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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to unfolded protein
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Accession:GO:0034620 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
Comment:Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER.
Synonyms:related_synonym: heat shock protein activity



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cellular response to unfolded protein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:116,221,747...116,248,692
Ensembl chr10:119,643,963...119,665,964
JBrowse link
G DAXX death domain associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,890,846...32,895,307
Ensembl chr 6:34,004,543...34,008,717
JBrowse link
G DERL1 derlin 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4361100|PMID:19509052) MGI
Ensembl
PMID:19509052 GO_REF:0000107 MGI:4361100 NCBI chr 8:119,707,397...119,736,502
Ensembl chr 8:122,463,063...122,492,137
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) ParkinsonsUK-UCL PMID:20625543 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPB8 heat shock protein family B (small) member 8 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr12:116,758,785...116,774,883
Ensembl chr12:120,136,986...120,153,102
JBrowse link
G OPTN optineurin involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:13,104,335...13,142,725
Ensembl chr10:13,077,345...13,115,773
JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (MGI:5517729|PMID:23847051) MGI PMID:23847051 MGI:5517729 NCBI chr17:36,389,549...36,425,161
Ensembl chr17:41,038,302...41,073,872
JBrowse link
G RHBDD1 rhomboid domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:114,041,381...114,245,220
Ensembl chr2B:232,897,487...233,057,578
JBrowse link
G TM7SF3 transmembrane 7 superfamily member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:59,298,725...59,340,896
Ensembl chr12:61,913,370...61,955,540
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:38,986,844...39,010,307
Ensembl chr12:39,879,951...39,902,303
JBrowse link
G UMOD uromodulin acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5916257|PMID:28437467) MGI
Ensembl
PMID:28437467 GO_REF:0000107 MGI:5916257 NCBI chr16:17,960,456...17,980,338
Ensembl chr16:20,430,085...20,449,121
JBrowse link
endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMFR autocrine motility factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:36,647,792...36,711,782
Ensembl chr16:55,780,633...55,843,744
JBrowse link
G ATF3 activating transcription factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150
JBrowse link
G ATF4 activating transcription factor 4 involved_in ISO (MGI:5496937|PMID:23624402) UniProt PMID:23624402 MGI:5496937 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
JBrowse link
G BHLHA15 basic helix-loop-helix family member a15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:6,306,929...6,311,026
Ensembl chr 7:103,677,022...103,677,593
JBrowse link
G CCND1 cyclin D1 acts_upstream_of_or_within ISO (MGI:3620306|PMID:16176978) MGI PMID:16176978 MGI:3620306 NCBI chr11:64,737,006...64,750,353 JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in ISO (PMID:23152784) UniProt PMID:23152784 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 involved_in ISO (MGI:4438316|PMID:19767743) UniProt PMID:19767743 MGI:4438316 NCBI chr11:46,236,384...46,280,145
Ensembl chr11:46,788,561...46,830,246
JBrowse link
G DDIT3 DNA damage inducible transcript 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3525819|PMID:15601821)
(MGI:6270315|PMID:30188326)
MGI
Ensembl
PMID:15601821 PMID:30188326 GO_REF:0000107 MGI:3525819 MGI:6270315 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G DERL1 derlin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:119,707,397...119,736,502
Ensembl chr 8:122,463,063...122,492,137
JBrowse link
G DERL2 derlin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,519,183...5,534,145
Ensembl chr17:5,514,440...5,526,363
JBrowse link
G DERL3 derlin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:4,589,448...4,594,628
Ensembl chr22:22,673,908...22,678,444
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3511630|PMID:15542627) MGI
Ensembl
PMID:15542627 GO_REF:0000107 MGI:3511630 NCBI chr2A:37,130,386...37,184,587
Ensembl chr2A:37,895,814...37,941,686
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1333015|PMID:9930704), (MGI:2677605|PMID:14517290)
(MGI:1858648|PMID:10882126), (MGI:2136067|PMID:11430819), (MGI:3511630|PMID:15542627), (MGI:3583403|PMID:15911877), (MGI:3620306|PMID:16176978)
MGI
Ensembl
PMID:9930704 PMID:10882126 PMID:11430819 PMID:14517290 PMID:15542627 More... GO_REF:0000107 MGI:1333015 MGI:1858648 MGI:2136067 MGI:2677605 MGI:3511630 MGI:3583403 MGI:3620306 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 acts_upstream_of_or_within ISO (MGI:3620306|PMID:16176978) MGI PMID:16176978 MGI:3620306 NCBI chr15:18,871,867...18,973,380
