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ONTOLOGY REPORT - ANNOTATIONS


Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISO (PMID:17192393) UniProt PMID:17192393 NCBI chrNW_004955562:1,079,884...1,220,806
Ensembl chrNW_004955562:1,077,198...1,221,061
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of ISO (PMID:21700773) MGI PMID:21700773 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:18794901) UniProt PMID:18794901 NCBI chrNW_004955563:1,703,408...1,712,908
Ensembl chrNW_004955563:1,703,416...1,745,996
JBrowse link
G Scara5 scavenger receptor class A member 5 involved_in ISO (PMID:19154717) UniProt PMID:19154717 NCBI chrNW_004955403:50,386,212...50,486,335
Ensembl chrNW_004955403:50,386,125...50,486,361
JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(PMID:21653899)
UniProt PMID:20682781 PMID:21653899 NCBI chrNW_004955403:45,828,247...45,867,309
Ensembl chrNW_004955403:45,827,942...45,867,309
JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12091367)
(PMID:21700773)
BHF-UCL
MGI
PMID:12091367 PMID:21700773 NCBI chrNW_004955403:9,253,734...9,271,732
Ensembl chrNW_004955403:9,253,734...9,271,916
JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc48a1 solute carrier family 48 member 1 involved_in ISO (PMID:31571584) MGI PMID:31571584 NCBI chrNW_004955500:6,675,631...6,691,942
Ensembl chrNW_004955500:6,679,908...6,691,942
JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in ISO (PMID:33007128) UniProt PMID:33007128 NCBI chrNW_004955453:14,215,104...14,222,338
Ensembl chrNW_004955453:14,215,408...14,222,172
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 involved_in ISO (PMID:24836561) UniProt PMID:24836561 NCBI chrNW_004955420:23,447,920...23,522,732
Ensembl chrNW_004955420:23,447,920...23,522,732
JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004955434:3,983,225...4,008,324
Ensembl chrNW_004955434:3,980,653...4,008,761
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26071548 RGD:401793712 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in ISO (PMID:35513392)
(PMID:16511496)
UniProt PMID:16511496 PMID:35513392 NCBI chrNW_004955403:46,697,560...46,739,082
Ensembl chrNW_004955403:46,697,560...46,739,903
JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 member 1 involved_in ISO (PMID:15514116), (PMID:30647129) UniProt PMID:15514116 PMID:30647129 NCBI chrNW_004955403:9,253,734...9,271,732
Ensembl chrNW_004955403:9,253,734...9,271,916
JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO (PMID:22898811)
(PMID:30015240)
UniProt PMID:22898811 PMID:30015240 RGD:15090842 NCBI chrNW_004955496:6,016,727...6,106,965
Ensembl chrNW_004955496:6,040,029...6,109,907
JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) MGI PMID:16609065 NCBI chrNW_004955432:7,455,731...7,499,863
Ensembl chrNW_004955432:7,456,514...7,490,381
JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISO (PMID:33157103) UniProt PMID:33157103 NCBI chrNW_004955562:1,079,884...1,220,806
Ensembl chrNW_004955562:1,077,198...1,221,061
JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116), (PMID:29237594) BHF-UCL PMID:15514116 PMID:29237594 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649
JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chrNW_004955455:9,833,924...9,840,547
Ensembl chrNW_004955455:9,833,924...9,841,619
JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha ISO RGD PMID:24174620 RGD:11341686 NCBI chrNW_004955557:1,355,471...1,515,725
Ensembl chrNW_004955557:1,355,397...1,515,393
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (PMID:21700773) MGI PMID:21700773 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649
JBrowse link
G Nos1 nitric oxide synthase 1 ISO RGD PMID:14752097 RGD:13824992 NCBI chrNW_004955455:13,797,557...13,978,402
Ensembl chrNW_004955455:13,797,545...13,972,566
JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Heph hephaestin involved_in ISO (PMID:30647129) UniProt PMID:30647129 NCBI chrNW_004955475:5,625,177...5,704,234
Ensembl chrNW_004955475:5,625,150...5,704,234
JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:29061364) ARUK-UCL PMID:29061364 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12600
    cellular process 12034
      transmembrane transport 1030
        inorganic ion transmembrane transport 617
          inorganic cation transmembrane transport 569
            iron ion transmembrane transport 19
              heme transmembrane transport + 3
              iron import into the mitochondrion 3
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 4
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 2
              regulation of iron ion transmembrane transport + 6
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 12600
    localization 4342
      establishment of localization 3713
        transport 3445
          monoatomic ion transport 906
            monoatomic cation transport 788
              metal ion transport 725
                transition metal ion transport 83
                  iron ion transport 45
                    iron ion transmembrane transport 19
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 3
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 4
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 2
                      regulation of iron ion transmembrane transport + 6
                      siderophore transmembrane transport 0
paths to the root