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ONTOLOGY REPORT - ANNOTATIONS


Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874



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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IDA (PMID:17192393) UniProt PMID:17192393 NCBI chr  X:75,051,048...75,156,283
Ensembl chr  X:75,051,048...75,156,732
JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of
IEA
ISO
(PMID:21700773) Ensembl
MGI
PMID:21700773 GO_REF:0000107 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IMP
IEA
(PMID:18794901) UniProt
Ensembl
PMID:18794901 GO_REF:0000107 NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009
JBrowse link
G MCOLN2 mucolipin TRP cation channel 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:84,925,583...84,997,113
Ensembl chr 1:84,925,583...84,997,113
JBrowse link
G MMGT1 membrane magnesium transporter 1 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:135,960,588...135,973,988
Ensembl chr  X:135,960,588...135,974,029
JBrowse link
G SCARA5 scavenger receptor class A member 5 involved_in ISS
IEA
UniProt
Ensembl
InterPro
GO_REF:0000002 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr 8:27,869,883...27,992,673
Ensembl chr 8:27,869,883...27,992,673
JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in IBA
IEA
GO_Central
GOC
GO_REF:0000033 GO_REF:0000108 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894
JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in IDA
IEA
IBA
(PMID:17293870) BHF-UCL
GOC
GO_Central
PMID:17293870 GO_REF:0000033 GO_REF:0000108 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
JBrowse link
G SLC25A28 solute carrier family 25 member 28 involved_in IEA GOC GO_REF:0000108 NCBI chr10:99,610,522...99,659,286
Ensembl chr10:99,610,519...99,622,793
JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in IMP
IEA
(PMID:20682781) UniProt
Ensembl
PMID:20682781 GO_REF:0000107 NCBI chr 8:22,367,278...22,434,129
Ensembl chr 8:22,367,278...22,434,129
JBrowse link
G SLC40A1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within
IMP
ISO
IBA
IEA
(PMID:12091367)
(PMID:21700773)
BHF-UCL
MGI
GO_Central
Ensembl
InterPro
PMID:12091367 PMID:21700773 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758
JBrowse link
G TTYH1 tweety family member 1 involved_in IEA GOC GO_REF:0000108 NCBI chr19:54,415,464...54,436,904
Ensembl chr19:54,415,219...54,436,904
JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC48A1 solute carrier family 48 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,753,934...47,782,751
Ensembl chr12:47,753,916...47,782,751
JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in IDA (PMID:33007128) UniProt PMID:33007128 NCBI chr 2:219,209,772...219,218,958
Ensembl chr 2:219,209,772...219,218,994
JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 involved_in IMP (PMID:24836561) UniProt PMID:24836561 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939
JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chr 9:69,035,752...69,079,076
Ensembl chr 9:69,035,751...69,079,076
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G SLC25A28 solute carrier family 25 member 28 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:99,610,522...99,659,286
Ensembl chr10:99,610,519...99,622,793
JBrowse link
G SLC25A37 solute carrier family 25 member 37 involved_in IEA
IBA
IMP
(PMID:35513392) Ensembl
GO_Central
UniProt
PMID:35513392 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 8:23,528,956...23,575,463
Ensembl chr 8:23,528,956...23,575,463
JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC40A1 solute carrier family 40 member 1 involved_in ISS
IEA
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758
JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC39A8 solute carrier family 39 member 8 involved_in IEA
IDA
(PMID:22898811) Ensembl
UniProt
PMID:22898811 GO_REF:0000107 NCBI chr 4:102,251,041...102,345,482
Ensembl chr 4:102,251,080...102,431,258
JBrowse link
G STEAP2 STEAP2 metalloreductase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16609065) Ensembl
MGI
PMID:16609065 GO_REF:0000107 NCBI chr 7:90,211,740...90,243,408
Ensembl chr 7:90,167,590...90,238,137
JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IMP (PMID:33157103) UniProt PMID:33157103 NCBI chr  X:75,051,048...75,156,283
Ensembl chr  X:75,051,048...75,156,732
JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAMP hepcidin antimicrobial peptide involved_in IDA (PMID:15514116), (PMID:29237594) BHF-UCL PMID:15514116 PMID:29237594 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISCU iron-sulfur cluster assembly enzyme involved_in IMP (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chr12:108,561,463...108,569,384
Ensembl chr12:108,562,582...108,569,368
JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha involved_in ISO
IEA
RGD
Ensembl
PMID:24174620 GO_REF:0000107 RGD:11341686 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395
JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21700773) Ensembl
GO_Central
MGI
PMID:21700773 GO_REF:0000033 GO_REF:0000107 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEPH hephaestin involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr  X:66,162,671...66,268,863
Ensembl chr  X:66,162,671...66,268,867
JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G MIR210 microRNA 210 involved_in IDA (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20497
    cellular process 19744
      transmembrane transport 1774
        inorganic ion transmembrane transport 1069
          inorganic cation transmembrane transport 974
            iron ion transmembrane transport 27
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 6
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 4
              regulation of iron ion transmembrane transport + 8
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 20497
    localization 5980
      establishment of localization 5318
        transport 4896
          monoatomic ion transport 1440
            monoatomic cation transport 1214
              metal ion transport 1013
                transition metal ion transport 111
                  iron ion transport 61
                    iron ion transmembrane transport 27
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 6
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 4
                      regulation of iron ion transmembrane transport + 8
                      siderophore transmembrane transport 0
paths to the root