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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to heat
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Accession:GO:0034605 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
Synonyms:exact_synonym: cellular response to heat stress



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cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 involved_in ISO (MGI:5461590|PMID:22634729) RGD PMID:22634729 MGI:5461590 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 IEP RGD PMID:10748035 RGD:10047286 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atxn3 ataxin 3 acts_upstream_of_or_within ISO (MGI:4413539|PMID:19843543) RGD PMID:19843543 MGI:4413539 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Bag3 BAG cochaperone 3 involved_in ISO (PMID:26159920) RGD PMID:26159920 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:11295070 RGD:8547793 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cetn1 centrin 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr18:651,591...652,293
Ensembl chr18:651,591...652,293
JBrowse link
G Cftr CF transmembrane conductance regulator IEP RGD PMID:22777528 RGD:11567213 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Clpb caseinolytic mitochondrial matrix peptidase chaperone subunit B involved_in ISO
IBA
(PMID:2745427)
PMID:21873635
RGD PMID:2745427 PMID:21873635 RGD:13792537 NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP RGD PMID:17457469 RGD:2311382 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Daxx death-domain associated protein involved_in ISS
ISO
GO_REF:0000024
(PMID:15016915)
UniProt
RGD
PMID:15016915 GO_REF:0000024 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:18854321) RGD PMID:18854321 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dhx9 DExH-box helicase 9 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA
IEP
RGD PMID:7930798 PMID:3500171 RGD:10395354, RGD:10395357 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:12746488)
UniProt
RGD
PMID:12746488 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:18849323 RGD:2306446 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hikeshi heat shock protein nuclear import factor involved_in ISO
ISS
(PMID:22541429)
GO_REF:0000024
RGD
UniProt
PMID:22541429 GO_REF:0000024 NCBI chr 1:143,825,922...143,849,374
Ensembl chr 1:143,825,923...143,849,363
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO (PMID:21597468) RGD PMID:21597468 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in IMP
ISO
(PMID:10359787), (PMID:10413683), (PMID:10747973), (PMID:11514557), (PMID:11583998), (PMID:12917326), (PMID:14707147), (PMID:16554823), (PMID:17897941), (PMID:21085490), (PMID:26159920), (PMID:7935471), (PMID:8455624), (PMID:9222587), (PMID:9341107), (PMID:9727490) RGD PMID:7935471 PMID:8455624 PMID:9222587 PMID:9341107 PMID:9727490 More... RGD:10402942 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
IBA
(MGI:6316406|PMID:27496612)
PMID:21873635
RGD PMID:27496612 PMID:21873635 MGI:6316406, RGD:13792537 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISO
IBA
(MGI:6316406|PMID:27496612)
PMID:21873635
RGD PMID:27496612 PMID:21873635 MGI:6316406, RGD:13792537 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24061851) RGD PMID:24061851
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:24061851) RGD PMID:24061851 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:8955942 RGD:10059375 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP RGD PMID:24065656 RGD:12910540 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:10971580) RGD PMID:10971580 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ier5 immediate early response 5 involved_in ISO (PMID:25816751) RGD PMID:25816751 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Il1a interleukin 1 alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:12746488)
UniProt
Ensembl
RGD
PMID:12746488 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IDA RGD PMID:23324889 RGD:7495799 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) involved_in ISO (PMID:21597468), (PMID:24061851) RGD PMID:21597468 PMID:24061851 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IEP RGD PMID:12372808 RGD:2303719 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Mki67 marker of proliferation Ki-67 IEP RGD PMID:9631633 RGD:2317714 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Myof myoferlin acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4821029|PMID:20661302)
Ensembl
RGD
PMID:20661302 GO_REF:0000107 MGI:4821029 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nos3 nitric oxide synthase 3 IEP RGD PMID:15475520 RGD:5132625 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pdcd6 programmed cell death 6 involved_in ISO (PMID:21122810) RGD PMID:21122810 NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189
JBrowse link
G Pdcl3 phosducin-like 3 involved_in IDA PMID:27496612 UniProt PMID:27496612 RGD:14695071 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (MGI:5517729|PMID:23847051) RGD PMID:23847051 MGI:5517729 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in ISS
ISO
GO_REF:0000024
(PMID:21085490)
UniProt
RGD
PMID:21085490 GO_REF:0000024 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP RGD PMID:22777528 RGD:11567213 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rasa3 RAS p21 protein activator 3 acts_upstream_of_or_within IDA PMID:7500386 MGI PMID:7500386 RGD:10047323 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804
JBrowse link
G Scara5 scavenger receptor class A, member 5 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373
JBrowse link
G Slc52a3 solute carrier family 52 member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3821682|PMID:18755693)
Ensembl
RGD
PMID:18755693 GO_REF:0000107 MGI:3821682 NCBI chr 3:140,498,924...140,515,845
Ensembl chr 3:140,509,473...140,514,096
JBrowse link
G Slu7 SLU7 homolog, splicing factor involved_in ISO
