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ONTOLOGY REPORT - ANNOTATIONS


Term:SMN-Sm protein complex
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Accession:GO:0034719 term browser browse the term
Definition:A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.
Comment:Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797.
Synonyms:broad_synonym: SMN-containing protein complex


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SMN-Sm protein complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07042226.1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:150,660,743...150,666,309 JBrowse link
G Ddx20 DEAD-box helicase 20 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 2:208,144,142...208,154,764
Ensembl chr 2:208,144,139...208,152,179
JBrowse link
G Gemin2 gem (nuclear organelle) associated protein 2 part_of ISS
ISO
GO_REF:0000024
(PMID:18984161)
UniProt
RGD
PMID:18984161 GO_REF:0000024 NCBI chr 6:80,108,751...80,122,382
Ensembl chr 6:80,108,655...80,122,365
JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr10:64,364,808...64,375,885
Ensembl chr10:64,368,809...64,375,816
JBrowse link
G Gemin5 gem (nuclear organelle) associated protein 5 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr10:43,552,260...43,599,241
Ensembl chr10:43,554,046...43,599,232
JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 6:2,907,040...2,911,577
Ensembl chr 6:2,907,145...2,911,559
JBrowse link
G Gemin7 gem (nuclear organelle) associated protein 7 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 1:80,473,966...80,487,976
Ensembl chr 1:80,473,966...80,483,487
JBrowse link
G Gemin7l1 gem (nuclear organelle) associated protein 7-like 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:78,954,274...78,955,038
Ensembl chr 4:78,954,599...78,954,997
JBrowse link
G Gemin8 gem (nuclear organelle) associated protein 8 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr  X:29,806,605...29,825,439
Ensembl chr  X:29,806,606...29,825,439
JBrowse link
G LOC687679 similar to small nuclear ribonucleoprotein polypeptide G part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:91,588,215...91,588,629
Ensembl chr 4:118,167,294...118,174,842
Ensembl chr 1:118,167,294...118,174,842
JBrowse link
G Smn1 survival of motor neuron 1, telomeric part_of ISS
ISO
GO_REF:0000024
(PMID:18984161)
UniProt
RGD
PMID:18984161 GO_REF:0000024 NCBI chr 2:30,360,101...30,371,147
Ensembl chr 2:30,360,100...30,371,147
JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 part_of ISS
ISO
GO_REF:0000024
(PMID:18984161)
UniProt
RGD
PMID:18984161 GO_REF:0000024 NCBI chr 3:122,696,125...122,703,734
Ensembl chr 3:122,695,939...122,703,734
JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide part_of ISO
IBA
(PMID:18984161)
PMID:21873635
RGD PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr18:1,866,066...1,876,613
Ensembl chr18:1,866,080...1,876,613
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 1:80,057,140...80,059,990
Ensembl chr 1:80,056,755...80,059,996
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide part_of IBA
ISO
PMID:21873635
(PMID:18984161)
RGD PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr20:14,080,562...14,095,644
Ensembl chr20:14,080,565...14,095,181
JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr13:50,252,707...50,258,951
Ensembl chr 8:129,371,556...129,371,973
JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 7:34,478,331...34,485,034
Ensembl chr 7:34,478,331...34,485,034
JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G part_of ISO
IBA
(PMID:18984161)
PMID:21873635
RGD PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr 4:118,167,267...118,174,846
Ensembl chr 4:118,167,294...118,174,842
JBrowse link
G Strap serine/threonine kinase receptor associated protein part_of ISO
ISS
(PMID:18984161)
GO_REF:0000024
RGD
UniProt
PMID:18984161 GO_REF:0000024 NCBI chr 4:171,730,629...171,744,877
Ensembl chr 4:171,730,635...171,745,377
JBrowse link
SMN complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx20 DEAD-box helicase 20 part_of ISO
IBA
(PMID:18984161)
PMID:21873635
RGD PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr 2:208,144,142...208,154,764
Ensembl chr 2:208,144,139...208,152,179
JBrowse link
G Fmr1 FMRP translational regulator 1 colocalizes_with
part_of
ISO
IEA
ISS
(PMID:18093976)
(MGI:5763366|PMID:18093976)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18093976 GO_REF:0000024 GO_REF:0000107 MGI:5763366 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Gemin2 gem (nuclear organelle) associated protein 2 part_of ISO
ISS
IBA
(PMID:18984161)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:18984161, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 6:80,108,751...80,122,382
Ensembl chr 6:80,108,655...80,122,365
JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 part_of ISO
IBA
(PMID:18984161)
PMID:21873635
RGD PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr10:64,364,808...64,375,885
Ensembl chr10:64,368,809...64,375,816
JBrowse link
G Gemin5 gem (nuclear organelle) associated protein 5 part_of ISO (PMID:18984161), (PMID:20513430) RGD PMID:18984161 PMID:20513430 NCBI chr10:43,552,260...43,599,241
Ensembl chr10:43,554,046...43,599,232
JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 part_of ISO
IBA
(PMID:18984161)
PMID:21873635
RGD PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr 6:2,907,040...2,911,577
Ensembl chr 6:2,907,145...2,911,559
JBrowse link
G Gemin7 gem (nuclear organelle) associated protein 7 part_of ISO (PMID:18984161) RGD PMID:18984161 NCBI chr 1:80,473,966...80,487,976
Ensembl chr 1:80,473,966...80,483,487
JBrowse link
G Gemin8 gem (nuclear organelle) associated protein 8 part_of ISO
IBA
(PMID:16434402), (PMID:18984161)
PMID:21873635
RGD PMID:16434402 PMID:18984161, PMID:21873635 RGD:13792537 NCBI chr  X:29,806,605...29,825,439
Ensembl chr  X:29,806,606...29,825,439
JBrowse link
G Smn1 survival of motor neuron 1, telomeric part_of ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:11283611), (PMID:18093976), (PMID:18984161)
UniProt
RGD
PMID:11283611 PMID:18093976 PMID:18984161, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:30,360,101...30,371,147
Ensembl chr 2:30,360,100...30,371,147
JBrowse link
G Strap serine/threonine kinase receptor associated protein part_of IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:18984161)
UniProt
RGD
PMID:18984161, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:171,730,629...171,744,877
Ensembl chr 4:171,730,635...171,745,377
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20138
    cellular anatomical entity 19840
      cytoplasm 11424
        SMN-Sm protein complex 20
          Lsm-containing SMN-Sm protein complex 0
          SMN complex 10
          SmD-containing SMN-Sm protein complex 0
Path 2
Term Annotations click to browse term
  cellular_component 20138
    cellular anatomical entity 19840
      intracellular anatomical structure 14441
        cytoplasm 11424
          SMN-Sm protein complex 20
            Lsm-containing SMN-Sm protein complex 0
            SMN complex 10
            SmD-containing SMN-Sm protein complex 0
paths to the root