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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K4me/H3K4me2/H3K4me3 demethylase activity
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Accession:GO:0034647 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/di/monomethyl-lysine-4 demethylase activity;   histone demethylase activity (H3-K4-me3 specific);   histone demethylase activity (H3-trimethyl-K4 specific)
 broad_synonym: histone H3-K4me2 demethylase activity;   histone H3K4me2 demethylase activity
 related_synonym: H3K4me3 demethylase activity;   histone H3-K4me3 demethylase activity
 xref: EC:1.14.11.67;   RHEA:60208


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histone H3K4me/H3K4me2/H3K4me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KDM1B lysine demethylase 1B NOT|enables ISO (PMID:19407342), (PMID:19727073) UniProt PMID:19407342 PMID:19727073 NCBI chr17:53,919,859...53,987,326
Ensembl chr17:53,921,702...53,987,124
JBrowse link
G KDM5A lysine demethylase 5A enables IEA UniProt
Ensembl
TreeGrafter
GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr11:285,206...381,481
Ensembl chr11:286,728...381,430
JBrowse link
G KDM5B lysine demethylase 5B enables IEA UniProt
Ensembl
TreeGrafter
GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr25:26,599,740...26,685,256
Ensembl chr25:26,600,736...26,683,632
JBrowse link
G KDM5C lysine demethylase 5C enables IEA UniProt
TreeGrafter
GO_REF:0000003 GO_REF:0000118 NCBI chr  X:49,306,472...49,356,151
Ensembl chr  X:49,321,173...49,356,100
JBrowse link
G RIOX1 ribosomal oxygenase 1 enables ISO (PMID:19927124) UniProt PMID:19927124 NCBI chr24:50,744,200...50,746,925 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19846
    catalytic activity 5465
      oxidoreductase activity 717
        dioxygenase activity 91
          2-oxoglutarate-dependent dioxygenase activity 59
            histone H3K4me/H3K4me2/H3K4me3 demethylase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 19846
    catalytic activity 5465
      demethylase activity 37
        protein demethylase activity 26
          histone demethylase activity 26
            histone H3 demethylase activity 24
              histone H3K4 demethylase activity 7
                histone H3K4me/H3K4me2/H3K4me3 demethylase activity 5
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