ISS
(PMID:21122810)
GO_REF:0000024
RGD
UniProt
PMID:21122810 GO_REF:0000024 NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 4:175,782,989...175,921,338
Ensembl chr 4:175,789,947...175,920,708
JBrowse link
G Stac SH3 and cysteine rich domain acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IDA PMID:19953350 ARUK-UCL PMID:19953350 RGD:13507303 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:11514557)
UniProt
RGD
PMID:11514557 GO_REF:0000024 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
JBrowse link
G Tcim transcriptional and immune response regulator involved_in ISO (PMID:17603013) RGD PMID:17603013 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
JBrowse link
G Tfec transcription factor EC acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
JBrowse link
G Tp53 tumor protein p53 IEP RGD PMID:11295070 RGD:8547793 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISS
ISO
GO_REF:0000024
(PMID:17897941)
UniProt
RGD
PMID:17897941 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IMP RGD PMID:22458587 RGD:10043621 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IDA
(PMID:11226139) RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISS
ISO
GO_REF:0000024
(MGI:5486547|PMID:18174177)
UniProt
RGD
PMID:18174177 GO_REF:0000024 MGI:5486547 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
JBrowse link
G Vcp valosin-containing protein involved_in ISO
ISS
(PMID:29804830)
GO_REF:0000024
RGD
UniProt
PMID:29804830 GO_REF:0000024 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
G Xylt1 xylosyltransferase 1 acts_upstream_of_or_within ISO (MGI:3821682|PMID:18755693) RGD PMID:18755693 MGI:3821682 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISS
ISO
GO_REF:0000024
(PMID:12917326)
UniProt
RGD
PMID:12917326 GO_REF:0000024 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Zfand1 zinc finger AN1-type containing 1 NOT|involved_in ISO (PMID:29804830) RGD PMID:29804830 NCBI chr 2:91,444,431...91,457,518
Ensembl chr 2:91,444,508...91,453,246
JBrowse link
cellular heat acclimation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsbp1 heat shock factor binding protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821
JBrowse link
G Hsbp1l1 heat shock factor binding protein 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:73,682,286...73,690,061
Ensembl chr18:73,682,286...73,688,045
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:21231916) RGD PMID:21231916
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) NOT|involved_in ISO (PMID:21231916) RGD PMID:21231916 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor involved_in ISO
ISS
(PMID:7503932)
GO_REF:0000024
RGD
UniProt
PMID:7503932 GO_REF:0000024 NCBI chr  X:31,913,080...31,931,245
Ensembl chr  X:31,913,081...31,931,226
JBrowse link
mRNA export from nucleus in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polr2d RNA polymerase II subunit D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:23,418,097...23,425,228
Ensembl chr18:23,418,097...23,425,228
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS
(PMID:17897941)
GO_REF:0000024
RGD
UniProt
PMID:17897941 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
negative regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd34 CD34 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:17505307)
UniProt
RGD
PMID:17505307 GO_REF:0000024 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832
JBrowse link
positive regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ier5 immediate early response 5 involved_in ISO (PMID:26496226) RGD PMID:26496226 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:10747973), (PMID:12659875), (PMID:12665592), (PMID:15016915), (PMID:25963659), (PMID:26754925), (PMID:7760831), (PMID:9499401) RGD PMID:7760831 PMID:9499401 PMID:10747973 PMID:12659875 PMID:12665592 More... NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
regulation of cellular response to heat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chordc1 cysteine and histidine rich domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4837047|PMID:20493909)
UniProt
RGD
PMID:20493909 GO_REF:0000024 MGI:4837047 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:11583998) RGD PMID:11583998 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Mapt microtubule-associated protein tau involved_in ISO (PMID:21131359)
(MGI:5816445|PMID:21131359)
RGD PMID:21131359 MGI:5816445 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    response to stimulus 10209
      response to stress 4153
        response to heat 149
          cellular response to heat 66
            cellular heat acclimation 6
            heat shock-mediated polytene chromosome puffing 0
            mRNA export from nucleus in response to heat stress + 2
            negative regulation of cellular response to heat 1
            positive regulation of cellular response to heat 1
            positive regulation of transcription from RNA polymerase II promoter in response to heat stress 1
            regulation of cellular response to heat + 5
            trehalose metabolism in response to heat stress + 0
Path 2
Term Annotations click to browse term
  biological_process 18737
    response to stimulus 10209
      response to abiotic stimulus 1565
        response to temperature stimulus 245
          response to heat 149
            cellular response to heat 66
              cellular heat acclimation 6
              heat shock-mediated polytene chromosome puffing 0
              mRNA export from nucleus in response to heat stress + 2
              negative regulation of cellular response to heat 1
              positive regulation of cellular response to heat 1
              positive regulation of transcription from RNA polymerase II promoter in response to heat stress 1
              regulation of cellular response to heat + 5
              trehalose metabolism in response to heat stress + 0
paths to the root