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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to heat
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Accession:GO:0034605 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
Synonyms:exact_synonym: cellular response to heat stress



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cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO1 anoctamin 1 involved_in ISO (MGI:5461590|PMID:22634729) UniProt PMID:22634729 MGI:5461590 NCBI chr18:48,108,310...48,249,021
Ensembl chr18:48,108,806...48,189,471
JBrowse link
G ARPP21 cAMP regulated phosphoprotein 21 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) MGI PMID:18755693 MGI:3821682 NCBI chr23:5,722,575...5,876,923
Ensembl chr23:5,722,727...5,876,487
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO RGD PMID:10748035 RGD:10047286 NCBI chr26:8,148,181...8,209,392
Ensembl chr26:8,148,236...8,209,388
JBrowse link
G ATXN3 ataxin 3 acts_upstream_of_or_within ISO (MGI:4413539|PMID:19843543) MGI PMID:19843543 MGI:4413539 NCBI chr 8:1,318,440...1,354,814
Ensembl chr 8:1,247,155...1,354,720
JBrowse link
G BAG3 BAG cochaperone 3 involved_in ISO (PMID:26159920) UniProt PMID:26159920 NCBI chr28:29,792,612...29,815,466
Ensembl chr28:29,792,777...29,815,138
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO RGD PMID:11295070 RGD:8547793 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281
JBrowse link
G CETN1 centrin 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) MGI PMID:18755693 MGI:3821682 NCBI chr 7:67,431,020...67,431,774
Ensembl chr 7:67,431,081...67,431,599
JBrowse link
G CFTR CF transmembrane conductance regulator ISO RGD PMID:22777528 RGD:11567213 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977
JBrowse link
G CLPB caseinolytic mitochondrial matrix peptidase chaperone subunit B involved_in ISO (PMID:2745427) UniProt PMID:2745427 NCBI chr21:25,710,634...25,855,418
Ensembl chr21:25,710,723...25,852,857
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO RGD PMID:17457469 RGD:2311382 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979
JBrowse link
G DAXX death domain associated protein involved_in ISS UniProt GO_REF:0000024 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340
JBrowse link
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:18854321) UniProt PMID:18854321 NCBI chr23:48,404,351...48,456,360
Ensembl chr23:48,407,316...48,456,654
JBrowse link
G DHX9 DExH-box helicase 9 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) MGI PMID:18755693 MGI:3821682 NCBI chr 7:16,233,763...16,292,576
Ensembl chr 7:16,233,814...16,292,618
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:3500171 PMID:7930798 RGD:10395354 RGD:10395357 NCBI chr 8:41,354,400...41,371,676
Ensembl chr 8:41,351,244...41,371,056
JBrowse link
G FGF1 fibroblast growth factor 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,467,431...37,554,770
Ensembl chr 2:37,470,985...37,554,619
JBrowse link
G HDAC2 histone deacetylase 2 ISO RGD PMID:18849323 RGD:2306446 NCBI chr12:70,053,822...70,083,491
Ensembl chr12:70,053,297...70,103,578
JBrowse link
G HIKESHI heat shock protein nuclear import factor hikeshi involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:13,210,356...13,249,595
Ensembl chr21:13,210,362...13,249,565
JBrowse link
G HMOX1 heme oxygenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G HSF1 heat shock transcription factor 1 involved_in ISO (PMID:8455624), (PMID:9727490)
(PMID:10359787), (PMID:10413683), (PMID:10747973), (PMID:11514557), (PMID:11583998), (PMID:12917326), (PMID:14707147), (PMID:16554823), (PMID:17897941), (PMID:21085490), (PMID:26159920), (PMID:7935471), (PMID:9222587), (PMID:9341107)
RGD
UniProt
PMID:7935471 PMID:8455624 PMID:9222587 PMID:9341107 PMID:9727490 More... RGD:10402942 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
G HSP70 heat shock protein 70 involved_in ISO (PMID:24061851) UniProt PMID:24061851 NCBI chr12:1,285,282...1,287,670 JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in ISO (MGI:6316406|PMID:27496612) UniProt PMID:27496612 MGI:6316406 NCBI chr 8:70,091,203...70,096,107
Ensembl chr 8:70,092,217...70,095,243
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:12,658,415...12,664,945
Ensembl chr12:12,660,008...12,664,940
