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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K4me/H3K4me2/H3K4me3 demethylase activity
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Accession:GO:0034647 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/di/monomethyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4-me3 specific);   histone demethylase activity (H3-trimethyl-K4 specific)
 broad_synonym: histone H3-K4me2 demethylase activity;   histone H3K4me2 demethylase activity
 related_synonym: H3K4me3 demethylase activity;   histone H3-K4me3 demethylase activity
 xref: EC:1.14.11.67;   RHEA:60208



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histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1b lysine (K)-specific demethylase 1B NOT|enables IDA (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chr13:47,196,849...47,238,085
Ensembl chr13:47,196,975...47,238,755
JBrowse link
G Kdm5a lysine demethylase 5A enables IEA
ISO
IBA
UniProt
GO_Central
RHEA
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 GO_REF:0000119 NCBI chr 6:120,341,060...120,421,535
Ensembl chr 6:120,341,085...120,421,535
JBrowse link
G Kdm5b lysine demethylase 5B enables ISO
ISS
IBA
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:134,487,916...134,560,621
Ensembl chr 1:134,487,909...134,563,023
JBrowse link
G Kdm5c lysine demethylase 5C enables IEA
IBA
UniProt
RHEA
GO_Central
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  X:151,015,698...151,062,098
Ensembl chr  X:151,016,016...151,057,531
JBrowse link
G Kdm5d lysine demethylase 5D enables IEA
IBA
UniProt
RHEA
GO_Central
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116 NCBI chr  Y:897,566...946,316
Ensembl chr  Y:897,788...956,786
JBrowse link
G Riox1 ribosomal oxygenase 1 enables IDA (PMID:19927124) UniProt PMID:19927124 NCBI chr12:83,997,382...83,999,727
Ensembl chr12:83,997,382...83,999,725
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28772
    catalytic activity 5722
      oxidoreductase activity 794
        dioxygenase activity 94
          2-oxoglutarate-dependent dioxygenase activity 63
            histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
Path 2
Term Annotations click to browse term
  molecular_function 28772
    catalytic activity 5722
      demethylase activity 45
        protein demethylase activity 30
          histone demethylase activity 30
            histone H3 demethylase activity 26
              histone H3K4 demethylase activity 8
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 6
paths to the root