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ONTOLOGY REPORT - ANNOTATIONS

Term:centromere complex assembly
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Accession:GO:0034508 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
Synonyms:exact_synonym: centromere assembly;   centromere organization;   chromosome, centromeric region assembly


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centromere complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpi centromere protein I involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657 		JBrowse link
G Cenpo centromere protein O involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314 		JBrowse link
G Cenpv centromere protein V involved_in ISO (PMID:18772885) RGD PMID:18772885 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761 		JBrowse link
CENP-A containing chromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpa centromere protein A involved_in ISO (PMID:11682612) RGD PMID:11682612 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpi centromere protein I involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657 		JBrowse link
G Cenpn centromere protein N involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:44,971,265...44,994,019
Ensembl chr19:44,968,308...44,994,012 		JBrowse link
G Cenpp centromere protein P involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:15,014,087...15,189,312
Ensembl chr17:15,014,058...15,189,304 		JBrowse link
G Hjurp Holliday junction recognition protein involved_in ISO
IBA		 (PMID:19410544), (PMID:19410545)
PMID:21873635		 RGD PMID:19410544 PMID:19410545 PMID:21873635 RGD:13792537 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728 		JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704 		JBrowse link
G Mis18a MIS18 kinetochore protein A acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:5441069 (MGI:5438906|PMID:22516971)
PMID:21873635		 RGD PMID:22516971 PMID:21873635 MGI:5438906, RGD:13792537 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062 		JBrowse link
G Nasp nuclear autoantigenic sperm protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928 		JBrowse link
G Oip5 Opa interacting protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250 		JBrowse link
kinetochore assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpa centromere protein A involved_in ISO (PMID:11682612) RGD PMID:11682612 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpc centromere protein C involved_in ISO
IBA		 (PMID:21529714)
PMID:21873635		 RGD PMID:21529714 PMID:21873635 RGD:13792537 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476 		JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:9763420) RGD PMID:9763420 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cenph centromere protein H involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154 		JBrowse link
G Cenpk centromere protein K involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706 		JBrowse link
G Cenpt centromere protein T involved_in ISO
IEA
ISS		 (PMID:21529714)
GO_REF:0000002
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:21529714 GO_REF:0000002 GO_REF:0000024 NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142 		JBrowse link
G Cenpw centromere protein W involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:21695110)		 UniProt
RGD		 PMID:21695110 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Cenpwl1 centromere protein W like 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:53,848,491...53,848,803
Ensembl chr  X:53,848,510...53,848,770 		JBrowse link
G Dlgap5 DLG associated protein 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G ENSRNOG00000068966 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr10:13,018,919...13,019,963 JBrowse link
G Mis12 MIS12 kinetochore complex component involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:16585270)		 Ensembl
RGD		 PMID:16585270 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068 		JBrowse link
G Pogz pogo transposable element derived with ZNF domain involved_in ISO (PMID:20562864) RGD PMID:20562864 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707 		JBrowse link
G Sugt1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone acts_upstream_of_or_within
involved_in		 ISO
ISS
IEA		 (MGI:6447440|PMID:32483152)
GO_REF:0000024
(PMID:15133482), (PMID:20404110)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15133482 PMID:20404110 PMID:32483152 GO_REF:0000024 GO_REF:0000107 MGI:6447440 NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150 		JBrowse link
protein localization to kinetochore involved in kinetochore assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kntc1 kinetochore associated 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561 		JBrowse link
regulation of centromere complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:5474462 (MGI:5474379|PMID:23570311) RGD PMID:23570311 MGI:5474379 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
regulation of kinetochore assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf4 ring finger protein 4 involved_in ISO
ISS
IEA		 (PMID:20212317)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:20212317 GO_REF:0000024 GO_REF:0000107 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566 		JBrowse link
G Senp6 SUMO specific peptidase 6 involved_in IBA
ISO		 PMID:21873635
(PMID:20212317)		 RGD PMID:20212317 PMID:21873635 RGD:13792537 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170 		JBrowse link
G Trappc12 trafficking protein particle complex subunit 12 involved_in ISO (PMID:25918224) RGD PMID:25918224 NCBI chr 6:45,321,496...45,386,967
Ensembl chr 6:45,321,497...45,386,952 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular component organization or biogenesis 6802
        cellular component organization 6536
          organelle organization 3601
            chromosome organization 570
              centromere complex assembly 28
                CENP-A containing chromatin assembly 9
                kinetochore assembly + 17
                regulation of centromere complex assembly + 4
Path 2
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular component organization or biogenesis 6802
        cellular component biogenesis 3359
          cellular component assembly 3025
            protein-containing complex assembly 1552
              protein-DNA complex assembly 170
                centromere complex assembly 28
                  CENP-A containing chromatin assembly 9
                  kinetochore assembly + 17
                  regulation of centromere complex assembly + 4
paths to the root