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:8955942 RGD:10059375 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:24065656 RGD:12910540 NCBI chr37:7,010,421...7,025,912 JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,610,408...48,613,399
Ensembl chr17:48,610,408...48,613,399
JBrowse link
G IER5 immediate early response 5 involved_in ISO (PMID:25816751) UniProt PMID:25816751 NCBI chr 7:14,554,184...14,557,929
Ensembl chr 7:14,555,992...14,556,930
JBrowse link
G IL1A interleukin 1 alpha involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO RGD PMID:23324889 RGD:7495799 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:12372808 RGD:2303719 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
G MKI67 marker of proliferation Ki-67 ISO RGD PMID:9631633 RGD:2317714 NCBI chr28:36,920,679...36,939,336
Ensembl chr28:36,913,023...36,939,486
JBrowse link
G MYOF myoferlin acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) MGI PMID:18755693 MGI:3821682 NCBI chr28:7,602,778...7,745,185
Ensembl chr28:7,603,129...7,745,063
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (MGI:4821029|PMID:20661302) MGI PMID:20661302 MGI:4821029 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:15475520 RGD:5132625 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G PDCD6 programmed cell death 6 involved_in ISO (PMID:21122810) UniProt PMID:21122810 NCBI chr34:11,909,657...11,929,850
Ensembl chr34:11,909,934...11,929,855
JBrowse link
G PDCL3 phosducin like 3 involved_in ISO PMID:27496612 UniProt PMID:27496612 RGD:14695071 NCBI chr10:42,214,127...42,223,986
Ensembl chr10:42,215,120...42,223,906
JBrowse link
G PMP22 peripheral myelin protein 22 acts_upstream_of_or_within ISO (MGI:5517729|PMID:23847051) MGI PMID:23847051 MGI:5517729 NCBI chr 5:38,806,731...38,839,002
Ensembl chr 5:38,807,826...38,838,971
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in ISS UniProt GO_REF:0000024 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:22777528 RGD:11567213 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G RASA3 RAS p21 protein activator 3 acts_upstream_of_or_within ISO PMID:7500386 MGI PMID:7500386 RGD:10047323 NCBI chr22:61,093,762...61,202,209
Ensembl chr22:61,095,044...61,202,152
JBrowse link
G SCARA5 scavenger receptor class A member 5 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3821682|PMID:18755693) Ensembl
MGI
PMID:18755693 GO_REF:0000107 MGI:3821682 NCBI chr25:29,591,248...29,714,159
Ensembl chr25:29,591,294...29,712,173
JBrowse link
G SLC52A3 solute carrier family 52 member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3821682|PMID:18755693) Ensembl
MGI
PMID:18755693 GO_REF:0000107 MGI:3821682 NCBI chr24:20,127,527...20,141,070
Ensembl chr24:20,127,520...20,156,003
JBrowse link
G SLU7 SLU7 homolog, splicing factor involved_in ISO (PMID:21122810) UniProt PMID:21122810 NCBI chr 4:50,314,063...50,328,999
Ensembl chr 4:50,314,086...50,327,733
JBrowse link
G ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3821682|PMID:18755693) Ensembl
MGI
PMID:18755693 GO_REF:0000107 MGI:3821682 NCBI chr27:24,879,103...25,027,014
Ensembl chr27:24,879,380...25,023,618
JBrowse link
G STAC SH3 and cysteine rich domain acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) MGI PMID:18755693 MGI:3821682 NCBI chr23:6,372,337...6,524,334
Ensembl chr23:6,372,257...6,519,748
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in ISO PMID:19953350 ARUK-UCL PMID:19953350 RGD:13507303 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573
JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (PMID:11514557) UniProt PMID:11514557 NCBI chr37:11,199,937...11,229,743
Ensembl chr37:11,200,590...11,229,754
JBrowse link
G TCIM transcriptional and immune response regulator involved_in ISO (PMID:17603013) UniProt PMID:17603013 NCBI chr16:25,212,117...25,213,600
Ensembl chr16:25,213,023...25,213,343
JBrowse link
G TFEC transcription factor EC involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3821682|PMID:18755693) Ensembl
MGI
PMID:18755693 GO_REF:0000107 MGI:3821682 NCBI chr14:54,977,603...55,194,728
Ensembl chr14:54,979,110...55,105,323
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:11295070 RGD:8547793 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in ISO (PMID:17897941) UniProt PMID:17897941 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:22458587 RGD:10043621 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (MGI:5486547|PMID:18174177) UniProt PMID:18174177 MGI:5486547 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165
