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ONTOLOGY REPORT - ANNOTATIONS

Term:iron ion transmembrane transport
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Accession:GO:0034755 term browser browse the term
Definition:A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Comment:Note that this term is not intended for use in annotating lateral movement within membranes.
Synonyms:exact_synonym: iron ion membrane transport;   transmembrane iron transport
 narrow_synonym: ferrous ion transmembrane transport;   ferrous iron transmembrane transport;   high affinity ferrous ion transmembrane transport;   high affinity iron ion transport;   high-affinity iron ion transmembrane transport;   iron(2+) transmembrane transport;   low affinity iron ion transport;   low-affinity iron ion transmembrane transport
 alt_id: GO:0000040;   GO:0006827;   GO:0061839;   GO:1903874


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iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17192393)		 UniProt
RGD		 PMID:17192393 GO_REF:0000024 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of ISO MGI:1315204 (PMID:21700773) RGD PMID:21700773 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:18794901) RGD PMID:18794901 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252 		JBrowse link
G Mcoln2 mucolipin TRP cation channel 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:134,408,463...134,420,798
Ensembl chr  X:134,408,466...134,420,729 		JBrowse link
G Scara5 scavenger receptor class A, member 5 involved_in ISO (MGI:3833042|PMID:19154717) RGD PMID:19154717 MGI:3833042 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in ISO
IBA
IEA		 (PMID:17293870)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:17293870 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 involved_in ISO (PMID:20682781)
(MGI:5295560|PMID:21653899), (MGI:6392986|PMID:20682781)		 RGD PMID:20682781 PMID:21653899 MGI:5295560 MGI:6392986 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:12091367)
MGI:1933533 (MGI:1859678|PMID:10828623), (PMID:21700773)
GO_REF:0000033
GO_REF:0000002		 RGD
GO_Central
InterPro		 PMID:10828623 PMID:12091367 PMID:21700773 GO_REF:0000002 GO_REF:0000033 MGI:1859678 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
heme export from vacuole to cytoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc48a1 solute carrier family 48 member 1 involved_in ISO MGI:6711492 (PMID:31571584) RGD PMID:31571584 NCBI chr 7:128,915,136...128,923,929
Ensembl chr 7:128,915,195...128,923,024 		JBrowse link
heme transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb6 ATP binding cassette subfamily B member 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:33007128)		 UniProt
RGD		 PMID:33007128 GO_REF:0000024 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 involved_in ISO
ISS
IEA		 (PMID:24836561)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:24836561 GO_REF:0000024 GO_REF:0000107 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
iron import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin IMP RGD PMID:26071548 RGD:401793712 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:26071548 RGD:401793712 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Slc25a28 solute carrier family 25 member 28 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:242,530,877...242,542,140
Ensembl chr 1:242,530,899...242,542,115 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in ISO
IBA
IEA		 (MGI:3690197|PMID:16511496)
GO_REF:0000033
GO_REF:0000117
(PMID:35513392)		 RGD
GO_Central
UniProt		 PMID:16511496 PMID:35513392 GO_REF:0000033 GO_REF:0000117 MGI:3690197 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
iron ion export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc40a1 solute carrier family 40 member 1 involved_in ISO
ISS		 (MGI:3521561|PMID:15514116)
GO_REF:0000024		 RGD
UniProt		 PMID:15514116 GO_REF:0000024 MGI:3521561 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc39a8 solute carrier family 39 member 8 involved_in ISO
IDA		 (PMID:22898811)
(MGI:6383325|PMID:30015240), (MGI:7339319|PMID:22898811)		 RGD PMID:22898811 PMID:30015240 PMID:22898811 MGI:6383325 MGI:7339319, RGD:15090842 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
G Steap2 STEAP2 metalloreductase acts_upstream_of_or_within ISO (PMID:16609065) RGD PMID:16609065 NCBI chr 4:28,347,769...28,368,177
Ensembl chr 4:28,348,362...28,375,791 		JBrowse link
iron-sulfur cluster export from the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:33157103)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:33157103 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
negative regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO
IEA		 (PMID:15514116)
GO_REF:0000107
(PMID:29237594)		 RGD
Ensembl		 PMID:15514116 PMID:29237594 GO_REF:0000107 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150 		JBrowse link
negative regulation of iron ion transmembrane transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha IMP RGD PMID:24174620 RGD:11341686 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1315204 (PMID:21700773)		 GO_Central
RGD		 PMID:21700773 GO_REF:0000033 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:14752097 RGD:13824992 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
negative regulation of iron ion transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hamp hepcidin antimicrobial peptide involved_in ISO (PMID:15514116) RGD PMID:15514116 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
positive regulation of iron export across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Heph hephaestin involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (MGI:6304699|PMID:29061364) RGD PMID:29061364 MGI:6304699 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    cellular process 18525
      transmembrane transport 1704
        inorganic ion transmembrane transport 1003
          inorganic cation transmembrane transport 905
            iron ion transmembrane transport 26
              heme transmembrane transport + 3
              iron import into the mitochondrion 4
              iron ion export across plasma membrane + 3
              iron ion import across cell outer membrane 0
              iron ion import across plasma membrane + 6
              iron-sulfur cluster transmembrane transport + 1
              negative regulation of iron ion transmembrane transport + 4
              positive regulation of iron ion transmembrane transport + 4
              regulation of iron ion transmembrane transport + 8
              siderophore transmembrane transport 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    localization 5683
      establishment of localization 4990
        transport 4683
          monoatomic ion transport 1387
            monoatomic cation transport 1173
              metal ion transport 992
                transition metal ion transport 128
                  iron ion transport 84
                    iron ion transmembrane transport 26
                      heme transmembrane transport + 3
                      iron import into the mitochondrion 4
                      iron ion export across plasma membrane + 3
                      iron ion import across cell outer membrane 0
                      iron ion import across plasma membrane + 6
                      iron-sulfur cluster transmembrane transport + 1
                      negative regulation of iron ion transmembrane transport + 4
                      positive regulation of iron ion transmembrane transport + 4
                      regulation of iron ion transmembrane transport + 8
                      siderophore transmembrane transport 0
paths to the root