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ONTOLOGY REPORT - ANNOTATIONS


Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly



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centromere complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpi centromere protein I involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657
JBrowse link
G Cenpo centromere protein O involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314
JBrowse link
G Cenpv centromere protein V involved_in ISO (PMID:18772885) RGD PMID:18772885 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761
JBrowse link
CENP-A containing chromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpp centromere protein P involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:15,013,869...15,189,312
Ensembl chr17:15,014,058...15,189,304
JBrowse link
G Hjurp Holliday junction recognition protein involved_in ISO
IBA
(PMID:19410544), (PMID:19410545)
PMID:21873635
RGD PMID:19410544 PMID:19410545 PMID:21873635 RGD:13792537 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
JBrowse link
G Mis18a MIS18 kinetochore protein A acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:5441069 (MGI:5438906|PMID:22516971)
PMID:21873635
RGD PMID:22516971 PMID:21873635 MGI:5438906, RGD:13792537 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
JBrowse link
G Nasp nuclear autoantigenic sperm protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
JBrowse link
G Oip5 Opa interacting protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250
JBrowse link
kinetochore assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07030926.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002
G Cenpa centromere protein A involved_in ISO (PMID:11682612) RGD PMID:11682612 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpc centromere protein C involved_in ISO
IBA
(PMID:21529714)
PMID:21873635
RGD PMID:21529714 PMID:21873635 RGD:13792537 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:9763420) RGD PMID:9763420 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenph centromere protein H involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,894,253...31,910,182
Ensembl chr 2:31,894,667...31,910,154
JBrowse link
G Cenpk centromere protein K involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:35,360,132...35,421,372
Ensembl chr 2:35,360,132...35,385,706
JBrowse link
G Cenpn centromere protein N involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:44,971,265...44,994,019
Ensembl chr19:44,968,308...44,994,012
JBrowse link
G Cenpt centromere protein T involved_in ISO
ISS
(PMID:21529714)
GO_REF:0000024
RGD
UniProt
PMID:21529714 GO_REF:0000024 NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
JBrowse link
G Cenpw centromere protein W involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:21695110)
UniProt
RGD
PMID:21695110 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
JBrowse link
G Dlgap5 DLG associated protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:16585270)
Ensembl
RGD
PMID:16585270 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:55,739,590...55,747,915
Ensembl chr10:55,739,564...55,751,068
JBrowse link
G Pogz pogo transposable element derived with ZNF domain involved_in ISO (PMID:20562864) RGD PMID:20562864 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707
JBrowse link
pericentric heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpv centromere protein V involved_in ISO
IBA
(PMID:18772885)
PMID:21873635
RGD PMID:18772885 PMID:21873635 RGD:13792537 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589287 (MGI:3528782|PMID:15713842) RGD PMID:15713842 MGI:3528782 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G H3f3a H3.3 histone A acts_upstream_of_or_within ISO MGI:1101768 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr13:92,533,294...92,544,903
Ensembl chr13:92,533,298...92,544,908
JBrowse link
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:1097686 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hells helicase, lymphoid specific involved_in IBA
ISO
PMID:21873635
(MGI:3041983|PMID:14612388)
RGD PMID:14612388 PMID:21873635 MGI:3041983, RGD:13792537 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
regulation of centromere complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:5474462 (MGI:5474379|PMID:23570311) RGD PMID:23570311 MGI:5474379 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
regulation of kinetochore assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf4 ring finger protein 4 involved_in ISO
IEA
ISS
(PMID:20212317)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20212317 GO_REF:0000024 GO_REF:0000107 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
JBrowse link
G Senp6 SUMO specific peptidase 6 involved_in IBA
ISO
PMID:21873635
(PMID:20212317)
RGD PMID:20212317 PMID:21873635 RGD:13792537 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170
JBrowse link
G Trappc12 trafficking protein particle complex subunit 12 involved_in ISO (PMID:25918224) RGD PMID:25918224 NCBI chr 6:45,321,496...45,386,967
Ensembl chr 6:45,321,497...45,386,952
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component organization 6250
          organelle organization 3788
            chromosome organization 900
              centromere complex assembly 28
                CENP-A containing chromatin assembly + 6
                kinetochore assembly + 15
                pericentric heterochromatin assembly + 5
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 19390
    cellular process 18252
      cellular component organization or biogenesis 6492
        cellular component biogenesis 3241
          cellular component assembly 2941
            protein-containing complex assembly 1550
              cellular protein-containing complex assembly 1066
                protein-DNA complex assembly 187
                  centromere complex assembly 28
                    CENP-A containing chromatin assembly + 6
                    kinetochore assembly + 15
                    pericentric heterochromatin assembly + 5
                    regulation of centromere complex assembly + 4
paths to the root