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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial unfolded protein response
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Accession:GO:0034514 term browser browse the term
Definition:The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.
Synonyms:exact_synonym: mtUPR



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mitochondrial unfolded protein response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07014739.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Abcb10 ATP binding cassette subfamily B member 10 involved_in ISO (PMID:28315685) RGD PMID:28315685 NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753
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G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    response to stimulus 10363
      response to stress 4035
        response to topologically incorrect protein 142
          response to unfolded protein 120
            cellular response to unfolded protein 99
              mitochondrial unfolded protein response 3
                negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter 0
Path 2
Term Annotations click to browse term
  biological_process 19504
    cellular process 18357
      cellular response to stimulus 8744
        cellular response to chemical stimulus 3545
          cellular response to organic substance 2872
            cellular response to topologically incorrect protein 119
              cellular response to unfolded protein 99
                mitochondrial unfolded protein response 3
                  negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter 0
paths to the root