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ONTOLOGY REPORT - ANNOTATIONS

Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:58,305,804...58,470,827
Ensembl chr  X:58,306,776...58,471,417 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21700773) Ensembl
MGI		 PMID:21700773 GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G MCOLN2 mucolipin TRP cation channel 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 6:62,956,797...63,008,527
Ensembl chr 6:62,956,804...63,200,612 		JBrowse link
G SCARA5 scavenger receptor class A member 5 involved_in IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr25:29,591,248...29,714,159
Ensembl chr25:29,591,294...29,712,173 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in IEA
IBA		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr27:3,788,785...3,823,852
Ensembl chr27:3,787,855...3,822,672 		JBrowse link
G SLC25A28 solute carrier family 25 member 28 involved_in IEA GOC GO_REF:0000108 NCBI chr28:12,533,639...12,543,906 JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,854,371...34,901,030
Ensembl chr25:34,846,653...34,869,695 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21700773) InterPro
GO_Central
MGI
Ensembl		 PMID:21700773 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr37:308,054...329,037
Ensembl chr37:303,104...368,865 		JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC48A1 solute carrier family 48 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:6,970,510...6,978,837
Ensembl chr27:6,971,402...6,978,942 		JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,760,478...25,767,753
Ensembl chr37:25,760,477...25,769,841 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:16,856,624...16,947,844
Ensembl chr34:16,856,633...16,946,422 		JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FXN frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chr 1:88,288,566...88,311,228
Ensembl chr 1:88,288,566...88,311,228 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G SLC25A28 solute carrier family 25 member 28 involved_in IBA GO_Central GO_REF:0000033 NCBI chr28:12,533,639...12,543,906 JBrowse link
G SLC25A37 solute carrier family 25 member 37 involved_in IEA
IBA		 Ensembl
GO_Central
UniProt		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr25:33,923,108...33,965,577
Ensembl chr25:33,894,132...33,965,398 		JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC40A1 solute carrier family 40 member 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr37:308,054...329,037
Ensembl chr37:303,104...368,865 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC39A8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:23,727,920...23,801,459
Ensembl chr32:23,729,476...23,800,941 		JBrowse link
G STEAP2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chr14:16,118,384...16,138,985
Ensembl chr14:16,119,073...16,135,238 		JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB7 ATP binding cassette subfamily B member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:58,305,804...58,470,827
Ensembl chr  X:58,306,776...58,471,417 		JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ISCU iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chr26:18,300,800...18,307,668
Ensembl chr26:18,300,803...18,307,652 		JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21700773) Ensembl
GO_Central
MGI		 PMID:21700773 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chr26:13,787,341...13,895,176
Ensembl chr26:13,786,309...13,962,332 		JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HEPH hephaestin involved_in ISO (PMID:30647129) UniProt PMID:30647129 NCBI chr  X:50,989,918...51,102,777
Ensembl chr  X:50,989,700...51,101,189 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:25557118 RGD:126790477 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22100
    cellular process 21630
      transmembrane transport 1714
        inorganic ion transmembrane transport 1001
          inorganic cation transmembrane transport 901
            iron ion transmembrane transport 24
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 5
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 3
              regulation of iron ion transmembrane transport + 7
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 22100
    localization 5633
      establishment of localization 4970
        transport 4611
          monoatomic ion transport 1343
            monoatomic cation transport 1144
              metal ion transport 971
                transition metal ion transport 123
                  iron ion transport 74
                    iron ion transmembrane transport 24
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 5
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 3
                      regulation of iron ion transmembrane transport + 7
                      siderophore transmembrane transport 0
paths to the root