JBrowse link
G VCP valosin containing protein involved_in ISO (PMID:29804830) UniProt PMID:29804830 NCBI chr11:51,636,986...51,651,749
Ensembl chr11:51,637,411...51,651,714
JBrowse link
G XYLT1 xylosyltransferase 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) MGI PMID:18755693 MGI:3821682 NCBI chr 6:26,742,853...27,041,666
Ensembl chr 6:26,742,853...27,041,666
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:12917326) UniProt PMID:12917326 NCBI chr 9:45,506,830...45,562,081
Ensembl chr 9:45,507,282...45,562,086
JBrowse link
G ZFAND1 zinc finger AN1-type containing 1 NOT|involved_in ISO (PMID:29804830) UniProt PMID:29804830 NCBI chr29:28,799,635...28,825,494
Ensembl chr29:28,808,423...28,825,748
JBrowse link
cellular heat acclimation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSBP1 heat shock factor binding protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:68,474,960...68,479,206
Ensembl chr 5:68,475,948...68,479,145
JBrowse link
G HSP70 heat shock protein 70 involved_in ISO (PMID:21231916) UniProt PMID:21231916 NCBI chr12:1,285,282...1,287,670 JBrowse link
G RBBP7 RB binding protein 7, chromatin remodeling factor involved_in ISO (PMID:7503932) UniProt PMID:7503932 NCBI chr  X:12,981,852...13,006,049
Ensembl chr  X:12,981,860...13,006,045
JBrowse link
mRNA export from nucleus in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLR2D RNA polymerase II subunit D involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:22,754,118...22,774,054
Ensembl chr19:22,754,141...22,774,231
JBrowse link
G TPR translocated promoter region, nuclear basket protein involved_in ISO (PMID:17897941) UniProt PMID:17897941 NCBI chr 7:19,376,951...19,442,368
Ensembl chr 7:19,376,975...19,442,303
JBrowse link
negative regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD34 CD34 molecule involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:6,734,363...6,747,991
Ensembl chr 7:6,734,363...6,748,581
JBrowse link
positive regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IER5 immediate early response 5 involved_in ISO (PMID:26496226) UniProt PMID:26496226 NCBI chr 7:14,554,184...14,557,929
Ensembl chr 7:14,555,992...14,556,930
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHORDC1 cysteine and histidine rich domain containing 1 involved_in ISO (MGI:4837047|PMID:20493909) UniProt PMID:20493909 MGI:4837047 NCBI chr21:10,129,812...10,152,416
Ensembl chr21:10,129,341...10,149,105
JBrowse link
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
G MAPT microtubule associated protein tau involved_in ISO (PMID:21131359)
(MGI:5816445|PMID:21131359)
ParkinsonsUK-UCL PMID:21131359 MGI:5816445 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13874
    response to stimulus 7417
      response to stress 3444
        response to heat 136
          cellular response to heat 63
            cellular heat acclimation 3
            heat shock-mediated polytene chromosome puffing 0
            mRNA export from nucleus in response to heat stress + 2
            negative regulation of cellular response to heat 1
            positive regulation of cellular response to heat 1
            positive regulation of transcription from RNA polymerase II promoter in response to heat stress 1
            regulation of cellular response to heat + 5
            trehalose metabolism in response to heat stress + 0
Path 2
Term Annotations click to browse term
  biological_process 13874
    response to stimulus 7417
      response to abiotic stimulus 1479
        response to temperature stimulus 229
          response to heat 136
            cellular response to heat 63
              cellular heat acclimation 3
              heat shock-mediated polytene chromosome puffing 0
              mRNA export from nucleus in response to heat stress + 2
              negative regulation of cellular response to heat 1
              positive regulation of cellular response to heat 1
              positive regulation of transcription from RNA polymerase II promoter in response to heat stress 1
              regulation of cellular response to heat + 5
              trehalose metabolism in response to heat stress + 0
paths to the root