 7 involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000119 NCBI chr  X:103,324,171...103,457,452
Ensembl chr  X:103,324,263...103,457,462
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of IGI (PMID:21700773) MGI PMID:21700773 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Mcoln1 mucolipin 1 involved_in IMP
ISO
(PMID:18794901) UniProt
GO_Central
PMID:18794901 GO_REF:0000119 NCBI chr 8:3,550,458...3,565,232
Ensembl chr 8:3,550,457...3,565,232
JBrowse link
G Mcoln2 mucolipin 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 3:145,855,552...145,901,269
Ensembl chr 3:145,855,588...145,901,268
JBrowse link
G Mmgt1 membrane magnesium transporter 1 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:55,630,872...55,643,304
Ensembl chr  X:55,630,872...55,643,429
JBrowse link
G Scara5 scavenger receptor class A, member 5 involved_in IDA (PMID:19154717) UniProt PMID:19154717 NCBI chr14:65,903,852...66,002,275
Ensembl chr14:65,903,852...66,002,275
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 involved_in IEA
IBA
GOC
GO_Central
GO_REF:0000033 GO_REF:0000108 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 involved_in IEA
IBA
ISO
Ensembl
GO_Central
GOC
GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 GO_REF:0000119 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953
JBrowse link
G Slc25a28 solute carrier family 25, member 28 involved_in IEA GOC GO_REF:0000108 NCBI chr19:43,652,240...43,663,320
Ensembl chr19:43,652,240...43,663,320
JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 involved_in IDA
IMP
ISO
(PMID:21653899)
(PMID:20682781)
UniProt
GO_Central
PMID:20682781 PMID:21653899 GO_REF:0000119 NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874
JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 acts_upstream_of_or_within
involved_in
IGI
IBA
ISO
(PMID:21700773) MGI
GO_Central
PMID:21700773 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
JBrowse link
G Tfrc transferrin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc48a1 solute carrier family 48 (heme transporter), member 1 involved_in IMP (PMID:31571584) MGI PMID:31571584 NCBI chr15:97,682,246...97,690,573
Ensembl chr15:97,676,401...97,690,573
JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP-binding cassette, sub-family B member 6 involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000119 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 involved_in ISO
ISS
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000119 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin involved_in ISO RGD
GO_Central
PMID:26071548 GO_REF:0000096 RGD:401793712 NCBI chr19:24,236,909...24,257,954
Ensembl chr19:24,238,817...24,257,969
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit involved_in ISO RGD
GO_Central
PMID:26071548 GO_REF:0000096 RGD:401793712 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Slc25a28 solute carrier family 25, member 28 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:43,652,240...43,663,320
Ensembl chr19:43,652,240...43,663,320
JBrowse link
G Slc25a37 solute carrier family 25, member 37 involved_in ISO
IBA
IMP
(PMID:16511496) GO_Central
UniProt
PMID:16511496 GO_REF:0000033 GO_REF:0000119 NCBI chr14:69,479,297...69,522,993
Ensembl chr14:69,479,297...69,522,561
JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 involved_in IDA (PMID:15514116), (PMID:30647129) UniProt PMID:15514116 PMID:30647129 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 (metal ion transporter), member 8 involved_in ISO
ISS
IMP
IDA
(PMID:30015240)
(PMID:22898811)
GO_Central
UniProt
PMID:22898811 PMID:30015240 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 NCBI chr 3:135,522,644...135,594,333
Ensembl chr 3:135,531,040...135,594,333
JBrowse link
G Steap2 six transmembrane epithelial antigen of prostate 2 acts_upstream_of_or_within IDA (PMID:16609065) MGI PMID:16609065 NCBI chr 5:5,714,829...5,744,649
Ensembl chr 5:5,714,829...5,744,578
JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP-binding cassette, sub-family B member 7 involved_in ISS
ISO
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000119 NCBI chr  X:103,324,171...103,457,452
Ensembl chr  X:103,324,263...103,457,462
JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hamp2 hepcidin antimicrobial peptide 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106
JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:113,910,479...113,916,349
Ensembl chr 5:113,910,809...113,916,349
JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase, copper transporting, alpha polypeptide involved_in ISO RGD
GO_Central
PMID:24174620 GO_REF:0000096 RGD:11341686 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within
involved_in
IGI
IBA
(PMID:21700773) MGI
GO_Central
PMID:21700773 GO_REF:0000033 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hamp2 hepcidin antimicrobial peptide 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106
JBrowse link
G Nos1 nitric oxide synthase 1, neuronal involved_in ISO RGD
GO_Central
PMID:14752097 GO_REF:0000096 RGD:13824992 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Heph hephaestin involved_in IDA (PMID:30647129) UniProt PMID:30647129 NCBI chr  X:95,499,042...95,618,091
Ensembl chr  X:95,498,965...95,618,091
JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in IDA (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Lcn2 lipocalin 2 involved_in ISO RGD
GO_Central
PMID:25557118 GO_REF:0000096 RGD:126790477 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chr 7:140,801,297...140,801,406
Ensembl chr 7:140,801,297...140,801,406
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28632
    cellular process 18393
      transmembrane transport 1633
        inorganic ion transmembrane transport 988
          inorganic cation transmembrane transport 889
            iron ion transmembrane transport 28
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 4
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 6
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 5
              positive regulation of iron ion transmembrane transport + 4
              regulation of iron ion transmembrane transport + 9
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 28632
    localization 5646
      establishment of localization 5003
        transport 4680
          monoatomic ion transport 1335
            monoatomic cation transport 1132
              metal ion transport 980
                transition metal ion transport 109
                  iron ion transport 63
                    iron ion transmembrane transport 28
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 4
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 6
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 5
                      positive regulation of iron ion transmembrane transport + 4
                      regulation of iron ion transmembrane transport + 9
                      siderophore transmembrane transport 0
paths to the root