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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K4me/H3K4me2/H3K4me3 demethylase activity
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Accession:GO:0034647 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/di/monomethyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4-me3 specific);   histone demethylase activity (H3-trimethyl-K4 specific)
 broad_synonym: histone H3-K4me2 demethylase activity;   histone H3K4me2 demethylase activity
 related_synonym: H3K4me3 demethylase activity;   histone H3-K4me3 demethylase activity
 xref: EC:1.14.11.67;   RHEA:60208


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histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chrNW_004624756:8,447,780...8,506,870
Ensembl chrNW_004624756:8,449,585...8,506,858
JBrowse link
G Kdm5a lysine demethylase 5A enables IEA UniProt
TreeGrafter
GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004624735:8,473,778...8,631,964
Ensembl chrNW_004624735:8,530,016...8,631,954
Ensembl chrNW_004624735:8,530,016...8,631,954
JBrowse link
G Kdm5b lysine demethylase 5B enables IEA UniProt
TreeGrafter
GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004624807:8,011,731...8,091,352
Ensembl chrNW_004624807:8,011,878...8,093,758
JBrowse link
G Kdm5c lysine demethylase 5C enables IEA UniProt
TreeGrafter
GO_REF:0000003 GO_REF:0000118 NCBI chrNW_004624909:421,033...455,201
Ensembl chrNW_004624909:420,077...455,309
JBrowse link
G Riox1 ribosomal oxygenase 1 enables ISO (PMID:19927124) UniProt PMID:19927124 NCBI chrNW_004624734:27,958,942...27,961,917 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18439
    catalytic activity 5599
      oxidoreductase activity 699
        dioxygenase activity 91
          2-oxoglutarate-dependent dioxygenase activity 58
            histone H3K4me/H3K4me2/H3K4me3 demethylase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 18439
    catalytic activity 5599
      demethylase activity 37
        protein demethylase activity 28
          histone demethylase activity 28
            histone H3 demethylase activity 26
              histone H3K4 demethylase activity 7
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 5
paths to the root