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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K4me/H3K4me2/H3K4me3 demethylase activity
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Accession:GO:0034647 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/di/monomethyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4-me3 specific);   histone demethylase activity (H3-trimethyl-K4 specific)
 broad_synonym: histone H3-K4me2 demethylase activity;   histone H3K4me2 demethylase activity
 related_synonym: H3K4me3 demethylase activity;   histone H3-K4me3 demethylase activity
 xref: EC:1.14.11.67;   RHEA:60208



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histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) RGD PMID:19407342 PMID:19727073 NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800
JBrowse link
G Kdm5a lysine demethylase 5A enables ISO
IBA
(PMID:18270511)
GO_REF:0000033
RGD
GO_Central
PMID:18270511 GO_REF:0000033 NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:153,565,846...153,642,422
JBrowse link
G Kdm5b lysine demethylase 5B enables ISO
IBA
(PMID:20228790), (PMID:20403335)
GO_REF:0000033
RGD
GO_Central
PMID:20228790 PMID:20403335 GO_REF:0000033 NCBI chr13:48,554,367...48,625,721
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdm5c lysine demethylase 5C enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:21,345,459...21,387,045
Ensembl chr  X:21,345,481...21,381,870
JBrowse link
G Kdm5d lysine demethylase 5D enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  Y:551,621...647,742
Ensembl chr  Y:530,401...624,018
JBrowse link
G Riox1 ribosomal oxygenase 1 enables ISO (PMID:19927124) RGD PMID:19927124 NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      oxidoreductase activity 869
        dioxygenase activity 100
          2-oxoglutarate-dependent dioxygenase activity 64
            histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      demethylase activity 42
        protein demethylase activity 30
          histone demethylase activity 30
            histone H3 demethylase activity 26
              histone H3K4 demethylase activity 8
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
paths to the root