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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to heat
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Accession:GO:0034605 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
Synonyms:exact_synonym: cellular response to heat stress


show annotations for term's descendants           Sort by:
cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 involved_in ISO (MGI:5461590|PMID:22634729) RGD PMID:22634729 MGI:5461590 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069 		JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IEP RGD PMID:10748035 RGD:10047286 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atxn3 ataxin 3 acts_upstream_of_or_within ISO (MGI:4413539|PMID:19843543) RGD PMID:19843543 MGI:4413539 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bag3 BAG cochaperone 3 involved_in ISO (PMID:26159920) RGD PMID:26159920 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:11295070 RGD:8547793 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cetn1 centrin 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr18:651,591...652,293
Ensembl chr18:651,591...652,293 		JBrowse link
G Cftr CF transmembrane conductance regulator IEP RGD PMID:22777528 RGD:11567213 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Clpb ClpB family mitochondrial disaggregase involved_in ISO
IBA		 (PMID:2745427)
PMID:21873635		 RGD PMID:2745427 PMID:21873635 RGD:13792537 NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP RGD PMID:17457469 RGD:2311382 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Daxx death-domain associated protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:15016915)		 UniProt
RGD		 PMID:15016915 GO_REF:0000024 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:18854321) RGD PMID:18854321 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Dhx9 DExH-box helicase 9 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO (PMID:9499401) RGD PMID:9499401 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA
IEP		 RGD PMID:7930798 PMID:3500171 RGD:10395354, RGD:10395357 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12746488)		 UniProt
RGD		 PMID:12746488 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:18849323 RGD:2306446 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hikeshi heat shock protein nuclear import factor hikeshi involved_in ISO
IEA
ISS		 (PMID:22541429)
GO_REF:0000104
GO_REF:0000024		 RGD
UniProt		 PMID:22541429 GO_REF:0000024 GO_REF:0000104 NCBI chr 1:143,825,922...143,849,374
Ensembl chr 1:143,825,923...143,849,363 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:21597468) RGD PMID:21597468 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in IMP
ISO		 (PMID:10359787), (PMID:10413683), (PMID:10747973), (PMID:11514557), (PMID:11583998), (PMID:12659875), (PMID:12665592), (PMID:12917326), (PMID:14707147), (PMID:16554823), (PMID:17897941), (PMID:21085490), (PMID:26159920), (PMID:7760831), (PMID:7935471), (PMID:8455624), (PMID:9222587), (PMID:9341107), (PMID:9499401), (PMID:9727490) RGD PMID:7760831 PMID:7935471 PMID:8455624 PMID:9222587 PMID:9341107 More... RGD:10402942 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hsf3 heat shock transcription factor 3 acts_upstream_of_or_within ISO (MGI:4441107|PMID:19864465) RGD PMID:19864465 MGI:4441107 NCBI chr  X:61,181,376...61,233,724
Ensembl chr  X:61,182,298...61,295,686 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
IBA		 (MGI:6316406|PMID:27496612)
PMID:21873635		 RGD PMID:27496612 PMID:21873635 MGI:6316406, RGD:13792537 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
IBA		 (MGI:6316406|PMID:27496612)
PMID:21873635		 RGD PMID:27496612 PMID:21873635 MGI:6316406, RGD:13792537 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24061851), (PMID:9499401) RGD PMID:9499401 PMID:24061851 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24061851), (PMID:9499401) RGD PMID:9499401 PMID:24061851 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 involved_in ISO (PMID:21597468), (PMID:24061851) RGD PMID:21597468 PMID:24061851 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:8955942 RGD:10059375 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:24065656 RGD:12910540 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:10971580) RGD PMID:10971580 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Ier5 immediate early response 5 involved_in ISO (PMID:25816751) RGD PMID:25816751 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Il1a interleukin 1 alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:12746488)		 UniProt
Ensembl
RGD		 PMID:12746488 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IDA RGD PMID:23324889 RGD:7495799 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IEP RGD PMID:12372808 RGD:2303719 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mki67 marker of proliferation Ki-67 IEP RGD PMID:9631633 RGD:2317714 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Myof myoferlin acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4821029|PMID:20661302)		 Ensembl
RGD		 PMID:20661302 GO_REF:0000107 MGI:4821029 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nos3 nitric oxide synthase 3 IEP RGD PMID:15475520 RGD:5132625 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO (PMID:21122810) RGD PMID:21122810 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189 		JBrowse link
G Pdcl3 phosducin-like 3 involved_in IDA PMID:27496612 UniProt PMID:27496612 RGD:14695071 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (MGI:5517729|PMID:23847051) RGD PMID:23847051 MGI:5517729 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:21085490)		 UniProt
