Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:cortisol metabolic process
go back to main search page
Accession:GO:0034650 term browser browse the term
Definition:The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
Synonyms:exact_synonym: cortisol metabolism


show annotations for term's descendants           Sort by:
cortisol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:53,280,110...53,310,868
Ensembl chr15:72,901,286...72,931,164 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:139,584,976...139,592,466
Ensembl chr 8:142,629,127...142,634,654 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:139,622,632...139,630,014
Ensembl chr 8:142,666,534...142,672,575 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:50,500,103...50,520,487
Ensembl chr20:51,721,685...51,742,716 		JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:106,042,235...106,076,840
Ensembl chr2B:224,637,238...224,671,474 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822 		JBrowse link
G CYP27C1 cytochrome P450 family 27 subfamily C member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:33,057,718...33,092,809
Ensembl chr2B:127,859,318...127,872,150 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,776,118...47,782,861
Ensembl chr16:67,165,215...67,171,417 		JBrowse link
cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:139,584,976...139,592,466
Ensembl chr 8:142,629,127...142,634,654 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in
NOT|involved_in		 IEA
ISO		 (PMID:9703385) Ensembl
BHF-UCL		 PMID:9703385 GO_REF:0000107 NCBI chr 8:139,622,632...139,630,014
Ensembl chr 8:142,666,534...142,672,575 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGKQ diacylglycerol kinase theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,075,133...1,090,081
Ensembl chr 4:994,985...1,007,724 		JBrowse link
G H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,996,315...8,031,987
Ensembl chr 1:9,232,666...9,256,631 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      cellular metabolic process 8633
        cellular ketone metabolic process 238
          cortisol metabolic process 16
            cortisol biosynthetic process + 10
Path 2
Term Annotations click to browse term
  biological_process 16440
    metabolic process 10303
      organic substance metabolic process 9869
        organic cyclic compound metabolic process 5562
          steroid metabolic process 302
            glucocorticoid metabolic process 29
              cortisol metabolic process 16
                cortisol biosynthetic process + 10
paths to the root