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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K4me/H3K4me2/H3K4me3 demethylase activity
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Accession:GO:0034647 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/di/monomethyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4-me3 specific);   histone demethylase activity (H3-trimethyl-K4 specific)
 broad_synonym: histone H3-K4me2 demethylase activity;   histone H3K4me2 demethylase activity
 related_synonym: H3K4me3 demethylase activity;   histone H3-K4me3 demethylase activity
 xref: EC:1.14.11.67;   RHEA:60208


show annotations for term's descendants           Sort by:
histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1B lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chr 7:13,846,283...13,902,912
Ensembl chr 7:13,845,942...13,901,255 		JBrowse link
G KDM5A lysine demethylase 5A enables IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:67,628,791...67,716,143
Ensembl chr 5:67,629,380...67,715,905 		JBrowse link
G KDM5B lysine demethylase 5B enables IEA
IBA		 UniProt
Ensembl
GO_Central		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 NCBI chr10:24,739,115...24,831,537
Ensembl chr10:24,736,838...24,831,447 		JBrowse link
G KDM5C lysine demethylase 5C enables IEA
IBA		 RHEA
UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  X:45,968,812...46,003,215
Ensembl chr  X:45,968,814...46,003,215 		JBrowse link
G LOC110257883 lysine-specific demethylase 5D-like enables IEA
IBA		 UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000033 NCBI chr  Y:39,582,253...39,631,823
Ensembl chr  Y:39,582,815...39,631,815 		JBrowse link
G RIOX1 ribosomal oxygenase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:96,823,073...96,831,582
Ensembl chr 7:96,823,130...96,827,719 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19431
    catalytic activity 5614
      oxidoreductase activity 733
        dioxygenase activity 96
          2-oxoglutarate-dependent dioxygenase activity 62
            histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
Path 2
Term Annotations click to browse term
  molecular_function 19431
    catalytic activity 5614
      demethylase activity 41
        protein demethylase activity 31
          histone demethylase activity 31
            histone H3 demethylase activity 28
              histone H3K4 demethylase activity 8
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
paths to the root