RGD		 PMID:21085490 GO_REF:0000024 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP RGD PMID:22777528 RGD:11567213 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rasa3 RAS p21 protein activator 3 acts_upstream_of_or_within IDA PMID:7500386 MGI PMID:7500386 RGD:10047323 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804 		JBrowse link
G Scara5 scavenger receptor class A, member 5 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
G Slc52a3 solute carrier family 52 member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3821682|PMID:18755693)		 Ensembl
RGD		 PMID:18755693 GO_REF:0000107 MGI:3821682 NCBI chr 3:140,498,924...140,515,845
Ensembl chr 3:140,509,473...140,514,096 		JBrowse link
G Slu7 SLU7 homolog, splicing factor involved_in ISO
ISS		 (PMID:21122810)
GO_REF:0000024		 RGD
UniProt		 PMID:21122810 GO_REF:0000024 NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349 		JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708 		JBrowse link
G Stac SH3 and cysteine rich domain acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IDA PMID:19953350 ARUK-UCL PMID:19953350 RGD:13507303 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11514557)		 UniProt
RGD		 PMID:11514557 GO_REF:0000024 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Tcim transcriptional and immune response regulator involved_in ISO (PMID:17603013) RGD PMID:17603013 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581 		JBrowse link
G Tfec transcription factor EC acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236 		JBrowse link
G Tp53 tumor protein p53 IEP RGD PMID:11295070 RGD:8547793 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:17897941)		 UniProt
RGD		 PMID:17897941 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP RGD PMID:22458587 RGD:10043621 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IDA		 (PMID:11226139) RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5486547|PMID:18174177)		 UniProt
RGD		 PMID:18174177 GO_REF:0000024 MGI:5486547 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Vcp valosin-containing protein involved_in ISO
ISS		 (PMID:29804830)
GO_REF:0000024		 RGD
UniProt		 PMID:29804830 GO_REF:0000024 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Xylt1 xylosyltransferase 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISS
ISO		 GO_REF:0000024
(PMID:12917326)		 UniProt
RGD		 PMID:12917326 GO_REF:0000024 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
G Zfand1 zinc finger AN1-type containing 1 NOT|involved_in ISO (PMID:29804830) RGD PMID:29804830 NCBI chr 2:91,444,431...91,457,518
Ensembl chr 2:91,444,508...91,453,246 		JBrowse link
cellular heat acclimation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsbp1 heat shock factor binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821 		JBrowse link
G Hsbp1l1 heat shock factor binding protein 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:73,682,286...73,690,061
Ensembl chr18:73,682,286...73,688,045 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 NOT|involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor involved_in ISO
ISS		 (PMID:7503932)
GO_REF:0000024		 RGD
UniProt		 PMID:7503932 GO_REF:0000024 NCBI chr  X:31,913,080...31,931,245
Ensembl chr  X:31,913,081...31,931,226 		JBrowse link
mRNA export from nucleus in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS		 (PMID:17897941)
GO_REF:0000024		 RGD
UniProt		 PMID:17897941 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
positive regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ier5 immediate early response 5 involved_in ISO (PMID:26496226) RGD PMID:26496226 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chordc1 cysteine and histidine rich domain containing 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4837047|PMID:20493909)		 UniProt
RGD		 PMID:20493909 GO_REF:0000024 MGI:4837047 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:11583998) RGD PMID:11583998 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Mapt microtubule-associated protein tau involved_in ISO (PMID:21131359)
(MGI:5816445|PMID:21131359)		 RGD PMID:21131359 MGI:5816445 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      response to stress 4155
        response to heat 101
          cellular response to heat 66
            cellular heat acclimation 6
            heat shock-mediated polytene chromosome puffing 0
            mRNA export from nucleus in response to heat stress + 1
            negative regulation of cellular response to heat 0
            positive regulation of cellular response to heat 1
            positive regulation of transcription from RNA polymerase II promoter in response to heat stress 0
            regulation of cellular response to heat + 4
            trehalose metabolism in response to heat stress + 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      response to abiotic stimulus 1540
        response to temperature stimulus 182
          response to heat 101
            cellular response to heat 66
              cellular heat acclimation 6
              heat shock-mediated polytene chromosome puffing 0
              mRNA export from nucleus in response to heat stress + 1
              negative regulation of cellular response to heat 0
              positive regulation of cellular response to heat 1
              positive regulation of transcription from RNA polymerase II promoter in response to heat stress 0
              regulation of cellular response to heat + 4
              trehalose metabolism in response to heat stress + 0
paths to the root