Ensembl chr15:37,120,044...37,229,211
JBrowse link
G ERLEC1 endoplasmic reticulum lectin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr2A:53,930,280...53,962,178
Ensembl chr2A:54,842,228...54,874,068
JBrowse link
G ERMP1 endoplasmic reticulum metallopeptidase 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:27566589) FlyBase
Ensembl
PMID:27566589 GO_REF:0000107 NCBI chr 9:5,605,122...5,653,661
Ensembl chr 9:5,787,920...5,836,388
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1858648|PMID:10882126), (MGI:2136067|PMID:11430819), (MGI:3525819|PMID:15601821) MGI
Ensembl
InterPro
PMID:10882126 PMID:11430819 PMID:15601821 GO_REF:0000002 GO_REF:0000107 MGI:1858648 MGI:2136067 MGI:3525819 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:14,397,697...14,420,618
Ensembl chr16:23,940,716...23,963,894
JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3525819|PMID:15601821) MGI
Ensembl
PMID:15601821 GO_REF:0000107 MGI:3525819 NCBI chr14:33,236,087...33,292,127
Ensembl chr14:51,520,048...51,575,798
JBrowse link
G FGF21 fibroblast growth factor 21 ISO RGD PMID:23123503 RGD:10401883 NCBI chr19:45,755,466...45,758,472 JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:1913176|PMID:10922362) RGD
Ensembl
MGI
PMID:10922362 PMID:15102845 GO_REF:0000107 MGI:1913176 RGD:1304324 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISO (MGI:4437543|PMID:19816510) BHF-UCL PMID:19816510 MGI:4437543 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (MGI:3583403|PMID:15911877) MGI PMID:15911877 MGI:3583403 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2677605|PMID:14517290) MGI
Ensembl
PMID:14517290 GO_REF:0000107 MGI:2677605 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G OS9 OS9 endoplasmic reticulum lectin involved_in IEA InterPro GO_REF:0000002 NCBI chr12:31,205,239...31,232,769
Ensembl chr12:31,463,716...31,493,076
JBrowse link
G PARP16 poly(ADP-ribose) polymerase family member 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:44,163,785...44,231,895
Ensembl chr15:62,485,144...62,513,722
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A acts_upstream_of_or_within ISO (MGI:3525819|PMID:15601821) RGD
MGI
PMID:15601821 PMID:18266951 PMID:22154936 MGI:3525819 RGD:9999171 RGD:9999413 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G QRICH1 glutamine rich 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:48,954,345...49,018,745
Ensembl chr 3:50,035,676...50,097,596
JBrowse link
G SELENOS selenoprotein S involved_in ISO (PMID:15215856) UniProt PMID:15215856 NCBI chr15:79,995,678...80,002,159
Ensembl chr15:99,279,203...99,285,682
JBrowse link
G SERP1 stress associated endoplasmic reticulum protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3619104|PMID:16415102) MGI
Ensembl
PMID:16415102 GO_REF:0000107 MGI:3619104 NCBI chr 3:147,559,607...147,564,668
Ensembl chr 3:155,133,115...155,137,241
JBrowse link
G STC2 stanniocalcin 2 acts_upstream_of_or_within ISO (MGI:3511371|PMID:15485913) MGI PMID:15485913 MGI:3511371 NCBI chr 5:168,668,851...168,681,274
Ensembl chr 5:175,575,419...175,587,832
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:694,414...696,682 JBrowse link
G TBL2 transducin beta like 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:80,721,616...80,730,685 JBrowse link
G TMTC4 transmembrane O-mannosyltransferase targeting cadherins 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:6270315|PMID:30188326) MGI
Ensembl
PMID:30188326 GO_REF:0000107 MGI:6270315 NCBI chr13:81,771,668...81,841,926
Ensembl chr13:100,910,277...100,976,164
JBrowse link
G VAPB VAMP associated protein B and C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:54,736,035...54,798,155
Ensembl chr20:56,010,782...56,064,363
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (MGI:5573106|PMID:24753614), (MGI:5607242|PMID:17612490) RGD
UniProt
PMID:15171721 PMID:17612490 PMID:24753614 MGI:5573106 MGI:5607242 RGD:1304536 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
G YOD1 YOD1 deubiquitinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,646,727...182,655,141
Ensembl chr 1:186,930,209...186,932,225
JBrowse link
IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G PARP16 poly(ADP-ribose) polymerase family member 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:44,163,785...44,231,895
Ensembl chr15:62,485,144...62,513,722
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
G VAPB VAMP associated protein B and C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:54,736,035...54,798,155
Ensembl chr20:56,010,782...56,064,363
JBrowse link
mitochondrial unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB10 ATP binding cassette subfamily B member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:205,061,329...205,103,568
Ensembl chr 1:210,094,355...210,134,496
JBrowse link
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6B activating transcription factor 6 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,762,161...31,775,136
Ensembl chr 6:32,643,124...32,655,617
JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor involved_in ISO (PMID:18391022) UniProt PMID:18391022 NCBI chr 5:168,409,668...168,492,678
Ensembl chr 5:175,318,674...175,403,334
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:25239945) UniProt PMID:25239945 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BFAR bifunctional apoptosis regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:13,558,912...13,597,023
Ensembl chr16:14,980,615...15,018,310
JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789
JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 involved_in ISO (MGI:5571560|PMID:24508390) WB PMID:24508390 MGI:5571560 NCBI chr2A:10,781,671...10,809,235
Ensembl chr2A:10,934,756...10,986,200
JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:94,356,440...94,389,920
Ensembl chr 6:98,242,756...98,274,377
JBrowse link
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:5774886|PMID:27030769) ARUK-UCL PMID:27030769 MGI:5774886 NCBI chr19:62,811...77,897
Ensembl chr19:1,018,095...1,042,104
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,854,918...46,929,509
Ensembl chr20:47,983,098...48,057,421
JBrowse link
PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 involved_in ISO (MGI:3722921|PMID:14729979)
(MGI:3798818|PMID:12667446)
ParkinsonsUK-UCL
UniProt
PMID:12667446 PMID:14729979 MGI:3722921 MGI:3798818 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:3722921|PMID:14729979), (MGI:6467680|PMID:17707796) UniProt PMID:14729979 PMID:17707796 MGI:3722921 MGI:6467680 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,935,691...47,960,055
Ensembl chr14:66,813,953...66,839,866
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G QRICH1 glutamine rich 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:48,954,345...49,018,745
Ensembl chr 3:50,035,676...50,097,596
JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (MGI:5914333|PMID:28797121) MGI PMID:28797121 MGI:5914333 NCBI chr12:121,169,915...121,183,524
Ensembl chr12:125,397,391...125,410,794
JBrowse link
positive regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725
JBrowse link
positive regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator involved_in ISO (PMID:16645094) UniProt PMID:16645094 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:17,446,275...17,489,802
Ensembl chr 7:16,773,281...16,785,879
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:36,260,669...36,281,546
Ensembl chr 4:42,108,335...42,127,575
JBrowse link
positive regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:17,446,275...17,489,802
Ensembl chr 7:16,773,281...16,785,879
JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G TMEM33 transmembrane protein 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:36,260,669...36,281,546
Ensembl chr 4:42,108,335...42,127,575
JBrowse link
positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein NOT|involved_in ISO (PMID:21803450) ARUK-UCL PMID:21803450 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072
JBrowse link
G CREB3 cAMP responsive element binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,583,351...35,587,870
Ensembl chr 9:36,385,867...36,390,540
JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:25239945)
(MGI:5607243|PMID:16332684)
(MGI:5605954|PMID:14559994)
UniProt
ParkinsonsUK-UCL
PMID:14559994 PMID:16332684 PMID:25239945 MGI:5605954 MGI:5607243 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943
JBrowse link
regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIGBOS1 PIGB opposite strand 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:34,286,568...34,325,835
Ensembl chr15:52,610,151...52,610,315
JBrowse link
regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COPS5 COP9 signalosome subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:63,586,062...63,605,213
Ensembl chr 8:65,247,950...65,266,511
JBrowse link
G FICD FIC domain protein adenylyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,086,792...106,092,765
Ensembl chr12:109,482,945...109,488,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15354
    response to stimulus 7931
      response to stress 3676
        response to topologically incorrect protein 106
          response to unfolded protein 89
            cellular response to unfolded protein 75
              endoplasmic reticulum unfolded protein response + 63
              mitochondrial unfolded protein response 1
Path 2
Term Annotations click to browse term
  biological_process 15354
    cellular process 14030
      cellular response to stimulus 6516
        cellular response to chemical stimulus 2805
          cellular response to organic substance 2162
            cellular response to topologically incorrect protein 90
              cellular response to unfolded protein 75
                endoplasmic reticulum unfolded protein response + 63
                mitochondrial unfolded protein response 1
paths to the root